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The map label for this gene is pimE [H]

Identifier: 169628397

GI number: 169628397

Start: 1305612

End: 1306859

Strand: Direct

Name: pimE [H]

Synonym: MAB_1304

Alternate gene names: 169628397

Gene position: 1305612-1306859 (Clockwise)

Preceding gene: 169628395

Following gene: 169628398

Centisome position: 25.77

GC content: 63.78

Gene sequence:

>1248_bases
ATGGCGACCGAGAAAACTGAGCCGACCAGGGCGAATGTCGAGCCCCCAATGCCGACACGCGGCGCGTCGGCGTGGCGCCG
TGTCCGTGCCTGGGGTCCGTGGCTGTTGGGGCTGAGTGTCGCAGTGCGCCTGGCGTGGGCATATCTCACGCCTCATGGCG
CCGATCTGGTCGACCTCCACGTGTACGTCAGCGGTCCGGCGACGTTGGGCCACGGAAATCTTTACGAGTTCACTTACCCG
GACAAAACCCCAGACTTCCCGCTGCCCTTTACTTATCCGCCTTTCGCGGCCGTGGTGTTCTGGCCGCTACACCTGATTCC
CTTCACTCTGCTCGGGCTGTGCTGGATTTTGGGCACCATCGCTGCGCTGTATGCGGTGGTTCGGCTGAGTCAGCGGCTAC
TCGGGTTTGACGACGCGCGTGCGGCGGCGGTGTGGACGGCGGTCACGATGTGGACCGAACCGGTGCGGTCCACCCTGGAC
TACGGACAGATCAACGTGTTGTTGATGCTGCTGATCTTGCTGGCGGTGGCCTCTTCACGCTGGTGGATATCCGGCACATT
GATAGGGCTCGCGGGCGGCGTGAAACTGACCCCACTGGTCAGTGGGCTCTACTTCCTGGGCGCGCGTCGCTGGACGACCG
CCATCTGGGCCGGCGTGGTCTTTCTGCTCACCGTGGTGGTCGGCATCGCCGTGGTAGGGGAGCAGGGGCGGTACTACTTC
ACCGATCTGTTGGGTAAGCCGGACCGGATCGGTCCCATCGCCACCGTGTTCAACCAGTCTTGGCGGGGCGGAATCTCCAG
GATCCTCGGGCATGACGCGGGATCTGGAGTGCTGGTGCTGTTTGCCTACGCGGTCACCGCCATACTCGCTTTCCTGGCAT
GGCGGGCCGTGAACGACAGGCTGGGGCAGATCTGCGTAGTGGAGATGTTCGGTCTGCTCATCTCACCGATCTCCTGGACG
CATCACTGGGTGTGGATGGTTCCGTTCATGGTGTGGCTGCTACACGGTCCGTGGCGAGACAAAGTGGGCGCGAAGGTCTT
TGGATGCGGGTGGCTGGTGCTGCTGTTGATTGGAGTGCCCTGGTTGCTCAGCTTCGCCCAACCTGACATCTGGCGCATCG
ATCGTCCGTGGCCGCTGGCGTGGGCCGGACTGGTGGACATCGTGGCGGCCATAGCAACGCTGACCTGGATGGCGGTGGTG
GGCCGGCGAAGCGGCCACCTTGGTCGGCTACCGTGGCGCCATGTCTGA

Upstream 100 bases:

>100_bases
TAAACGCCAAGGTAATCCGTTACGCGTGTTACTCAAGTGACGCGTGTGGTGTAGACGGAACCGTTACCAAAACGAGTGAG
CGAGGTTATCGAAACTCCCG

Downstream 100 bases:

>100_bases
ACATTGGACCGTCCTGGTCACCGGCGCTTCCAGCGGGATCGGCGCGAGTGCGGCCCGAATCTTCGCAGAACGGGGACACC
GCGTATTCGGAACCAGTCGC

Product: mannosyltransferase

Products: NA

Alternate protein names: Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLHVYVSGPATLGHGNLYEFTYP
DKTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLD
YGQINVLLMLLILLAVASSRWWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYF
TDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDRLGQICVVEMFGLLISPISWT
HHWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVV
GRRSGHLGRLPWRHV

Sequences:

>Translated_415_residues
MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLHVYVSGPATLGHGNLYEFTYP
DKTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLD
YGQINVLLMLLILLAVASSRWWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYF
TDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDRLGQICVVEMFGLLISPISWT
HHWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVV
GRRSGHLGRLPWRHV
>Mature_414_residues
ATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLHVYVSGPATLGHGNLYEFTYPD
KTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTIAALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLDY
GQINVLLMLLILLAVASSRWWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYFT
DLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDRLGQICVVEMFGLLISPISWTH
HWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVPWLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVVG
RRSGHLGRLPWRHV

Specific function: Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol pentamannoside (AcPIM5) to generate a monoacyl phosphatidylinositol hexamannoside (AcPIM6) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PIGM family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 46027; Mature: 45896

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLH
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VYVSGPATLGHGNLYEFTYPDKTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTI
EEEECCCEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLDYGQINVLLMLLILLAVASSR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
WWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYF
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEH
TDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGQICVVEMFGLLISPISWTHHWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCEEHHHHHHHHHHHHHH
WLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVVGRRSGHLGRLPWRHV
HHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATEKTEPTRANVEPPMPTRGASAWRRVRAWGPWLLGLSVAVRLAWAYLTPHGADLVDLH
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VYVSGPATLGHGNLYEFTYPDKTPDFPLPFTYPPFAAVVFWPLHLIPFTLLGLCWILGTI
EEEECCCEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALYAVVRLSQRLLGFDDARAAAVWTAVTMWTEPVRSTLDYGQINVLLMLLILLAVASSR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
WWISGTLIGLAGGVKLTPLVSGLYFLGARRWTTAIWAGVVFLLTVVVGIAVVGEQGRYYF
CEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEH
TDLLGKPDRIGPIATVFNQSWRGGISRILGHDAGSGVLVLFAYAVTAILAFLAWRAVNDR
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGQICVVEMFGLLISPISWTHHWVWMVPFMVWLLHGPWRDKVGAKVFGCGWLVLLLIGVP
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCEEHHHHHHHHHHHHHH
WLLSFAQPDIWRIDRPWPLAWAGLVDIVAAIATLTWMAVVGRRSGHLGRLPWRHV
HHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]