BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is ydfG [C]

Identifier: 169628134

GI number: 169628134

Start: 1048528

End: 1049277

Strand: Direct

Name: ydfG [C]

Synonym: MAB_1039

Alternate gene names: 169628134

Gene position: 1048528-1049277 (Clockwise)

Preceding gene: 169628133

Following gene: 169628135

Centisome position: 20.69

GC content: 66.27

Gene sequence:

>750_bases
GTGACGCGACAGAAGATCCTCATCACCGGGGCGAGCTCCGGCCTGGGTGCCGAGATGGCCCGTCAGTTCGCTGCGAAGGG
ACGGGACCTGGCGCTGTGCGCCCGGCGCACCGAGGCGCTCGAAGAACTCAAGGCAGAGTTGCTGGGCGCCAACCCGGGAA
TCAAGGTCGCGGTGCGGGCGCTGGACGTCACCAACCACGAATCCGTGCCGGTCGTATTCGGCGAGCTGCGCGACGAGCTC
GGCGGCCTGGATCGGGTAGTGGTCAACGCCGGCATCGCCAAGGGTTGGCACCTCGGTGGCGGCAAGTCGTGGGCCAACAT
CCAGACCATCGAAACCAACCTCATCGGTGCACTGGTACAGATCGAGGCGGCGCTAGCCCTGTTCAAGGAACAGGGCTACG
GGCACCTGGTCCTCATCTCCTCGGTGACAGCGGCCAAGGGGCTGCCTGGCACCAAAGCCGCCTATGCGGCCAGCAAGGCC
GGACTTTCCTCGCTGGGTGAATCACTGCGATCCGAATATGCCCGCGGCCCAATCAAAGTCAGCACCATTGAGCCTGGCTA
CATACAGACCGATCTGAGCGCCAAGTCGCCGACCACCCCGATGATGGTCGACACACTGACCGGCGTGACGGCAATGGTGA
ACGCCATCGAGAAGGAGCCCGGCCGCGCGGCGGTGCCGCGATGGCCGTGGGAACCGGTGATGGCGGTCATGCGGTTGCTG
CCGCCCCGGCTGGCGGGGCGCCTCGCGTAA

Upstream 100 bases:

>100_bases
ATTCGCCGATAAGTCGTTCCAGTATTGCCCGACCTGCCAGACCGGTGGCAAGGTGCTAGCCGACCGTCGGCTCTCGCGAC
TGCTCAAATAAAGTGGCAAC

Downstream 100 bases:

>100_bases
TCGGCCGAGGGTTTCCCACATGGGACTTTGTGCCCACGTGGGATGCTGAACCCATGGCCGATCAAGAGAAACCGAACACT
TCAGTCACGGTGGACTACGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEELKAELLGANPGIKVAVRALDVTNHESVPVVFGELRDEL
GGLDRVVVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQGYGHLVLISSVTAAKGLPGTKAAYAASKA
GLSSLGESLRSEYARGPIKVSTIEPGYIQTDLSAKSPTTPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWEPVMAVMRLL
PPRLAGRLA

Sequences:

>Translated_249_residues
MTRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEELKAELLGANPGIKVAVRALDVTNHESVPVVFGELRDEL
GGLDRVVVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQGYGHLVLISSVTAAKGLPGTKAAYAASKA
GLSSLGESLRSEYARGPIKVSTIEPGYIQTDLSAKSPTTPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWEPVMAVMRLL
PPRLAGRLA
>Mature_248_residues
TRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEELKAELLGANPGIKVAVRALDVTNHESVPVVFGELRDELG
GLDRVVVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQIEAALALFKEQGYGHLVLISSVTAAKGLPGTKAAYAASKAG
LSSLGESLRSEYARGPIKVSTIEPGYIQTDLSAKSPTTPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWEPVMAVMRLLP
PRLAGRLA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=35.3535353535354, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI109715829, Length=195, Percent_Identity=31.2820512820513, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=31.1827956989247, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI7657478, Length=202, Percent_Identity=33.6633663366337, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI210032110, Length=243, Percent_Identity=26.3374485596708, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32455239, Length=197, Percent_Identity=30.4568527918782, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031765, Length=197, Percent_Identity=30.4568527918782, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=31, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157739938, Length=188, Percent_Identity=28.7234042553192, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI19743808, Length=206, Percent_Identity=29.6116504854369, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI150247226, Length=200, Percent_Identity=33.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI142976729, Length=204, Percent_Identity=26.9607843137255, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI22507405, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=30.6451612903226, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=34.7368421052632, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI87082100, Length=191, Percent_Identity=32.9842931937173, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786701, Length=264, Percent_Identity=29.9242424242424, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=252, Percent_Identity=26.1904761904762, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=251, Percent_Identity=27.8884462151394, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=251, Percent_Identity=27.8884462151394, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17570069, Length=196, Percent_Identity=31.1224489795918, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559962, Length=217, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=30.8080808080808, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=30.8080808080808, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=207, Percent_Identity=27.536231884058, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=198, Percent_Identity=28.2828282828283, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=223, Percent_Identity=33.6322869955157, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=34.3589743589744, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=31.2820512820513, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=33.6734693877551, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24648693, Length=210, Percent_Identity=30.952380952381, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355889, Length=210, Percent_Identity=30.952380952381, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24641388, Length=212, Percent_Identity=31.6037735849057, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI116007238, Length=196, Percent_Identity=30.1020408163265, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24663911, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI116007234, Length=195, Percent_Identity=30.2564102564103, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648944, Length=198, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281364494, Length=198, Percent_Identity=29.2929292929293, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644339, Length=195, Percent_Identity=31.7948717948718, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24580925, Length=210, Percent_Identity=29.0476190476191, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=31.3131313131313, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26244; Mature: 26113

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEELKAELLGANPGIKVAVRA
CCCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LDVTNHESVPVVFGELRDELGGLDRVVVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQ
EECCCCCCCCHHHHHHHHHHCCHHEEEHHCCCCCCEECCCCCCCCCEEEHHHHHHHHHHH
IEAALALFKEQGYGHLVLISSVTAAKGLPGTKAAYAASKAGLSSLGESLRSEYARGPIKV
HHHHHHHHHHCCCCEEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
STIEPGYIQTDLSAKSPTTPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWEPVMAVMRLL
EEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHC
PPRLAGRLA
CHHHHCCCC
>Mature Secondary Structure 
TRQKILITGASSGLGAEMARQFAAKGRDLALCARRTEALEELKAELLGANPGIKVAVRA
CCCEEEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
LDVTNHESVPVVFGELRDELGGLDRVVVNAGIAKGWHLGGGKSWANIQTIETNLIGALVQ
EECCCCCCCCHHHHHHHHHHCCHHEEEHHCCCCCCEECCCCCCCCCEEEHHHHHHHHHHH
IEAALALFKEQGYGHLVLISSVTAAKGLPGTKAAYAASKAGLSSLGESLRSEYARGPIKV
HHHHHHHHHHCCCCEEEEEECHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
STIEPGYIQTDLSAKSPTTPMMVDTLTGVTAMVNAIEKEPGRAAVPRWPWEPVMAVMRLL
EEECCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHC
PPRLAGRLA
CHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]