Click here to switch to the map view.

The map label for this gene is lrp [C]

Identifier: 169627997

GI number: 169627997

Start: 891513

End: 891986

Strand: Direct

Name: lrp [C]

Synonym: MAB_0898

Alternate gene names: 169627997

Gene position: 891513-891986 (Clockwise)

Preceding gene: 169627992

Following gene: 169628001

Centisome position: 17.59

GC content: 59.7

Gene sequence:

>474_bases
ATGGACAACACAGAAACACTCGTTCAGCTAGACGAGATCGACCGGCGGTTGATCAAGGAGCTGGTCAAGGACGGCCGCGT
GTCGATGCTGGCTTTGGCGCAACGCCTGCATGTTTCGCGTACGCACGTTTATGCTCGCGTCGAGCGACTTGAAAAGGCCG
GGGTGATCGAGGGCTTTGCGGCGCGAATCAACTTGGAACGGGCCGGGTTTGCGACTTCGGCATTAATCGCCCTGACGATC
AGACAGGATTCTTGGCGCAGCCTGTCCGAACAACTGAAGACGCTTCGGTACGTCGAGCGGTTCACCTTCGTGGGCGGGGA
CATTGATGTGCTGGTCGTGGTGCGCGCTCCCGACAACCAGACCCTCCGCGACGTCGTCCTGGAACGGATGCACAGCTTCA
CCGGTATCCGGTCGAGCCGCACCTGGCTGGTGTTCGAAGAATGGAACGCGCTGAGCTCCGAATGGTTGTGCTAG

Upstream 100 bases:

>100_bases
ACAACCTATTTCGAGATACTGAGGATCAATTGACGAACTAGGCTGCGATACGCGTCAAAAAGTTCATATCGAACGTCGAT
CGAAAGCTACCGGTGAACAG

Downstream 100 bases:

>100_bases
CGCTGACGTCGTCGTATGCCTGCGAAACGCCGAAGCGGCGTGCCCCCAAAACCATTGGGCACGCCGCTTCGAACATTCAA
GCTGTCAACCGCGGTTGATC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MDNTETLVQLDEIDRRLIKELVKDGRVSMLALAQRLHVSRTHVYARVERLEKAGVIEGFAARINLERAGFATSALIALTI
RQDSWRSLSEQLKTLRYVERFTFVGGDIDVLVVVRAPDNQTLRDVVLERMHSFTGIRSSRTWLVFEEWNALSSEWLC

Sequences:

>Translated_157_residues
MDNTETLVQLDEIDRRLIKELVKDGRVSMLALAQRLHVSRTHVYARVERLEKAGVIEGFAARINLERAGFATSALIALTI
RQDSWRSLSEQLKTLRYVERFTFVGGDIDVLVVVRAPDNQTLRDVVLERMHSFTGIRSSRTWLVFEEWNALSSEWLC
>Mature_157_residues
MDNTETLVQLDEIDRRLIKELVKDGRVSMLALAQRLHVSRTHVYARVERLEKAGVIEGFAARINLERAGFATSALIALTI
RQDSWRSLSEQLKTLRYVERFTFVGGDIDVLVVVRAPDNQTLRDVVLERMHSFTGIRSSRTWLVFEEWNALSSEWLC

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=141, Percent_Identity=31.9148936170213, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR013249
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 18089; Mature: 18089

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNTETLVQLDEIDRRLIKELVKDGRVSMLALAQRLHVSRTHVYARVERLEKAGVIEGFA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARINLERAGFATSALIALTIRQDSWRSLSEQLKTLRYVERFTFVGGDIDVLVVVRAPDNQ
HHEECHHCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
TLRDVVLERMHSFTGIRSSRTWLVFEEWNALSSEWLC
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MDNTETLVQLDEIDRRLIKELVKDGRVSMLALAQRLHVSRTHVYARVERLEKAGVIEGFA
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ARINLERAGFATSALIALTIRQDSWRSLSEQLKTLRYVERFTFVGGDIDVLVVVRAPDNQ
HHEECHHCCCHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
TLRDVVLERMHSFTGIRSSRTWLVFEEWNALSSEWLC
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]