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The map label for this gene is pabB [H]

Identifier: 169628217

GI number: 169628217

Start: 1134764

End: 1136017

Strand: Reverse

Name: pabB [H]

Synonym: MAB_1124c

Alternate gene names: 169628217

Gene position: 1136017-1134764 (Counterclockwise)

Preceding gene: 169628218

Following gene: 169628215

Centisome position: 22.42

GC content: 68.26

Gene sequence:

>1254_bases
ATGCACGTCCAGCAGCTCGGCGATCTCGGCGACCCGCCGGCCGTGCTGCGATCGCTGGCCGCCGCCGCACGCGACACGCA
GCGTCCGGCTCCCGCCGCACTGATCGGTTCTTGGTATGGCTCGCGGGCGATCATCGCACCGTCCTTGGCTACGCGCCCCG
TGCTGCCTCGACAAGCATTCGGCGGCAAGGCCTCTCATGTAGGCACCGTTGCGCCGGGCGCCGTGGGCGGCGGCTGGATC
GGCTATCTGGGATATCCAGACCGGGCGGCAACCGGGCGGGCTCAACGGCTTCCGGCCGCGGCCGGCGGCTGGACCAACGC
GGTACTGCGTCTCGACGAGGACGAATGTTGGTGGTACGAAAGCCTTCTGGATCAAGAATGCCCGGAGTGGATACTGCACG
CATTGACACACCCTTGCGAGCCCGCACCGTGGTCCATCGACTGGACCGCCCCGGACCGTGAGCATCACCGCGGCGCGGTC
GGCCGCTGCCTGGAAGCCATCGCGGCCGGCGAGGTGTACCAAGCCTGCGTATGTACGCAGTTCCGTGGCTCGCTGACCGG
GAAAGCGCTGGACTTTTTCGCCGATGCCGTCACTCGGACAGCACCGGCCCGCGCCGCTTACCTCGCCGGCATCTGGGGCG
CCGTCGCCTCGCTATCTCCCGAATTGTTCTTGCGACGCAACGGCACCGATGTGTGCTCCAGCCCCATCAAGGGCACCCTG
GCGGCGACGGAAGACCCTGCCGCGCTGCTGACGTCGATCAAGGACGTCGCCGAGAACGTGATGATCACCGATCTGGTGCG
CAACGACCTGGGACGCATCGCCGATACCGGCACGGTCACCGTCCCGGAGCTGCTGGCCGTCCATCCGGCGCCCGGCGTGT
GGCATCTGGTGTCCACCGTGGCGGCCAAGGTGCCCGACGAGGCCACCGCCGGCGATCTGCTCGCGGCCGCATTCCCACCC
GCTTCAGTGACAGGCACCCCGAAAACCCGTGCACGCCAACTACTTCGACAATGGGAAGCAGAGCACCGCGGGGTGTACTG
CGGCACCATCGGCATGCTTTCACCCGCGGCCGGCCTGGAACTCAACGTCGCGATCCGCACCGTCGAAATCGCACCGGACG
GCAGCGCCGTGCTGGGCGTGGGCGGCGGCATCACCGCCGACTCCGACGCCGACGCCGAATGGCAGGAATGTCTGCACAAG
GCCGCCGCGACCATCGGCCTCACCGCGATCGCGGAACTCAATCCCGCGCTTTGA

Upstream 100 bases:

>100_bases
ACCCAGCCGGGGTCGAAATCCCAGCAGAATACCCAGCGCCAGGGCTTCTCACTGCTGTACACCCGCGCGATACTGGTGAA
GGGTCTGCGAAACTAGATCG

Downstream 100 bases:

>100_bases
CCACCGCGTCGTAGAGGTCGCGCCGCGACAGCGTGGCGCCGGACTCCCCGATGGCCGTCGCACAGGCCTCACGCAACCCC
ATCCCGTCGTCCATCAATTC

Product: aminodeoxychorismate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MHVQQLGDLGDPPAVLRSLAAAARDTQRPAPAALIGSWYGSRAIIAPSLATRPVLPRQAFGGKASHVGTVAPGAVGGGWI
GYLGYPDRAATGRAQRLPAAAGGWTNAVLRLDEDECWWYESLLDQECPEWILHALTHPCEPAPWSIDWTAPDREHHRGAV
GRCLEAIAAGEVYQACVCTQFRGSLTGKALDFFADAVTRTAPARAAYLAGIWGAVASLSPELFLRRNGTDVCSSPIKGTL
AATEDPAALLTSIKDVAENVMITDLVRNDLGRIADTGTVTVPELLAVHPAPGVWHLVSTVAAKVPDEATAGDLLAAAFPP
ASVTGTPKTRARQLLRQWEAEHRGVYCGTIGMLSPAAGLELNVAIRTVEIAPDGSAVLGVGGGITADSDADAEWQECLHK
AAATIGLTAIAELNPAL

Sequences:

>Translated_417_residues
MHVQQLGDLGDPPAVLRSLAAAARDTQRPAPAALIGSWYGSRAIIAPSLATRPVLPRQAFGGKASHVGTVAPGAVGGGWI
GYLGYPDRAATGRAQRLPAAAGGWTNAVLRLDEDECWWYESLLDQECPEWILHALTHPCEPAPWSIDWTAPDREHHRGAV
GRCLEAIAAGEVYQACVCTQFRGSLTGKALDFFADAVTRTAPARAAYLAGIWGAVASLSPELFLRRNGTDVCSSPIKGTL
AATEDPAALLTSIKDVAENVMITDLVRNDLGRIADTGTVTVPELLAVHPAPGVWHLVSTVAAKVPDEATAGDLLAAAFPP
ASVTGTPKTRARQLLRQWEAEHRGVYCGTIGMLSPAAGLELNVAIRTVEIAPDGSAVLGVGGGITADSDADAEWQECLHK
AAATIGLTAIAELNPAL
>Mature_417_residues
MHVQQLGDLGDPPAVLRSLAAAARDTQRPAPAALIGSWYGSRAIIAPSLATRPVLPRQAFGGKASHVGTVAPGAVGGGWI
GYLGYPDRAATGRAQRLPAAAGGWTNAVLRLDEDECWWYESLLDQECPEWILHALTHPCEPAPWSIDWTAPDREHHRGAV
GRCLEAIAAGEVYQACVCTQFRGSLTGKALDFFADAVTRTAPARAAYLAGIWGAVASLSPELFLRRNGTDVCSSPIKGTL
AATEDPAALLTSIKDVAENVMITDLVRNDLGRIADTGTVTVPELLAVHPAPGVWHLVSTVAAKVPDEATAGDLLAAAFPP
ASVTGTPKTRARQLLRQWEAEHRGVYCGTIGMLSPAAGLELNVAIRTVEIAPDGSAVLGVGGGITADSDADAEWQECLHK
AAATIGLTAIAELNPAL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=279, Percent_Identity=37.9928315412186, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1787518, Length=275, Percent_Identity=28.7272727272727, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=388, Percent_Identity=28.6082474226804, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324361, Length=397, Percent_Identity=27.9596977329975, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 43606; Mature: 43606

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVQQLGDLGDPPAVLRSLAAAARDTQRPAPAALIGSWYGSRAIIAPSLATRPVLPRQAF
CCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCCCCCCCCCHHHC
GGKASHVGTVAPGAVGGGWIGYLGYPDRAATGRAQRLPAAAGGWTNAVLRLDEDECWWYE
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCHHHHHH
SLLDQECPEWILHALTHPCEPAPWSIDWTAPDREHHRGAVGRCLEAIAAGEVYQACVCTQ
HHHHHCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FRGSLTGKALDFFADAVTRTAPARAAYLAGIWGAVASLSPELFLRRNGTDVCSSPIKGTL
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEECCCCHHHCCCCCCCE
AATEDPAALLTSIKDVAENVMITDLVRNDLGRIADTGTVTVPELLAVHPAPGVWHLVSTV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCCHHHHHHHH
AAKVPDEATAGDLLAAAFPPASVTGTPKTRARQLLRQWEAEHRGVYCGTIGMLSPAAGLE
HHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCE
LNVAIRTVEIAPDGSAVLGVGGGITADSDADAEWQECLHKAAATIGLTAIAELNPAL
EEEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHVQQLGDLGDPPAVLRSLAAAARDTQRPAPAALIGSWYGSRAIIAPSLATRPVLPRQAF
CCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECCCCCCCCCCCHHHC
GGKASHVGTVAPGAVGGGWIGYLGYPDRAATGRAQRLPAAAGGWTNAVLRLDEDECWWYE
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCHHHHHH
SLLDQECPEWILHALTHPCEPAPWSIDWTAPDREHHRGAVGRCLEAIAAGEVYQACVCTQ
HHHHHCCHHHHHHHHCCCCCCCCCEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FRGSLTGKALDFFADAVTRTAPARAAYLAGIWGAVASLSPELFLRRNGTDVCSSPIKGTL
HHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEECCCCHHHCCCCCCCE
AATEDPAALLTSIKDVAENVMITDLVRNDLGRIADTGTVTVPELLAVHPAPGVWHLVSTV
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCCCCHHHHHHHH
AAKVPDEATAGDLLAAAFPPASVTGTPKTRARQLLRQWEAEHRGVYCGTIGMLSPAAGLE
HHHCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHCCCCCCCE
LNVAIRTVEIAPDGSAVLGVGGGITADSDADAEWQECLHKAAATIGLTAIAELNPAL
EEEEEEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]