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The map label for this gene is moaA [H]

Identifier: 169627970

GI number: 169627970

Start: 868453

End: 869445

Strand: Reverse

Name: moaA [H]

Synonym: MAB_0871c

Alternate gene names: 169627970

Gene position: 869445-868453 (Counterclockwise)

Preceding gene: 169627973

Following gene: 169627969

Centisome position: 17.16

GC content: 66.36

Gene sequence:

>993_bases
ATGACCCCGTTAATTGATTCGTTCGGCCGCATCGCGACCGACTTACGGGTGTCGTTGACCGACCGGTGCAATCTGCGCTG
CACCTACTGTATGCCCGCCGAAGGACTGGACTGGCTGCGCAGCGAGACACTGCTCACCACCGATGAATACATCAGACTCA
TCGGGATCGCCGTGACACGCCTCGGGATTGACAGCGTTCGATTCACCGGTGGTGAGCCGCTGATATTCAAGGACCTGGAG
AAGCTCGTTGCCGCCGTCGCCGGCATGTCGCCGCGCCCGGACATTGCCGTCACCACCAACGGCGTCGGACTCGACCGTAA
GGCGGTTGCGCTGCGAGAGGCCGGATTGGACCGCATCAACGTCTCGCTGGATACCTTGGACGCCCATCGTTTTGCCGCGA
TCACCCGGCGGGATCGGCTGTCCGACGTGCTGCTGGGCCTGAAGGCGGCAGGATCTGCCGGGCTGTCGCCGATAAAGATC
AACGCGGTGCTGACACCCGAGCAGTACAAAGAGGATGCCGTCGCCCTGCTGCATTTCAGCCTGGAGCACGGGTACGAACT
GCGGATCATCGAGCAGATGCCCCTGGACGCCGGACACAGCTGGAGCCGGGCCCGCATGGTGACGGCAGACGAGATCCATG
CCGCACTCAGCCGGGAGTTCTCCCTGAGCGAGGATCCCGCGCCCCGCGGCAGCGCCCCAGCGCAACGCTGGCTGGTGAAC
GGGGGCCCGGCGACGGTCGGAATCATCGCGTCGGTGTCCCGGCCGTTCTGTGGCGACTGCGACCGCACCCGGTTGACCGC
GGACGGGCAGGTGCGCAATTGCCTGTTCGCCACCACCGAGACGGATCTGCGCGGCCTGCTCCGCTCGGGCGCGTCCGACG
CCGAGGTGGCATCGGCCTGGCAGGCCGCCATGTGGGGCAAGAAGCCGGGGCACGGCATCAACGACCCGTCCTTCCTGCAG
CCGGACCGCCCGATGAGCGCGATCGGCGGTTAG

Upstream 100 bases:

>100_bases
GTTGGCACTGCACTCACCTCACATGATTAACGCGCCCCAATCAGGACGCGGTGACTGGTCATCCTACTCGGCTCGCGCAA
GTGGTCGCTACGCTGGACTT

Downstream 100 bases:

>100_bases
ATCTGCATGCTTGCGAGCATCACGGTCAGGTATTTCGCGGCCGCCGCGGCGGCTGCCGGGCTTCAGGAAGAAACCGTCGA
TCTGCCCGCCGGGGCGTCAT

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTPLIDSFGRIATDLRVSLTDRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTRLGIDSVRFTGGEPLIFKDLE
KLVAAVAGMSPRPDIAVTTNGVGLDRKAVALREAGLDRINVSLDTLDAHRFAAITRRDRLSDVLLGLKAAGSAGLSPIKI
NAVLTPEQYKEDAVALLHFSLEHGYELRIIEQMPLDAGHSWSRARMVTADEIHAALSREFSLSEDPAPRGSAPAQRWLVN
GGPATVGIIASVSRPFCGDCDRTRLTADGQVRNCLFATTETDLRGLLRSGASDAEVASAWQAAMWGKKPGHGINDPSFLQ
PDRPMSAIGG

Sequences:

>Translated_330_residues
MTPLIDSFGRIATDLRVSLTDRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTRLGIDSVRFTGGEPLIFKDLE
KLVAAVAGMSPRPDIAVTTNGVGLDRKAVALREAGLDRINVSLDTLDAHRFAAITRRDRLSDVLLGLKAAGSAGLSPIKI
NAVLTPEQYKEDAVALLHFSLEHGYELRIIEQMPLDAGHSWSRARMVTADEIHAALSREFSLSEDPAPRGSAPAQRWLVN
GGPATVGIIASVSRPFCGDCDRTRLTADGQVRNCLFATTETDLRGLLRSGASDAEVASAWQAAMWGKKPGHGINDPSFLQ
PDRPMSAIGG
>Mature_329_residues
TPLIDSFGRIATDLRVSLTDRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTRLGIDSVRFTGGEPLIFKDLEK
LVAAVAGMSPRPDIAVTTNGVGLDRKAVALREAGLDRINVSLDTLDAHRFAAITRRDRLSDVLLGLKAAGSAGLSPIKIN
AVLTPEQYKEDAVALLHFSLEHGYELRIIEQMPLDAGHSWSRARMVTADEIHAALSREFSLSEDPAPRGSAPAQRWLVNG
GPATVGIIASVSRPFCGDCDRTRLTADGQVRNCLFATTETDLRGLLRSGASDAEVASAWQAAMWGKKPGHGINDPSFLQP
DRPMSAIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=331, Percent_Identity=40.785498489426, Blast_Score=218, Evalue=6e-57,
Organism=Homo sapiens, GI22027536, Length=331, Percent_Identity=40.785498489426, Blast_Score=217, Evalue=1e-56,
Organism=Escherichia coli, GI1786999, Length=333, Percent_Identity=34.5345345345345, Blast_Score=178, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI32566329, Length=334, Percent_Identity=35.0299401197605, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI17561210, Length=336, Percent_Identity=35.7142857142857, Blast_Score=204, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI32566331, Length=317, Percent_Identity=34.384858044164, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI28574488, Length=333, Percent_Identity=39.039039039039, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI28574490, Length=328, Percent_Identity=38.109756097561, Blast_Score=204, Evalue=9e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 35662; Mature: 35531

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLIDSFGRIATDLRVSLTDRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTR
CCCCHHHHHHHHHHEEEEEECCCCCEEEEECCCCCHHHHHHCCEECHHHHHHHHHHHHHH
LGIDSVRFTGGEPLIFKDLEKLVAAVAGMSPRPDIAVTTNGVGLDRKAVALREAGLDRIN
HCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEE
VSLDTLDAHRFAAITRRDRLSDVLLGLKAAGSAGLSPIKINAVLTPEQYKEDAVALLHFS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHEEEEEH
LEHGYELRIIEQMPLDAGHSWSRARMVTADEIHAALSREFSLSEDPAPRGSAPAQRWLVN
HCCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEC
GGPATVGIIASVSRPFCGDCDRTRLTADGQVRNCLFATTETDLRGLLRSGASDAEVASAW
CCCCEEEEEEECCCCCCCCCCCCEECCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHH
QAAMWGKKPGHGINDPSFLQPDRPMSAIGG
HHHHCCCCCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
TPLIDSFGRIATDLRVSLTDRCNLRCTYCMPAEGLDWLRSETLLTTDEYIRLIGIAVTR
CCCHHHHHHHHHHEEEEEECCCCCEEEEECCCCCHHHHHHCCEECHHHHHHHHHHHHHH
LGIDSVRFTGGEPLIFKDLEKLVAAVAGMSPRPDIAVTTNGVGLDRKAVALREAGLDRIN
HCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEE
VSLDTLDAHRFAAITRRDRLSDVLLGLKAAGSAGLSPIKINAVLTPEQYKEDAVALLHFS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHHEEEEEH
LEHGYELRIIEQMPLDAGHSWSRARMVTADEIHAALSREFSLSEDPAPRGSAPAQRWLVN
HCCCCEEEEEEECCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCHHHEEEC
GGPATVGIIASVSRPFCGDCDRTRLTADGQVRNCLFATTETDLRGLLRSGASDAEVASAW
CCCCEEEEEEECCCCCCCCCCCCEECCCCCCCEEEEECCHHHHHHHHHCCCCHHHHHHHH
QAAMWGKKPGHGINDPSFLQPDRPMSAIGG
HHHHCCCCCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA