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The map label for this gene is qorA [H]

Identifier: 169628205

GI number: 169628205

Start: 1124607

End: 1125599

Strand: Reverse

Name: qorA [H]

Synonym: MAB_1112c

Alternate gene names: 169628205

Gene position: 1125599-1124607 (Counterclockwise)

Preceding gene: 169628206

Following gene: 169628203

Centisome position: 22.21

GC content: 67.27

Gene sequence:

>993_bases
ATGTATGCGATAACGCTCAACGGTTTTGGCGATCCCGAGGTCATGCAGTGGACGCAGGTAGCCGACCTGCCCGCACCCGG
CCCCGGGGAAGTGACCATCGACGTGGTGGCGGCAGGGGTGAACCGGGCCGACGTGATGCAGCGCCTGGGTCTCTATCCAC
CGCCACCCGGTGTCAGTGAAATACCGGGTCTCGAGGTTTCCGGCCATATCGCCGAAGTTGGCCCCGCAGTACAGGGCTGG
GTGCCCGGTGATGCGGTATGCGCGCTGATGGCGGGCGGCGGATACGCCGAGCGAGTGAACGTGGCCGCCACCCAAGTGCT
GCCCGTGCCGAGGGGCGTCAGCATCACCGCCGCCGCAGCCCTGCCGGAGACCGCCGCCACGGTGTGGTCGAACGTGGTGA
TGACGGGCGGTCTGCGCAGCGGACAGACACTGCTGATTCACGGTGGTGGCAGCGGAATCGGCACGCACGCAATACAAGTG
GGCCGCGCGCTGGGCGCGAATGTGGCGGTGACGGCGGGTACGCAATTCAAGTTGGACCGGTGCCGCGAGCTGGGCGCGCA
CACCCTGATCAATTATCGGGAGCAGGATTTCCCCGCGGTGGTCAACGCGGCATACTCCGGTGCCAACGTCATTCTGGACA
TCGTGGGCGGCGGCTACCTAGCCAAGAATGTGGAGGCGCTGGCCGAAAACGGCCACCTGACGATCATCGGACTGCAGGGC
GGGGCCGCCGCCGAACTGAATCTGGGCGCACTGCTGTTCAAGCGAGGCTCGGTGCACGCGACCAACCTGCGTCGCAGGCC
CGAACAGGGACCAGGCTCCAAGGCCGAGATCATCGCCGAACTGCGGCAGCATTTGTGGCCCTTGATCGCCGAGGGCACCG
TGGCGCCCGTCGTCTCCGCCGAGGTCCCGGTGACCGACGCCGCAGAAGCGCACCGGCTGCTGGACTCGCCGGAGACCGTC
GGCAAGGTCCTGCTCACGGTGCGCCGGCAGTGA

Upstream 100 bases:

>100_bases
GGTCGCCATCGAGATCTCCCCGTCCGAACATTAGCCGGGCTCACCCCCGCCGGCCGAAGCCTTGCGCCACGTTCGGCGAG
CGACCCAAGGAGACAACCCC

Downstream 100 bases:

>100_bases
GCATCGCCACGGCTGAAACGACAAGCAGCCCAACATAGGCCCAGGCGTGCACGGTGTCGGGTAGCCGTGGGGGCCGCCGT
CGCAACCACATCACCAACGG

Product: putative quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MYAITLNGFGDPEVMQWTQVADLPAPGPGEVTIDVVAAGVNRADVMQRLGLYPPPPGVSEIPGLEVSGHIAEVGPAVQGW
VPGDAVCALMAGGGYAERVNVAATQVLPVPRGVSITAAAALPETAATVWSNVVMTGGLRSGQTLLIHGGGSGIGTHAIQV
GRALGANVAVTAGTQFKLDRCRELGAHTLINYREQDFPAVVNAAYSGANVILDIVGGGYLAKNVEALAENGHLTIIGLQG
GAAAELNLGALLFKRGSVHATNLRRRPEQGPGSKAEIIAELRQHLWPLIAEGTVAPVVSAEVPVTDAAEAHRLLDSPETV
GKVLLTVRRQ

Sequences:

>Translated_330_residues
MYAITLNGFGDPEVMQWTQVADLPAPGPGEVTIDVVAAGVNRADVMQRLGLYPPPPGVSEIPGLEVSGHIAEVGPAVQGW
VPGDAVCALMAGGGYAERVNVAATQVLPVPRGVSITAAAALPETAATVWSNVVMTGGLRSGQTLLIHGGGSGIGTHAIQV
GRALGANVAVTAGTQFKLDRCRELGAHTLINYREQDFPAVVNAAYSGANVILDIVGGGYLAKNVEALAENGHLTIIGLQG
GAAAELNLGALLFKRGSVHATNLRRRPEQGPGSKAEIIAELRQHLWPLIAEGTVAPVVSAEVPVTDAAEAHRLLDSPETV
GKVLLTVRRQ
>Mature_330_residues
MYAITLNGFGDPEVMQWTQVADLPAPGPGEVTIDVVAAGVNRADVMQRLGLYPPPPGVSEIPGLEVSGHIAEVGPAVQGW
VPGDAVCALMAGGGYAERVNVAATQVLPVPRGVSITAAAALPETAATVWSNVVMTGGLRSGQTLLIHGGGSGIGTHAIQV
GRALGANVAVTAGTQFKLDRCRELGAHTLINYREQDFPAVVNAAYSGANVILDIVGGGYLAKNVEALAENGHLTIIGLQG
GAAAELNLGALLFKRGSVHATNLRRRPEQGPGSKAEIIAELRQHLWPLIAEGTVAPVVSAEVPVTDAAEAHRLLDSPETV
GKVLLTVRRQ

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=41.0714285714286, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=41.0714285714286, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI194239674, Length=332, Percent_Identity=27.1084337349398, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI13236495, Length=332, Percent_Identity=27.1084337349398, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI24308257, Length=344, Percent_Identity=24.7093023255814, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI18379349, Length=338, Percent_Identity=27.5147928994083, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI194239676, Length=198, Percent_Identity=31.3131313131313, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI47519420, Length=362, Percent_Identity=28.7292817679558, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI28557745, Length=261, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI41872631, Length=317, Percent_Identity=26.4984227129338, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI67078404, Length=333, Percent_Identity=24.9249249249249, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790485, Length=329, Percent_Identity=32.5227963525836, Blast_Score=129, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17507255, Length=312, Percent_Identity=25, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536829, Length=282, Percent_Identity=24.822695035461, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI212642053, Length=309, Percent_Identity=27.831715210356, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=277, Percent_Identity=24.9097472924188, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581345, Length=334, Percent_Identity=26.0479041916168, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920632, Length=342, Percent_Identity=25.7309941520468, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221330659, Length=342, Percent_Identity=25.7309941520468, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34008; Mature: 34008

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAITLNGFGDPEVMQWTQVADLPAPGPGEVTIDVVAAGVNRADVMQRLGLYPPPPGVSE
CEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCC
IPGLEVSGHIAEVGPAVQGWVPGDAVCALMAGGGYAERVNVAATQVLPVPRGVSITAAAA
CCCCCCCCCHHHCCCCCCCCCCHHHHEEEECCCCCHHEEEEEEEEEECCCCCCEEEEHHH
LPETAATVWSNVVMTGGLRSGQTLLIHGGGSGIGTHAIQVGRALGANVAVTAGTQFKLDR
CCHHHHHHHHHHHEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHH
CRELGAHTLINYREQDFPAVVNAAYSGANVILDIVGGGYLAKNVEALAENGHLTIIGLQG
HHHCCHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECC
GAAAELNLGALLFKRGSVHATNLRRRPEQGPGSKAEIIAELRQHLWPLIAEGTVAPVVSA
CCEEEECCCEEEEECCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEC
EVPVTDAAEAHRLLDSPETVGKVLLTVRRQ
CCCCCCHHHHHHHHCCHHHHHHHHHHEECC
>Mature Secondary Structure
MYAITLNGFGDPEVMQWTQVADLPAPGPGEVTIDVVAAGVNRADVMQRLGLYPPPPGVSE
CEEEEECCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCC
IPGLEVSGHIAEVGPAVQGWVPGDAVCALMAGGGYAERVNVAATQVLPVPRGVSITAAAA
CCCCCCCCCHHHCCCCCCCCCCHHHHEEEECCCCCHHEEEEEEEEEECCCCCCEEEEHHH
LPETAATVWSNVVMTGGLRSGQTLLIHGGGSGIGTHAIQVGRALGANVAVTAGTQFKLDR
CCHHHHHHHHHHHEECCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHH
CRELGAHTLINYREQDFPAVVNAAYSGANVILDIVGGGYLAKNVEALAENGHLTIIGLQG
HHHCCHHHHHCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEECC
GAAAELNLGALLFKRGSVHATNLRRRPEQGPGSKAEIIAELRQHLWPLIAEGTVAPVVSA
CCEEEECCCEEEEECCCEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEC
EVPVTDAAEAHRLLDSPETVGKVLLTVRRQ
CCCCCCHHHHHHHHCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]