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The map label for this gene is sucC

Identifier: 169628151

GI number: 169628151

Start: 1065715

End: 1066884

Strand: Direct

Name: sucC

Synonym: MAB_1056

Alternate gene names: 169628151

Gene position: 1065715-1066884 (Clockwise)

Preceding gene: 169628149

Following gene: 169628152

Centisome position: 21.03

GC content: 62.74

Gene sequence:

>1170_bases
ATGGATCTTTTCGAGTACCAGGCCAAGGAGCTGTTCGCTAAGCACAATGTGCCGACGACGCCGGGCCGGGTTACCACCAC
CGCCGAGGATGCCAAGGCGATCGCCGAAGAAATCGGCAAGCCGGTGATGATCAAGGCTCAGGTCAAGGTTGGCGGACGTG
GCAAGGCCGGTGGTGTGAAGTACGCCGCCACCCCCGATGACGCTCTTACTCACGCACAGAACATTCTGGGCCTGGACATC
AAGGGCCACATCGTCAAGAAGATCCTCGTCGCCGAGGCCAGCGATATCGCCGAGGAGTACTACATCTCCTTCCTGCTGGA
CCGTGCCAACCGCACCTACCTGGCCATGTGCTCGGTCGAGGGCGGTGTCGAGATCGAGGTAACCGCCGAGGAGAACCCCG
ACGCACTGGCCAAGGTGCCCGTTGACGCCGTCAAGGGTGTCGACCTGGCGCTGGCTCGTGAGATTGCCGAGAAGGGCAAG
TTGCCCGCCGAGGTACTGGACTCCGCCGCGGTGACCATCCAGAAGCTGTGGGAGGTCTTCGTCGGCGAGGATGCCACCCT
GGTGGAGGTCAACCCGCTGGTGCGCACCCCCGACAATCAGATCCTGGCGCTGGACGGCAAGGTCACCCTGGACGGCAACG
CCGATTTCCGTCAGCCCGGCCATGCCGAGTTCGAGGACAAGGACGCCACCGATCCGCTGGAACTCAAGGCCAAGGAGCAC
GACCTCAACTACGTCAAGCTCGATGGTCAGGTCGGCATCATCGGCAACGGCGCAGGTCTGGTCATGTCCACCCTGGATGT
CGTCGCGTATGCGGGCGAGAACCACAACGGCGTGAAGCCTGCCAACTTCCTGGATATCGGTGGTGGCGCCTCGGCCGAGG
TGATGGCTGCCGGTCTTGATGTCATCCTGGGTGACTCGCAGGTCAAGAGCGTTTTTGTGAACGTGTTCGGTGGCATCACC
GCATGTGACGCGGTGGCTAACGGCATCGTCGGCGCCCTGAAGACTCTCGGTAACACGGCCAGCAAGCCGTTGGTGGTTCG
TCTCGACGGCAACAAGGTCGAAGAAGGACGGGCGATTCTGGCCGAGTTCAATCATCCGCTGGTGATCCAGGCCGAGACCA
TGGACGCCGGTGCCGACAAGGCGGCCGCCCTGGCGGCCGCATCCAACTAG

Upstream 100 bases:

>100_bases
CTTACTCAGAAGTAGTGAAGGGCCTTGCTGTGGCCTTGGCTACAGTCCCTAGTGCAATAGTGCCGACCCCGACGTTCGAT
GAGGAAGATGGGCTAGCTAG

Downstream 100 bases:

>100_bases
AGCGCCGAGTCCGCAGATTAAGGGAGCTTGAACCAATGTCTATCTTTCTGAACAAGGATTCGAAGGTCATCGTCCAGGGC
ATCACCGGTGGTGAGGGCAC

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MDLFEYQAKELFAKHNVPTTPGRVTTTAEDAKAIAEEIGKPVMIKAQVKVGGRGKAGGVKYAATPDDALTHAQNILGLDI
KGHIVKKILVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEVTAEENPDALAKVPVDAVKGVDLALAREIAEKGK
LPAEVLDSAAVTIQKLWEVFVGEDATLVEVNPLVRTPDNQILALDGKVTLDGNADFRQPGHAEFEDKDATDPLELKAKEH
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHNGVKPANFLDIGGGASAEVMAAGLDVILGDSQVKSVFVNVFGGIT
ACDAVANGIVGALKTLGNTASKPLVVRLDGNKVEEGRAILAEFNHPLVIQAETMDAGADKAAALAAASN

Sequences:

>Translated_389_residues
MDLFEYQAKELFAKHNVPTTPGRVTTTAEDAKAIAEEIGKPVMIKAQVKVGGRGKAGGVKYAATPDDALTHAQNILGLDI
KGHIVKKILVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEVTAEENPDALAKVPVDAVKGVDLALAREIAEKGK
LPAEVLDSAAVTIQKLWEVFVGEDATLVEVNPLVRTPDNQILALDGKVTLDGNADFRQPGHAEFEDKDATDPLELKAKEH
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHNGVKPANFLDIGGGASAEVMAAGLDVILGDSQVKSVFVNVFGGIT
ACDAVANGIVGALKTLGNTASKPLVVRLDGNKVEEGRAILAEFNHPLVIQAETMDAGADKAAALAAASN
>Mature_389_residues
MDLFEYQAKELFAKHNVPTTPGRVTTTAEDAKAIAEEIGKPVMIKAQVKVGGRGKAGGVKYAATPDDALTHAQNILGLDI
KGHIVKKILVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGVEIEVTAEENPDALAKVPVDAVKGVDLALAREIAEKGK
LPAEVLDSAAVTIQKLWEVFVGEDATLVEVNPLVRTPDNQILALDGKVTLDGNADFRQPGHAEFEDKDATDPLELKAKEH
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHNGVKPANFLDIGGGASAEVMAAGLDVILGDSQVKSVFVNVFGGIT
ACDAVANGIVGALKTLGNTASKPLVVRLDGNKVEEGRAILAEFNHPLVIQAETMDAGADKAAALAAASN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=377, Percent_Identity=36.604774535809, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI157779135, Length=382, Percent_Identity=36.3874345549738, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI294862256, Length=370, Percent_Identity=36.4864864864865, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1786948, Length=392, Percent_Identity=42.3469387755102, Blast_Score=276, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17567829, Length=399, Percent_Identity=36.5914786967419, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=32.75, Blast_Score=221, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6321683, Length=378, Percent_Identity=37.037037037037, Blast_Score=239, Evalue=5e-64,
Organism=Drosophila melanogaster, GI21356231, Length=400, Percent_Identity=34.75, Blast_Score=234, Evalue=8e-62,
Organism=Drosophila melanogaster, GI161078106, Length=401, Percent_Identity=35.1620947630923, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24645208, Length=401, Percent_Identity=35.1620947630923, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI281361397, Length=402, Percent_Identity=35.0746268656716, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI281361395, Length=402, Percent_Identity=35.0746268656716, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_MYCA9 (B1MJJ0)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001701800.1
- ProteinModelPortal:   B1MJJ0
- SMR:   B1MJJ0
- EnsemblBacteria:   EBMYCT00000004889
- GeneID:   5963584
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1056
- GeneTree:   EBGT00050000017263
- HOGENOM:   HBG315432
- OMA:   DAGTEYY
- ProtClustDB:   PRK00696
- BioCyc:   MABS561007:MAB_1056-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 40756; Mature: 40756

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFEYQAKELFAKHNVPTTPGRVTTTAEDAKAIAEEIGKPVMIKAQVKVGGRGKAGGVK
CCHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATPDDALTHAQNILGLDIKGHIVKKILVAEASDIAEEYYISFLLDRANRTYLAMCSVE
EECCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGVEIEVTAEENPDALAKVPVDAVKGVDLALAREIAEKGKLPAEVLDSAAVTIQKLWEVF
CCEEEEEEECCCCCCEEECCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VGEDATLVEVNPLVRTPDNQILALDGKVTLDGNADFRQPGHAEFEDKDATDPLELKAKEH
CCCCCEEEEECCCEECCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHNGVKPANFLDIGGGASAEVMAAGLD
CCCEEEECCEEEEEECCCHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCCHHHHHCCCE
VILGDSQVKSVFVNVFGGITACDAVANGIVGALKTLGNTASKPLVVRLDGNKVEEGRAIL
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEE
AEFNHPLVIQAETMDAGADKAAALAAASN
EECCCCEEEEEECCCCCCCCHHHEEECCC
>Mature Secondary Structure
MDLFEYQAKELFAKHNVPTTPGRVTTTAEDAKAIAEEIGKPVMIKAQVKVGGRGKAGGVK
CCHHHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
YAATPDDALTHAQNILGLDIKGHIVKKILVAEASDIAEEYYISFLLDRANRTYLAMCSVE
EECCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
GGVEIEVTAEENPDALAKVPVDAVKGVDLALAREIAEKGKLPAEVLDSAAVTIQKLWEVF
CCEEEEEEECCCCCCEEECCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VGEDATLVEVNPLVRTPDNQILALDGKVTLDGNADFRQPGHAEFEDKDATDPLELKAKEH
CCCCCEEEEECCCEECCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECC
DLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHNGVKPANFLDIGGGASAEVMAAGLD
CCCEEEECCEEEEEECCCHHHHHHHHHHEECCCCCCCCCCCCEEECCCCCCHHHHHCCCE
VILGDSQVKSVFVNVFGGITACDAVANGIVGALKTLGNTASKPLVVRLDGNKVEEGRAIL
EEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEE
AEFNHPLVIQAETMDAGADKAAALAAASN
EECCCCEEEEEECCCCCCCCHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA