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The map label for this gene is ampC [C]

Identifier: 169627952

GI number: 169627952

Start: 849544

End: 850743

Strand: Direct

Name: ampC [C]

Synonym: MAB_0853

Alternate gene names: 169627952

Gene position: 849544-850743 (Clockwise)

Preceding gene: 169627951

Following gene: 169627953

Centisome position: 16.77

GC content: 64.0

Gene sequence:

>1200_bases
ATGAGCACAAGCCTTGATGTCGCGGTGAACGGCACCAACTCACCGGATTTCGATAACGTCCGGCGCGCATTCGCGCTGAA
CTTCCTGGAGAACGACGAATTGGGTGCGGCCGTAGCGATCTGGGTTGACGGGGAACTCGTCGTCAACCTGTGGGCCGGCT
GGGCCGACGAGGCGCGCACCCGCCCGTGGACGGAAGACACCTTGGCGCCGGTGTATTCGGGAACCAAGGGCCTGATGAGC
ACCTGCGTTCACATGCTCGTCGAGCGCGGTGTGCTCGATCTGTATGCTCCCGTCGCGCGCTACTGGCCTGAATTCGGCCA
GGGCGGTAAGGAATCCATCACGCTGGCGATGGTGCTCGGGCACCGCTCGGGTGTGATCGGCCCGCGTACCCGGTTGACTC
CGGAGCAGGCGGCCAACTGGGACGAGGTGTGCGAGCACATCGCGCGGGCGACTCCGTGGTGGGAGCCCGGAACCGCCCAG
GGTTACCACATGGCCACGTTCGGATTCATTCTCGGCGAGGTCGTTCGCCGCACCACGGGTAAGACGCTCGGGCAGTTCCT
GCGTACCGAGATCGCCGAGCCCTATGGGCTGGATGTGCACGTGGGACTGCCGCACAGCGAGCATCACCGGTGCGCAGAAC
TGATCAACAAGCCGTACCTGCGCGATGTGTTTCGCGGTGCGCCCGGCGAATTCGACTGCATGAGTGATCACCCGCTGGCA
GGTCCGCTCATCTCGGGCGACTTCATCCCCGACGACGAGATCGCCCGCAAGGACATCGCGCTGTGGCGCGCGTTGGAGTT
CCCCGGCACCAACGCGCACGTTTCCGCGCTGGGCATGGCCACCTTCTACAACGCCATGGCCCTCGGCAAGCTGCTCAGTC
ACGAGCACATGGATGTGGTGCGGGTGTCCCAAGGTGGATTCGATCCTGATGTGGTGCTGGGTCCCCGGGTGGCGAACCAC
GGATGGGGTCTGGGCTACATGCTCAACCAGCGCTGCTACGCAGGGCCCAACCAGAAGACGTTCGGGCATGGCGGGTCCGG
TGGGTCCTATGCCTTCGTCGATCTGGAGCACCGCATCGGCTACTCGTATGTGATGAACCAATTCGACGTGACCAAGGCGG
ATGCTGATCCCCGGAGTGTGCGGCTGATCAACGAGCTCTACACCACATTGGGGGTGTCACCGGCGGGAGAATCGCTGTGA

Upstream 100 bases:

>100_bases
TAGCACGCGTGGTTTACCAGCGTGTCGCGCAGTCACAGTTCGTTTCCTGAATCCGCGGCACAGGCGCCGCATTGAGCAGC
ATTGGAAGGTTGGCATTGCC

Downstream 100 bases:

>100_bases
CGGCAACGATTCAGGAGACCAAGGCGCACGCGGTCGCGACATCCGGCTCGATCGCTCATCTGGACTTCGTCGATCAGGCA
TCTTTCCTCGGTTTGCGTGC

Product: esterase/lipase LipP

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: Esterase; Carboxylesterase; Beta-Lactamase Class C; Esterase A; Esterase/Lipase LipP; Lactone Hydrolase; Lipase LipE; Esterase/Lipase/Beta-Lactamase; Beta-Lactamase Protein; Esterase LipL; Lipase LipD; Lipase/Esterase/Beta-Lactamase; Beta-Lactamase Family Protein; Hydrolase; Beta-Lactamase Class C Family Protein; Esterase/Lipase; Carboxylesterase EstC; Serine Hydrolase; Beta-Lactamase Family; Fusion Of Enoyl-CoA Hydratase; Beta-Lactamase-Like Protein

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSTSLDVAVNGTNSPDFDNVRRAFALNFLENDELGAAVAIWVDGELVVNLWAGWADEARTRPWTEDTLAPVYSGTKGLMS
TCVHMLVERGVLDLYAPVARYWPEFGQGGKESITLAMVLGHRSGVIGPRTRLTPEQAANWDEVCEHIARATPWWEPGTAQ
GYHMATFGFILGEVVRRTTGKTLGQFLRTEIAEPYGLDVHVGLPHSEHHRCAELINKPYLRDVFRGAPGEFDCMSDHPLA
GPLISGDFIPDDEIARKDIALWRALEFPGTNAHVSALGMATFYNAMALGKLLSHEHMDVVRVSQGGFDPDVVLGPRVANH
GWGLGYMLNQRCYAGPNQKTFGHGGSGGSYAFVDLEHRIGYSYVMNQFDVTKADADPRSVRLINELYTTLGVSPAGESL

Sequences:

>Translated_399_residues
MSTSLDVAVNGTNSPDFDNVRRAFALNFLENDELGAAVAIWVDGELVVNLWAGWADEARTRPWTEDTLAPVYSGTKGLMS
TCVHMLVERGVLDLYAPVARYWPEFGQGGKESITLAMVLGHRSGVIGPRTRLTPEQAANWDEVCEHIARATPWWEPGTAQ
GYHMATFGFILGEVVRRTTGKTLGQFLRTEIAEPYGLDVHVGLPHSEHHRCAELINKPYLRDVFRGAPGEFDCMSDHPLA
GPLISGDFIPDDEIARKDIALWRALEFPGTNAHVSALGMATFYNAMALGKLLSHEHMDVVRVSQGGFDPDVVLGPRVANH
GWGLGYMLNQRCYAGPNQKTFGHGGSGGSYAFVDLEHRIGYSYVMNQFDVTKADADPRSVRLINELYTTLGVSPAGESL
>Mature_398_residues
STSLDVAVNGTNSPDFDNVRRAFALNFLENDELGAAVAIWVDGELVVNLWAGWADEARTRPWTEDTLAPVYSGTKGLMST
CVHMLVERGVLDLYAPVARYWPEFGQGGKESITLAMVLGHRSGVIGPRTRLTPEQAANWDEVCEHIARATPWWEPGTAQG
YHMATFGFILGEVVRRTTGKTLGQFLRTEIAEPYGLDVHVGLPHSEHHRCAELINKPYLRDVFRGAPGEFDCMSDHPLAG
PLISGDFIPDDEIARKDIALWRALEFPGTNAHVSALGMATFYNAMALGKLLSHEHMDVVRVSQGGFDPDVVLGPRVANHG
WGLGYMLNQRCYAGPNQKTFGHGGSGGSYAFVDLEHRIGYSYVMNQFDVTKADADPRSVRLINELYTTLGVSPAGESL

Specific function: This Protein Is A Serine Beta-Lactamase With A Substrate Specificity For Cephalosporins. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17538001, Length=409, Percent_Identity=32.0293398533007, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71983659, Length=414, Percent_Identity=29.4685990338164, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17535191, Length=371, Percent_Identity=33.4231805929919, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17538474, Length=409, Percent_Identity=29.3398533007335, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17535177, Length=400, Percent_Identity=28, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71983666, Length=313, Percent_Identity=31.629392971246, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI71990590, Length=395, Percent_Identity=25.3164556962025, Blast_Score=115, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 43774; Mature: 43643

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSLDVAVNGTNSPDFDNVRRAFALNFLENDELGAAVAIWVDGELVVNLWAGWADEART
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCHHHHCC
RPWTEDTLAPVYSGTKGLMSTCVHMLVERGVLDLYAPVARYWPEFGQGGKESITLAMVLG
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHCCCCCCCEEEEEEEC
HRSGVIGPRTRLTPEQAANWDEVCEHIARATPWWEPGTAQGYHMATFGFILGEVVRRTTG
CCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KTLGQFLRTEIAEPYGLDVHVGLPHSEHHRCAELINKPYLRDVFRGAPGEFDCMSDHPLA
HHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCC
GPLISGDFIPDDEIARKDIALWRALEFPGTNAHVSALGMATFYNAMALGKLLSHEHMDVV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
RVSQGGFDPDVVLGPRVANHGWGLGYMLNQRCYAGPNQKTFGHGGSGGSYAFVDLEHRIG
EECCCCCCCCEEECCEECCCCCCHHHHHCCHHCCCCCCCCCCCCCCCCCEEEEEEHHHCC
YSYVMNQFDVTKADADPRSVRLINELYTTLGVSPAGESL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STSLDVAVNGTNSPDFDNVRRAFALNFLENDELGAAVAIWVDGELVVNLWAGWADEART
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCHHHHCC
RPWTEDTLAPVYSGTKGLMSTCVHMLVERGVLDLYAPVARYWPEFGQGGKESITLAMVLG
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCHHHCCCCCCCEEEEEEEC
HRSGVIGPRTRLTPEQAANWDEVCEHIARATPWWEPGTAQGYHMATFGFILGEVVRRTTG
CCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KTLGQFLRTEIAEPYGLDVHVGLPHSEHHRCAELINKPYLRDVFRGAPGEFDCMSDHPLA
HHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCC
GPLISGDFIPDDEIARKDIALWRALEFPGTNAHVSALGMATFYNAMALGKLLSHEHMDVV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
RVSQGGFDPDVVLGPRVANHGWGLGYMLNQRCYAGPNQKTFGHGGSGGSYAFVDLEHRIG
EECCCCCCCCEEECCEECCCCCCHHHHHCCHHCCCCCCCCCCCCCCCCCEEEEEEHHHCC
YSYVMNQFDVTKADADPRSVRLINELYTTLGVSPAGESL
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA