| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is glmU [H]
Identifier: 169628241
GI number: 169628241
Start: 1163187
End: 1164635
Strand: Reverse
Name: glmU [H]
Synonym: MAB_1148c
Alternate gene names: 169628241
Gene position: 1164635-1163187 (Counterclockwise)
Preceding gene: 169628249
Following gene: 169628240
Centisome position: 22.98
GC content: 67.43
Gene sequence:
>1449_bases ATGCCAGGCAATACCGCTGGGACCGCCGTAATCGTGCTGGCCGCGGGCGCCGGCACGCGCATGTGCTCGGATATCCCCAA GGTGCTGCATACCCTCGGGGGCCGCTCCATGCTGGCACACGCCGTATACGCGGCAGCCAGCGTGAATCCCGAGCATCTGG TGATCGTGCTGGGGCACGAACGCGAGCGGATCGCCACCGCCGTCGACATCCTCGCCGAGTCCCTCGGCAGGCGAATCGAG ATCGCGGTCCAGGAACAGCAATTGGGCACCGGACATGCGGTGGCCTGCGGCCTGCAGGCGCTGCCCGCGGGTTTCGCGGG CACCGTCGTCGTCACCTCGGGCGACATCCCGCTGCTCGACGGGGGCACCCTGGCCGGTCTGATCGGCAGCCACACCAGCG AGCCCGCCGCCGCCACTCTGCTGACCACCACACTGACCGATCCCACCGGCTACGGACGCATCCTGCGCACCCAGGACCGC GAGGTTATCGCGATCGTCGAACAGACCGATGCCACTGAGAGTCAGCGCGCCATCGGCGAGGTCAACGCCGGGGTGTACGC CTTCGACATCGAGCCGTTGCACGCGGCCCTCTCGCGGCTGCGCTCAAACAACGCACAGCACGAGCTCTACCTCACCGATG CCGTATCCATCATCCGCGAGAGCGGAAAAGTGGTGCACGCCAATCATGTTGACGACAGCGCACTCGTGGCCGGGGTAAAC GATCGCGTGCAGCTCTCCGAGCTCGGTGCCGAACTGAACCGGCGGATCATCCGCCACCATCAGCGCAACGGCGTCACCAT CATCGACCCATCGAGCACCTGGATCGACGTCGACGTCCACATCGGCCAGGACGCGACCATCGCCCCCGGCACCCAGCTGC ACTCGGCCACCGTGATCGGCGGCCACTGCCACATCGGCCCGGACACCACCCTCATCGATGTCACCGTCGGCGACTCGGCG ACGGTGATCCGCACCCACGGTCAAGGTTCCACCATCGGTGCACGATCGGTCATCGGACCGTTCACCTATCTGCGGCCCGG CACCGTCACCGGCGAAAGCGCCAAGCTCGGCGCCTTCGTCGAGGTGAAGAACTCAACGGTGGGCCGGGGCACCAAGGTGC CGCATCTGACGTACGTGGGCGATGCCGACATCGGCGAACACAGCAACATCGGCGCCTCCAGCGTCTTCGTCAACTACGAC GGAGAGACCAAGCGGCGCACCGTGATTGGCTCGCACGTGAAAACCGGCTCGGACACCATGTTCGTGGCACCGGTCACCGT GGGCGACGGCGCCTACACCGGCGCCGGGACCGTCATCCGCGAGGATGTGCCGCCGGGCGCGCTGGCGGTGTCCGCCGGAC GCCAGCGCAACATCGAAGGCTGGGTGGCGCAGAAGCGTCCGGGCTCGGACGCGGCCAAGGCCGCCGAGGAAGCATCCAAG GGTTCCTGA
Upstream 100 bases:
>100_bases ATTCTGTAACAGTCCGTCGTGGTGTAATCGGCAGCACCTCTGATTTTGGTTCAGATAGTTCAGGTTCGAGTCCTGGCGAC GGAGCAGTAGGGAGTAGGAA
Downstream 100 bases:
>100_bases CCGTCGGGAACCCAGGTTGGACATCTCGCGTTCAAATTCCGGCAACCCCCTCCCGGTCTTCCGGGAAAGGTCCGTACCAT TACCCCGACGGGCGGTACCC
Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase
Products: NA
Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]
Number of amino acids: Translated: 482; Mature: 481
Protein sequence:
>482_residues MPGNTAGTAVIVLAAGAGTRMCSDIPKVLHTLGGRSMLAHAVYAAASVNPEHLVIVLGHERERIATAVDILAESLGRRIE IAVQEQQLGTGHAVACGLQALPAGFAGTVVVTSGDIPLLDGGTLAGLIGSHTSEPAAATLLTTTLTDPTGYGRILRTQDR EVIAIVEQTDATESQRAIGEVNAGVYAFDIEPLHAALSRLRSNNAQHELYLTDAVSIIRESGKVVHANHVDDSALVAGVN DRVQLSELGAELNRRIIRHHQRNGVTIIDPSSTWIDVDVHIGQDATIAPGTQLHSATVIGGHCHIGPDTTLIDVTVGDSA TVIRTHGQGSTIGARSVIGPFTYLRPGTVTGESAKLGAFVEVKNSTVGRGTKVPHLTYVGDADIGEHSNIGASSVFVNYD GETKRRTVIGSHVKTGSDTMFVAPVTVGDGAYTGAGTVIREDVPPGALAVSAGRQRNIEGWVAQKRPGSDAAKAAEEASK GS
Sequences:
>Translated_482_residues MPGNTAGTAVIVLAAGAGTRMCSDIPKVLHTLGGRSMLAHAVYAAASVNPEHLVIVLGHERERIATAVDILAESLGRRIE IAVQEQQLGTGHAVACGLQALPAGFAGTVVVTSGDIPLLDGGTLAGLIGSHTSEPAAATLLTTTLTDPTGYGRILRTQDR EVIAIVEQTDATESQRAIGEVNAGVYAFDIEPLHAALSRLRSNNAQHELYLTDAVSIIRESGKVVHANHVDDSALVAGVN DRVQLSELGAELNRRIIRHHQRNGVTIIDPSSTWIDVDVHIGQDATIAPGTQLHSATVIGGHCHIGPDTTLIDVTVGDSA TVIRTHGQGSTIGARSVIGPFTYLRPGTVTGESAKLGAFVEVKNSTVGRGTKVPHLTYVGDADIGEHSNIGASSVFVNYD GETKRRTVIGSHVKTGSDTMFVAPVTVGDGAYTGAGTVIREDVPPGALAVSAGRQRNIEGWVAQKRPGSDAAKAAEEASK GS >Mature_481_residues PGNTAGTAVIVLAAGAGTRMCSDIPKVLHTLGGRSMLAHAVYAAASVNPEHLVIVLGHERERIATAVDILAESLGRRIEI AVQEQQLGTGHAVACGLQALPAGFAGTVVVTSGDIPLLDGGTLAGLIGSHTSEPAAATLLTTTLTDPTGYGRILRTQDRE VIAIVEQTDATESQRAIGEVNAGVYAFDIEPLHAALSRLRSNNAQHELYLTDAVSIIRESGKVVHANHVDDSALVAGVND RVQLSELGAELNRRIIRHHQRNGVTIIDPSSTWIDVDVHIGQDATIAPGTQLHSATVIGGHCHIGPDTTLIDVTVGDSAT VIRTHGQGSTIGARSVIGPFTYLRPGTVTGESAKLGAFVEVKNSTVGRGTKVPHLTYVGDADIGEHSNIGASSVFVNYDG ETKRRTVIGSHVKTGSDTMFVAPVTVGDGAYTGAGTVIREDVPPGALAVSAGRQRNIEGWVAQKRPGSDAAKAAEEASKG S
Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]
COG id: COG1207
COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]
Homologues:
Organism=Escherichia coli, GI1790168, Length=469, Percent_Identity=38.8059701492537, Blast_Score=281, Evalue=7e-77, Organism=Drosophila melanogaster, GI21355443, Length=412, Percent_Identity=21.1165048543689, Blast_Score=69, Evalue=7e-12, Organism=Drosophila melanogaster, GI24644084, Length=412, Percent_Identity=21.1165048543689, Blast_Score=69, Evalue=7e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005882 - InterPro: IPR005835 - InterPro: IPR011004 [H]
Pfam domain/function: PF00483 NTP_transferase [H]
EC number: =2.7.7.23; =2.3.1.157 [H]
Molecular weight: Translated: 50003; Mature: 49872
Theoretical pI: Translated: 6.34; Mature: 6.34
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 0.6 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPGNTAGTAVIVLAAGAGTRMCSDIPKVLHTLGGRSMLAHAVYAAASVNPEHLVIVLGHE CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCC RERIATAVDILAESLGRRIEIAVQEQQLGTGHAVACGLQALPAGFAGTVVVTSGDIPLLD HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEHHHHHCCCCCCEEEEEECCCEEEEC GGTLAGLIGSHTSEPAAATLLTTTLTDPTGYGRILRTQDREVIAIVEQTDATESQRAIGE CCCEEHHHCCCCCCCCEEEEEEEEECCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHH VNAGVYAFDIEPLHAALSRLRSNNAQHELYLTDAVSIIRESGKVVHANHVDDSALVAGVN CCCCEEEEECCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCEEEECCCCCCEEEECCC DRVQLSELGAELNRRIIRHHQRNGVTIIDPSSTWIDVDVHIGQDATIAPGTQLHSATVIG CCEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCEECCCCCCCEEEEEC GHCHIGPDTTLIDVTVGDSATVIRTHGQGSTIGARSVIGPFTYLRPGTVTGESAKLGAFV CEEEECCCCEEEEEEECCCEEEEEECCCCCCCCCHHHHCCHHEECCCCCCCCCCCCEEEE EVKNSTVGRGTKVPHLTYVGDADIGEHSNIGASSVFVNYDGETKRRTVIGSHVKTGSDTM EECCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCEECCCCEE FVAPVTVGDGAYTGAGTVIREDVPPGALAVSAGRQRNIEGWVAQKRPGSDAAKAAEEASK EEEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHCC GS CC >Mature Secondary Structure PGNTAGTAVIVLAAGAGTRMCSDIPKVLHTLGGRSMLAHAVYAAASVNPEHLVIVLGHE CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCC RERIATAVDILAESLGRRIEIAVQEQQLGTGHAVACGLQALPAGFAGTVVVTSGDIPLLD HHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEHHHHHCCCCCCEEEEEECCCEEEEC GGTLAGLIGSHTSEPAAATLLTTTLTDPTGYGRILRTQDREVIAIVEQTDATESQRAIGE CCCEEHHHCCCCCCCCEEEEEEEEECCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHHH VNAGVYAFDIEPLHAALSRLRSNNAQHELYLTDAVSIIRESGKVVHANHVDDSALVAGVN CCCCEEEEECCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCEEEECCCCCCEEEECCC DRVQLSELGAELNRRIIRHHQRNGVTIIDPSSTWIDVDVHIGQDATIAPGTQLHSATVIG CCEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCEECCCCCCCEEEEEC GHCHIGPDTTLIDVTVGDSATVIRTHGQGSTIGARSVIGPFTYLRPGTVTGESAKLGAFV CEEEECCCCEEEEEEECCCEEEEEECCCCCCCCCHHHHCCHHEECCCCCCCCCCCCEEEE EVKNSTVGRGTKVPHLTYVGDADIGEHSNIGASSVFVNYDGETKRRTVIGSHVKTGSDTM EECCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCEECCCCEE FVAPVTVGDGAYTGAGTVIREDVPPGALAVSAGRQRNIEGWVAQKRPGSDAAKAAEEASK EEEEEEECCCCCCCCCCEEECCCCCCEEEECCCCCCCCCCEEECCCCCCHHHHHHHHHCC GS CC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA