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The map label for this gene is fadH [H]

Identifier: 169628418

GI number: 169628418

Start: 1324574

End: 1326637

Strand: Reverse

Name: fadH [H]

Synonym: MAB_1325c

Alternate gene names: 169628418

Gene position: 1326637-1324574 (Counterclockwise)

Preceding gene: 169628419

Following gene: 169628413

Centisome position: 26.18

GC content: 62.16

Gene sequence:

>2064_bases
ATGTCCCAGCCCGGACTGACGAAAGTGAAATCGATGAGTAATTCGTACCCAACCCTGCTATCCCCCTTGGATCTCGGATT
CACGACGCTGAAGAACCGAGTTGTCATGGGCTCCATGCATGCCGGCCTCGAAGACTTCCCCTGGGACACTCCGGCGCTGG
CGGCCTACTTCGCCGAGCGGGCCAAGGGCGGCGTTGGCATGATCATCACCGGCGGATACGCCATCAATCGCACAGCGTGG
CTCAAACCGCTGGCCGGCAAGCTCACCACCTCCCTGGAGGCGTACCGGCATCGAATAGTCACCAACGCCGTGCACAAGAA
CGGCGGCAAGATCATCGTGCAGCTGCTGCACTCGGGCCGCTACGGCTATCACCCGTTCTCGGTGAGCGCCTCGGCCAAGA
AGTCACCCATCACCCCGTTCAAGCCGCGCAAAATCAGCACCAAGGGTGTCTGGCAGACCATCGACGACTGGGCGCACAGC
GCCAAGATGGCCAAGAAGGCCGGCTACGACGGCTGCGAAATCATGGGCAGCGAAGGCTATTTCATCAATCAATTCCTCGC
GCCTTACACCAATGACCGCACCGACGAATTCGGCGGTAACCCGGAAAACCGGCGACGACTGGCCGTCGAGGTGGTCAAGG
CCGTGCGCAAGGCGGTAGGACCGGACTTCATCATCTGCTACCGACTGTCGATGGCAGATTACGTTCCCGATGGCCAGACC
TGGGATGAAATCGTGGCCCTGGCCAAGGAAATCGAGGCGGCCGGCGCCACCATCATCAACACCGGCATCGGCTGGCACGA
GGCGCGGGTACCCACCATCGTCACCTCGGTGCCGCAGAACGCGTTTGTCGACCTCTCCAACAAGATCGCCCAAGAGGTCC
GTATTCCCGTGATGGCATCCAACCGGATCAACATGCCGCAGTCCGCCGAGCAGATTCTGAACGACGGTCAGGTGCAGCTG
ATTTCGATGGCCAGGCCACTACTGGCCGACCCAGACTGGGTGAACAAGGCATCGGCCGACCACGCCGACGAGATCAACAC
CTGCATCGCGTGCAACCAGGCCTGCCTCGATCACTCCTTCGTGAACAAGAAGGCAAGCTGCCTGCTCAACCCACGGGCCG
GTCATGAGACCACGCTTAAGCTGCTGCCGACCCGGCACACCAAGAAGATCGCTGTGGTGGGCGCCGGTCCGGCAGGACTG
TCGGCCGCCGTCACCGCGGCGCAACGCGGTCACAAGGTGGTGCTGTTCGAGGCCAACGCCGAGATCGGCGGCCAATTCGA
TATGGCCCGCAGAATTCCCGGCAAAGAGGAGTTCAACGAGACCATCCGCTACTACACCACCATGCTCAAGAAGTACGGCG
TCACAGTGCTTTTGAACAAAAAGGTAGACGCCCAGGAACTCATCGCCGGCAAGTTCGACAATGTCATTCTGGCGACCGGC
GTCAAGCCCAGGGTGCCGGCCATCCCCGGTATCGATCACCCGATGGTGCTCTCGTACCCGGAAGTCATCAAGCAAGCCAA
GCCCGTGGGTAAGCGGGTTGCGGTTGTCGGTGCGGGCGGCATCGGCTTCGACGTGTCCGAGTTCCTGACGATTGATGAAT
CGCCCACGCTGAACCTCAAGGAATGGCGCGCCGAGTGGGGCATTTCCGAAGAACACGACGCGCGCGGGTCACTGACGAAA
CCCATTCCCGCCCCGGCAATTCGCGAGGTCTATCTGTGTCAGCGCAAGAAGGGCTCGCTGGGCAAGGGGCTCGGTAAGAC
CACGGGGTGGGTGCACCGTGCTTCCCTCAAGGCCAAGAAGGTCACCGAGCTGGCCGGGGTCAACTACGAGAAGATCGACG
ATGCCGGGCTGCACATCAGTTTCGGCGAGGAGCGTAAGGATCCCCGTGTGCTCGAGGTCGACAATGTGGTGATCTGCGCG
GGCCAGGAGTCGGTGCGCGACCTGGACGACGTGCTCAAAGAGGCCGGGGTCAACGTCCACGTGATCGGCGGGGCGGCGCT
GGCCGCCGAACTCGACGCCAAGCGCGCGATCCGGCAGGGCACCGAGCTCGCCGCCAAGCTATAG

Upstream 100 bases:

>100_bases
GCGGCACTGCACCAATACCTCGTCCTGCGCGGAGGCATCCGCATGGAGGAGGGCTTCACCGATTGGTGCGACGAAATGCT
GTCAGCTTTGTCCAGCTCAC

Downstream 100 bases:

>100_bases
CACTGTCGCGAGCGTGAAGCTGCTGTGGGAAATCAGTGGATTTGTCGCAGCAGCTTCACGCTCGGCGAGCACACCTACAC
CTCGAGGGCGACCTCGTATA

Product: NADPH dependent 2,4-dienoyl-CoA reductase FadH

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MSQPGLTKVKSMSNSYPTLLSPLDLGFTTLKNRVVMGSMHAGLEDFPWDTPALAAYFAERAKGGVGMIITGGYAINRTAW
LKPLAGKLTTSLEAYRHRIVTNAVHKNGGKIIVQLLHSGRYGYHPFSVSASAKKSPITPFKPRKISTKGVWQTIDDWAHS
AKMAKKAGYDGCEIMGSEGYFINQFLAPYTNDRTDEFGGNPENRRRLAVEVVKAVRKAVGPDFIICYRLSMADYVPDGQT
WDEIVALAKEIEAAGATIINTGIGWHEARVPTIVTSVPQNAFVDLSNKIAQEVRIPVMASNRINMPQSAEQILNDGQVQL
ISMARPLLADPDWVNKASADHADEINTCIACNQACLDHSFVNKKASCLLNPRAGHETTLKLLPTRHTKKIAVVGAGPAGL
SAAVTAAQRGHKVVLFEANAEIGGQFDMARRIPGKEEFNETIRYYTTMLKKYGVTVLLNKKVDAQELIAGKFDNVILATG
VKPRVPAIPGIDHPMVLSYPEVIKQAKPVGKRVAVVGAGGIGFDVSEFLTIDESPTLNLKEWRAEWGISEEHDARGSLTK
PIPAPAIREVYLCQRKKGSLGKGLGKTTGWVHRASLKAKKVTELAGVNYEKIDDAGLHISFGEERKDPRVLEVDNVVICA
GQESVRDLDDVLKEAGVNVHVIGGAALAAELDAKRAIRQGTELAAKL

Sequences:

>Translated_687_residues
MSQPGLTKVKSMSNSYPTLLSPLDLGFTTLKNRVVMGSMHAGLEDFPWDTPALAAYFAERAKGGVGMIITGGYAINRTAW
LKPLAGKLTTSLEAYRHRIVTNAVHKNGGKIIVQLLHSGRYGYHPFSVSASAKKSPITPFKPRKISTKGVWQTIDDWAHS
AKMAKKAGYDGCEIMGSEGYFINQFLAPYTNDRTDEFGGNPENRRRLAVEVVKAVRKAVGPDFIICYRLSMADYVPDGQT
WDEIVALAKEIEAAGATIINTGIGWHEARVPTIVTSVPQNAFVDLSNKIAQEVRIPVMASNRINMPQSAEQILNDGQVQL
ISMARPLLADPDWVNKASADHADEINTCIACNQACLDHSFVNKKASCLLNPRAGHETTLKLLPTRHTKKIAVVGAGPAGL
SAAVTAAQRGHKVVLFEANAEIGGQFDMARRIPGKEEFNETIRYYTTMLKKYGVTVLLNKKVDAQELIAGKFDNVILATG
VKPRVPAIPGIDHPMVLSYPEVIKQAKPVGKRVAVVGAGGIGFDVSEFLTIDESPTLNLKEWRAEWGISEEHDARGSLTK
PIPAPAIREVYLCQRKKGSLGKGLGKTTGWVHRASLKAKKVTELAGVNYEKIDDAGLHISFGEERKDPRVLEVDNVVICA
GQESVRDLDDVLKEAGVNVHVIGGAALAAELDAKRAIRQGTELAAKL
>Mature_686_residues
SQPGLTKVKSMSNSYPTLLSPLDLGFTTLKNRVVMGSMHAGLEDFPWDTPALAAYFAERAKGGVGMIITGGYAINRTAWL
KPLAGKLTTSLEAYRHRIVTNAVHKNGGKIIVQLLHSGRYGYHPFSVSASAKKSPITPFKPRKISTKGVWQTIDDWAHSA
KMAKKAGYDGCEIMGSEGYFINQFLAPYTNDRTDEFGGNPENRRRLAVEVVKAVRKAVGPDFIICYRLSMADYVPDGQTW
DEIVALAKEIEAAGATIINTGIGWHEARVPTIVTSVPQNAFVDLSNKIAQEVRIPVMASNRINMPQSAEQILNDGQVQLI
SMARPLLADPDWVNKASADHADEINTCIACNQACLDHSFVNKKASCLLNPRAGHETTLKLLPTRHTKKIAVVGAGPAGLS
AAVTAAQRGHKVVLFEANAEIGGQFDMARRIPGKEEFNETIRYYTTMLKKYGVTVLLNKKVDAQELIAGKFDNVILATGV
KPRVPAIPGIDHPMVLSYPEVIKQAKPVGKRVAVVGAGGIGFDVSEFLTIDESPTLNLKEWRAEWGISEEHDARGSLTKP
IPAPAIREVYLCQRKKGSLGKGLGKTTGWVHRASLKAKKVTELAGVNYEKIDDAGLHISFGEERKDPRVLEVDNVVICAG
QESVRDLDDVLKEAGVNVHVIGGAALAAELDAKRAIRQGTELAAKL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=677, Percent_Identity=53.6189069423929, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=341, Percent_Identity=26.099706744868, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17565138, Length=339, Percent_Identity=24.188790560472, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559802, Length=250, Percent_Identity=28, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=314, Percent_Identity=26.7515923566879, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=311, Percent_Identity=24.1157556270096, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17540738, Length=336, Percent_Identity=24.1071428571429, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=297, Percent_Identity=25.2525252525253, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=274, Percent_Identity=26.2773722627737, Blast_Score=86, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=224, Percent_Identity=30.8035714285714, Blast_Score=88, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=241, Percent_Identity=29.8755186721992, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 74603; Mature: 74471

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPGLTKVKSMSNSYPTLLSPLDLGFTTLKNRVVMGSMHAGLEDFPWDTPALAAYFAER
CCCCCCHHHHHCCCCCCCHHCHHHCCHHHHHCEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AKGGVGMIITGGYAINRTAWLKPLAGKLTTSLEAYRHRIVTNAVHKNGGKIIVQLLHSGR
HCCCEEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCC
YGYHPFSVSASAKKSPITPFKPRKISTKGVWQTIDDWAHSAKMAKKAGYDGCEIMGSEGY
CCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
FINQFLAPYTNDRTDEFGGNPENRRRLAVEVVKAVRKAVGPDFIICYRLSMADYVPDGQT
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCC
WDEIVALAKEIEAAGATIINTGIGWHEARVPTIVTSVPQNAFVDLSNKIAQEVRIPVMAS
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCEEEEC
NRINMPQSAEQILNDGQVQLISMARPLLADPDWVNKASADHADEINTCIACNQACLDHSF
CCCCCCHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VNKKASCLLNPRAGHETTLKLLPTRHTKKIAVVGAGPAGLSAAVTAAQRGHKVVLFEANA
HCCCHHEEECCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCC
EIGGQFDMARRIPGKEEFNETIRYYTTMLKKYGVTVLLNKKVDAQELIAGKFDNVILATG
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCCEEEECC
VKPRVPAIPGIDHPMVLSYPEVIKQAKPVGKRVAVVGAGGIGFDVSEFLTIDESPTLNLK
CCCCCCCCCCCCCCEEECCHHHHHHCCCCCCEEEEEECCCCCCCHHHHEEECCCCCCCHH
EWRAEWGISEEHDARGSLTKPIPAPAIREVYLCQRKKGSLGKGLGKTTGWVHRASLKAKK
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHCCHHH
VTELAGVNYEKIDDAGLHISFGEERKDPRVLEVDNVVICAGQESVRDLDDVLKEAGVNVH
HHHHHCCCHHHCCCCCEEEEECCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHCCCEEE
VIGGAALAAELDAKRAIRQGTELAAKL
EECCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQPGLTKVKSMSNSYPTLLSPLDLGFTTLKNRVVMGSMHAGLEDFPWDTPALAAYFAER
CCCCCHHHHHCCCCCCCHHCHHHCCHHHHHCEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AKGGVGMIITGGYAINRTAWLKPLAGKLTTSLEAYRHRIVTNAVHKNGGKIIVQLLHSGR
HCCCEEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCC
YGYHPFSVSASAKKSPITPFKPRKISTKGVWQTIDDWAHSAKMAKKAGYDGCEIMGSEGY
CCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
FINQFLAPYTNDRTDEFGGNPENRRRLAVEVVKAVRKAVGPDFIICYRLSMADYVPDGQT
CHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCC
WDEIVALAKEIEAAGATIINTGIGWHEARVPTIVTSVPQNAFVDLSNKIAQEVRIPVMAS
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCEEEEC
NRINMPQSAEQILNDGQVQLISMARPLLADPDWVNKASADHADEINTCIACNQACLDHSF
CCCCCCHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VNKKASCLLNPRAGHETTLKLLPTRHTKKIAVVGAGPAGLSAAVTAAQRGHKVVLFEANA
HCCCHHEEECCCCCCCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCC
EIGGQFDMARRIPGKEEFNETIRYYTTMLKKYGVTVLLNKKVDAQELIAGKFDNVILATG
CCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCCEEEECC
VKPRVPAIPGIDHPMVLSYPEVIKQAKPVGKRVAVVGAGGIGFDVSEFLTIDESPTLNLK
CCCCCCCCCCCCCCEEECCHHHHHHCCCCCCEEEEEECCCCCCCHHHHEEECCCCCCCHH
EWRAEWGISEEHDARGSLTKPIPAPAIREVYLCQRKKGSLGKGLGKTTGWVHRASLKAKK
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHCCHHH
VTELAGVNYEKIDDAGLHISFGEERKDPRVLEVDNVVICAGQESVRDLDDVLKEAGVNVH
HHHHHCCCHHHCCCCCEEEEECCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHCCCEEE
VIGGAALAAELDAKRAIRQGTELAAKL
EECCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]