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The map label for this gene is yngJ [H]

Identifier: 169628168

GI number: 169628168

Start: 1086245

End: 1087402

Strand: Reverse

Name: yngJ [H]

Synonym: MAB_1073c

Alternate gene names: 169628168

Gene position: 1087402-1086245 (Counterclockwise)

Preceding gene: 169628169

Following gene: 169628167

Centisome position: 21.46

GC content: 64.94

Gene sequence:

>1158_bases
GTGACCGCCGTGAATTCTTGGAACACGCCCGAACGCAAGGCACTTCGGGAGACCGTGCGTGATTTCGCCGAGCGCGAGAT
CCTGCCGAATGTCAACGAATGGGAACGTGAGGGGCTGCTCCCGCGCGAATTGCACCGCAAGGCCGGTGATCTGGGCCTGC
TCGGGCCCGGCTCGCCCGAAGCGGTCGGCGGCGGAGGTGGCGATGCCATCGACCCGGTGATCGTGTGCGAGGAACTGCAC
TACGCGGGCGTGCCCGGTGGCGTGTTCGCCTCCCTGTTCACCTGTGGGATCTCCACCCCGCACATGATCGCCTCCGGCGA
TCAGCGGCTCATCGACAATTATGTGAAGCCAACCCTGGCCGGGGAACTGATCGGCTCGCTTGCCATCACCGAACCCGGCG
GCGGGTCCGATGTCGGTCACCTGACCACATCGGCGAAGCGGGACGGCGACCACTACATCGTCAACGGCGCCAAGACCTTC
ATCACCTCCGGTGTACGCGCCGACTATGTGGTGACCGCGGTCCGCACCGGCGGCCCGGGAGCCGCCGGAGTTTCGCTGCT
CCTGATCGACAAGGACACACCGGGATTTGAGGTGGCTCGCAAGCTCGACAAGATGGGCTGGCGTTCCTCGGACACCGCCG
AGCTGTCCTTCACCGACGTGCGTGTACCCGCCGAAAACCTGGTGGGGTCCGAGAACACCGGTTTCGCACAGATCGCGGGC
GCCTTCGTCTCGGAACGCATCGGTCTTGCCGCGCAGGCGTATGCGAGCGCGCAGCGCTGCCTGGACCTGACCGTGGAGTG
GTGCCGCAACCGGGAGACGTTCGGTCGGCCACTCATCTCCCGGCAGTCCGTGCAGAACACACTCGCCGAGATGGCACGCC
GGATCGACGTCGCACGGGTGTACACACACGCGCTGGTCGACCGTGCCATCGCGGGCGAGAGCAACCTGATCGCCGAGGTG
TGCTTCGCCAAGAACACCGCTGTCGAGGCCGGTGAATGGGTGGCCAATCAAGGCGTCCAATTATTCGGGGGCATGGGCTA
TATGGCCGAGAGCGAAATCGAACGGCAGTATCGCGATATGCGCATCATCGGGATCGGTGGTGGCACCACCGAAATCCTCA
CCTCCCTGGCCGCCAAGCTCCTGGGATTCCAGTCATGA

Upstream 100 bases:

>100_bases
GCGTGGCGTATCAAGCCCGGTTCGATCCCCAGGCCAAGGGCATTGGCGAATGGTTGCGTTCCCGCGAGATCGACATCCCT
GAATCCCTGTTAGAAGGAAA

Downstream 100 bases:

>100_bases
CCGTCCTGCGCACCGCCGTCAACACCAACTCGCCCGAGTACATGGCCGCCGCCGAGGCCATGCTGATCAAGCTGGCCGAG
GTCAATGCCGAGACCGCCAA

Product: acyl-CoA dehydrogenase FadE

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTAVNSWNTPERKALRETVRDFAEREILPNVNEWEREGLLPRELHRKAGDLGLLGPGSPEAVGGGGGDAIDPVIVCEELH
YAGVPGGVFASLFTCGISTPHMIASGDQRLIDNYVKPTLAGELIGSLAITEPGGGSDVGHLTTSAKRDGDHYIVNGAKTF
ITSGVRADYVVTAVRTGGPGAAGVSLLLIDKDTPGFEVARKLDKMGWRSSDTAELSFTDVRVPAENLVGSENTGFAQIAG
AFVSERIGLAAQAYASAQRCLDLTVEWCRNRETFGRPLISRQSVQNTLAEMARRIDVARVYTHALVDRAIAGESNLIAEV
CFAKNTAVEAGEWVANQGVQLFGGMGYMAESEIERQYRDMRIIGIGGGTTEILTSLAAKLLGFQS

Sequences:

>Translated_385_residues
MTAVNSWNTPERKALRETVRDFAEREILPNVNEWEREGLLPRELHRKAGDLGLLGPGSPEAVGGGGGDAIDPVIVCEELH
YAGVPGGVFASLFTCGISTPHMIASGDQRLIDNYVKPTLAGELIGSLAITEPGGGSDVGHLTTSAKRDGDHYIVNGAKTF
ITSGVRADYVVTAVRTGGPGAAGVSLLLIDKDTPGFEVARKLDKMGWRSSDTAELSFTDVRVPAENLVGSENTGFAQIAG
AFVSERIGLAAQAYASAQRCLDLTVEWCRNRETFGRPLISRQSVQNTLAEMARRIDVARVYTHALVDRAIAGESNLIAEV
CFAKNTAVEAGEWVANQGVQLFGGMGYMAESEIERQYRDMRIIGIGGGTTEILTSLAAKLLGFQS
>Mature_384_residues
TAVNSWNTPERKALRETVRDFAEREILPNVNEWEREGLLPRELHRKAGDLGLLGPGSPEAVGGGGGDAIDPVIVCEELHY
AGVPGGVFASLFTCGISTPHMIASGDQRLIDNYVKPTLAGELIGSLAITEPGGGSDVGHLTTSAKRDGDHYIVNGAKTFI
TSGVRADYVVTAVRTGGPGAAGVSLLLIDKDTPGFEVARKLDKMGWRSSDTAELSFTDVRVPAENLVGSENTGFAQIAGA
FVSERIGLAAQAYASAQRCLDLTVEWCRNRETFGRPLISRQSVQNTLAEMARRIDVARVYTHALVDRAIAGESNLIAEVC
FAKNTAVEAGEWVANQGVQLFGGMGYMAESEIERQYRDMRIIGIGGGTTEILTSLAAKLLGFQS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=38.3202099737533, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=36.968085106383, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI7656849, Length=372, Percent_Identity=34.1397849462366, Blast_Score=215, Evalue=5e-56,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=32.1899736147757, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=33.0666666666667, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=33.0666666666667, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=32.8488372093023, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI4501859, Length=372, Percent_Identity=30.6451612903226, Blast_Score=182, Evalue=3e-46,
Organism=Homo sapiens, GI21361497, Length=394, Percent_Identity=26.9035532994924, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI76496475, Length=372, Percent_Identity=27.9569892473118, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4557235, Length=372, Percent_Identity=27.9569892473118, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4503943, Length=372, Percent_Identity=25.8064516129032, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI7669494, Length=363, Percent_Identity=25.6198347107438, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI48976061, Length=405, Percent_Identity=24.6913580246914, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI211971008, Length=405, Percent_Identity=24.6913580246914, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI38505218, Length=400, Percent_Identity=24, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI87081958, Length=348, Percent_Identity=30.7471264367816, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1786223, Length=362, Percent_Identity=29.8342541436464, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI87082384, Length=292, Percent_Identity=28.4246575342466, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=377, Percent_Identity=32.8912466843501, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17534899, Length=381, Percent_Identity=33.0708661417323, Blast_Score=208, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17505929, Length=371, Percent_Identity=32.6145552560647, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17551932, Length=369, Percent_Identity=31.9783197831978, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=367, Percent_Identity=30.2452316076294, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17570075, Length=389, Percent_Identity=33.9331619537275, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=377, Percent_Identity=31.8302387267904, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17538396, Length=367, Percent_Identity=30.5177111716621, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17506239, Length=367, Percent_Identity=30.2452316076294, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=253, Percent_Identity=32.0158102766798, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=277, Percent_Identity=31.0469314079422, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71985184, Length=346, Percent_Identity=28.0346820809249, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=31.0344827586207, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=368, Percent_Identity=24.7282608695652, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71985192, Length=286, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=26.0330578512397, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=340, Percent_Identity=24.4117647058824, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356377, Length=365, Percent_Identity=34.7945205479452, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI24660351, Length=368, Percent_Identity=33.1521739130435, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=32.6315789473684, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24646207, Length=365, Percent_Identity=34.7945205479452, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=32.3607427055703, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI281363737, Length=281, Percent_Identity=30.6049822064057, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19920834, Length=297, Percent_Identity=27.6094276094276, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 41083; Mature: 40952

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVNSWNTPERKALRETVRDFAEREILPNVNEWEREGLLPRELHRKAGDLGLLGPGSPE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCC
AVGGGGGDAIDPVIVCEELHYAGVPGGVFASLFTCGISTPHMIASGDQRLIDNYVKPTLA
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHH
GELIGSLAITEPGGGSDVGHLTTSAKRDGDHYIVNGAKTFITSGVRADYVVTAVRTGGPG
HHHHHHEEEECCCCCCCCCHHCCCCCCCCCEEEECCHHHHHHCCCCCCEEEEEEECCCCC
AAGVSLLLIDKDTPGFEVARKLDKMGWRSSDTAELSFTDVRVPAENLVGSENTGFAQIAG
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHCCCCCCCHHHHHH
AFVSERIGLAAQAYASAQRCLDLTVEWCRNRETFGRPLISRQSVQNTLAEMARRIDVARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
YTHALVDRAIAGESNLIAEVCFAKNTAVEAGEWVANQGVQLFGGMGYMAESEIERQYRDM
HHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCE
RIIGIGGGTTEILTSLAAKLLGFQS
EEEEECCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAVNSWNTPERKALRETVRDFAEREILPNVNEWEREGLLPRELHRKAGDLGLLGPGSPE
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHCCCCCCCCCCCCC
AVGGGGGDAIDPVIVCEELHYAGVPGGVFASLFTCGISTPHMIASGDQRLIDNYVKPTLA
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCHHHH
GELIGSLAITEPGGGSDVGHLTTSAKRDGDHYIVNGAKTFITSGVRADYVVTAVRTGGPG
HHHHHHEEEECCCCCCCCCHHCCCCCCCCCEEEECCHHHHHHCCCCCCEEEEEEECCCCC
AAGVSLLLIDKDTPGFEVARKLDKMGWRSSDTAELSFTDVRVPAENLVGSENTGFAQIAG
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHCCCCCCCHHHHHH
AFVSERIGLAAQAYASAQRCLDLTVEWCRNRETFGRPLISRQSVQNTLAEMARRIDVARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
YTHALVDRAIAGESNLIAEVCFAKNTAVEAGEWVANQGVQLFGGMGYMAESEIERQYRDM
HHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCE
RIIGIGGGTTEILTSLAAKLLGFQS
EEEEECCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]