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The map label for this gene is mmlH [H]

Identifier: 169627872

GI number: 169627872

Start: 768994

End: 770919

Strand: Reverse

Name: mmlH [H]

Synonym: MAB_0771c

Alternate gene names: 169627872

Gene position: 770919-768994 (Counterclockwise)

Preceding gene: 169627873

Following gene: 169627870

Centisome position: 15.21

GC content: 64.95

Gene sequence:

>1926_bases
ATGAGCAATATCAAGATCACCGTCGACGGCAAGGTCCTCATGGACACCGACCCAGGTAAGTGGCGTTCCACGCCGCCGGA
TATCCCCGACCTTAAGCGCCAATCCGGCGGGCAGGATTGGGGTCTGGCCGTGATAGTCACTCTCGCACAGGCGGGCACGC
TGGCCGAGCTGGGCCAGCCCACTGGGAACACCACGATGACCATCACTACCCGCGCCAACGGCTGGACGCTGGATGTGGAG
CAGGACGGCAGCGAGCCATCCGTCGCACCCGGGAAGGGTCGTGCCTGCGCCCACTGCACCGCCAGCGCACGCCGAGGCCG
ATACAAGCGCTGGGCGCCAAGGATTTTCGTCGGATGTGGTGATCATGGAACCCTATGTCGCCGAGGCCCGACCATAAGGC
CAGCACCACCGATCGCGGTCTGGGCTGGAAACTACGGACTCTTATGCCGCCTTCCGCTCAGGCTCGACTGGGGCCTGAGC
GGCTGGCAGCTGGCGAATCTGCGGATCTTTTGCGCAATCCTGCGGACTTTTAATCCGCAGGTCCCAGGTTCGAGCCCTGG
TGGGGCACCAGATCATCCGTTGCAATCAGCGGGAGCAGGAGCCTTACCAGGCCGTCGACCGGCTCATACCGTTCGGCCAA
TGACTTCCACGGCCGAGAACACCACCGGGACGCACCCGCCCCAATCCCGTCCCGTGACGTTCCGGCAGGCGTTCTTCGTC
GCGTTGACCGCAGGCCTCGGGTACGGGTTCGACTCCTACGCGGTGAACATCTACGGCCTAGTGCTACCGGAGATCAAGGA
CACACTGCACATCACCGAGGCGCAGGCCGGGTACATCGGCTCGATCTTCCTGCTCGGGTACACCATCGGCACCGTCGGAT
TCGGCCTCGCCGCCGATCGCTGGGGCCGGAAGACCACCCTCGGGGCCTCGATCCTGCTGTATGGCATAACCACCGCCCTG
GCCGGCCTGACCACCAATGTGGCCGCGTTCACCGGGTTGCGCTTTTTGACGGGTGTGGGCGGTGCCGGCGAGCTCGCGGT
CGGCGCGCCCTACACCGCCGAGGTGTGGCCGGCCAAGACACGGGCCATCGGCGTTGGTGGCGTGATCTTTTCGCTCTTCT
CACTCGGTTACGTCCTGGCCGCCGGGGTCGCACTCGTATTGGTCCCGCGGTTTGGCTGGCAGGCGGCATTCATCGTCGCG
ATCATCCCCGCGGTGGTGCTTTTCCTTGCCCGCCAAGGCATCAAGGAATCGCACCGCTACACCCAAACCAAGGCGCGCGT
CCAAGGCCGTGCCACCAGGCCGAAGCTGTGGCATGTTCCCGGAGTACGGCGGCGCCTCGTCGTCGGCTGGCTCGTCTACA
CCGCCAATGCGGTCGGCTACTGGGGCATGACCCTGTTCTTGACCACCTACATCGTCAAGAAGTTTCATGCCACCTCCATT
GACGCGATCCGTTACGCCCTCGCCTTCTTCCTGCTACAGGCTGTGTTCGTCTTCATCGGCACCGCACTGGCCGACCGGAT
CGGGCGGCGACCCTCGGCCGTCCTCGGCGCCCTGATCGAAATCGCCTCCACCGCATTGGGAGCCACTTCGGACACCCTGC
CGGAGTACCTGGTGTTCGGCGCCATCTCCATCGCCACCTTGGGCTGGCTGTGGGGAGTCGGTGACACCTACGTCGCCGAA
CTCTTCCCCACCGTGCTACGCGGCACCGGGTTCGGCATCGCCGTCGGCGGCGGCCGCGTCGTCTCCATCGCGGCGCCGGC
CCTGGTGGGCTGGGCCATCACGCATTACGGAATCCAAACGCCCTACCTGGCTCTCAGCGGCCTGTGGATACTGACGATCA
TCGGATACCTGCTTGGACCGGAAACCAAGGGTAAAGAGCTGGAAGACCTTGCCGACGAGGCGCTTACCGAGGATCTGCCG
GGCTGA

Upstream 100 bases:

>100_bases
GCACCGACCACCAGCGCGCCACGCCCTTGTTGGTGCTGACGGTCGGCAAGACCGACGACGTGACGATCGATGCCCGTCAA
CTACGAAAGTTCCTAGCCCA

Downstream 100 bases:

>100_bases
TCGCTAAGCGACCTCGCACACCTGTCCGCCGGTGATCCGGACAAGCTCGGCGAAGGTGAGCGGAAAGACAGTGCGCGGCG
TGCCACCGGCCGCCCAGATC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MSNIKITVDGKVLMDTDPGKWRSTPPDIPDLKRQSGGQDWGLAVIVTLAQAGTLAELGQPTGNTTMTITTRANGWTLDVE
QDGSEPSVAPGKGRACAHCTASARRGRYKRWAPRIFVGCGDHGTLCRRGPTIRPAPPIAVWAGNYGLLCRLPLRLDWGLS
GWQLANLRIFCAILRTFNPQVPGSSPGGAPDHPLQSAGAGALPGRRPAHTVRPMTSTAENTTGTHPPQSRPVTFRQAFFV
ALTAGLGYGFDSYAVNIYGLVLPEIKDTLHITEAQAGYIGSIFLLGYTIGTVGFGLAADRWGRKTTLGASILLYGITTAL
AGLTTNVAAFTGLRFLTGVGGAGELAVGAPYTAEVWPAKTRAIGVGGVIFSLFSLGYVLAAGVALVLVPRFGWQAAFIVA
IIPAVVLFLARQGIKESHRYTQTKARVQGRATRPKLWHVPGVRRRLVVGWLVYTANAVGYWGMTLFLTTYIVKKFHATSI
DAIRYALAFFLLQAVFVFIGTALADRIGRRPSAVLGALIEIASTALGATSDTLPEYLVFGAISIATLGWLWGVGDTYVAE
LFPTVLRGTGFGIAVGGGRVVSIAAPALVGWAITHYGIQTPYLALSGLWILTIIGYLLGPETKGKELEDLADEALTEDLP
G

Sequences:

>Translated_641_residues
MSNIKITVDGKVLMDTDPGKWRSTPPDIPDLKRQSGGQDWGLAVIVTLAQAGTLAELGQPTGNTTMTITTRANGWTLDVE
QDGSEPSVAPGKGRACAHCTASARRGRYKRWAPRIFVGCGDHGTLCRRGPTIRPAPPIAVWAGNYGLLCRLPLRLDWGLS
GWQLANLRIFCAILRTFNPQVPGSSPGGAPDHPLQSAGAGALPGRRPAHTVRPMTSTAENTTGTHPPQSRPVTFRQAFFV
ALTAGLGYGFDSYAVNIYGLVLPEIKDTLHITEAQAGYIGSIFLLGYTIGTVGFGLAADRWGRKTTLGASILLYGITTAL
AGLTTNVAAFTGLRFLTGVGGAGELAVGAPYTAEVWPAKTRAIGVGGVIFSLFSLGYVLAAGVALVLVPRFGWQAAFIVA
IIPAVVLFLARQGIKESHRYTQTKARVQGRATRPKLWHVPGVRRRLVVGWLVYTANAVGYWGMTLFLTTYIVKKFHATSI
DAIRYALAFFLLQAVFVFIGTALADRIGRRPSAVLGALIEIASTALGATSDTLPEYLVFGAISIATLGWLWGVGDTYVAE
LFPTVLRGTGFGIAVGGGRVVSIAAPALVGWAITHYGIQTPYLALSGLWILTIIGYLLGPETKGKELEDLADEALTEDLP
G
>Mature_640_residues
SNIKITVDGKVLMDTDPGKWRSTPPDIPDLKRQSGGQDWGLAVIVTLAQAGTLAELGQPTGNTTMTITTRANGWTLDVEQ
DGSEPSVAPGKGRACAHCTASARRGRYKRWAPRIFVGCGDHGTLCRRGPTIRPAPPIAVWAGNYGLLCRLPLRLDWGLSG
WQLANLRIFCAILRTFNPQVPGSSPGGAPDHPLQSAGAGALPGRRPAHTVRPMTSTAENTTGTHPPQSRPVTFRQAFFVA
LTAGLGYGFDSYAVNIYGLVLPEIKDTLHITEAQAGYIGSIFLLGYTIGTVGFGLAADRWGRKTTLGASILLYGITTALA
GLTTNVAAFTGLRFLTGVGGAGELAVGAPYTAEVWPAKTRAIGVGGVIFSLFSLGYVLAAGVALVLVPRFGWQAAFIVAI
IPAVVLFLARQGIKESHRYTQTKARVQGRATRPKLWHVPGVRRRLVVGWLVYTANAVGYWGMTLFLTTYIVKKFHATSID
AIRYALAFFLLQAVFVFIGTALADRIGRRPSAVLGALIEIASTALGATSDTLPEYLVFGAISIATLGWLWGVGDTYVAEL
FPTVLRGTGFGIAVGGGRVVSIAAPALVGWAITHYGIQTPYLALSGLWILTIIGYLLGPETKGKELEDLADEALTEDLPG

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=409, Percent_Identity=24.6943765281174, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI87082404, Length=410, Percent_Identity=26.3414634146341, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87082231, Length=206, Percent_Identity=30.0970873786408, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788068, Length=425, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790550, Length=405, Percent_Identity=21.9753086419753, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87082159, Length=410, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 68079; Mature: 67947

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIKITVDGKVLMDTDPGKWRSTPPDIPDLKRQSGGQDWGLAVIVTLAQAGTLAELGQP
CCCEEEEECCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHCCC
TGNTTMTITTRANGWTLDVEQDGSEPSVAPGKGRACAHCTASARRGRYKRWAPRIFVGCG
CCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEEEEC
DHGTLCRRGPTIRPAPPIAVWAGNYGLLCRLPLRLDWGLSGWQLANLRIFCAILRTFNPQ
CCCCHHCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCC
VPGSSPGGAPDHPLQSAGAGALPGRRPAHTVRPMTSTAENTTGTHPPQSRPVTFRQAFFV
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALTAGLGYGFDSYAVNIYGLVLPEIKDTLHITEAQAGYIGSIFLLGYTIGTVGFGLAADR
HHHHHCCCCCCHHEEEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHH
WGRKTTLGASILLYGITTALAGLTTNVAAFTGLRFLTGVGGAGELAVGAPYTAEVWPAKT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCH
RAIGVGGVIFSLFSLGYVLAAGVALVLVPRFGWQAAFIVAIIPAVVLFLARQGIKESHRY
HEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQTKARVQGRATRPKLWHVPGVRRRLVVGWLVYTANAVGYWGMTLFLTTYIVKKFHATSI
HHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHH
DAIRYALAFFLLQAVFVFIGTALADRIGRRPSAVLGALIEIASTALGATSDTLPEYLVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AISIATLGWLWGVGDTYVAELFPTVLRGTGFGIAVGGGRVVSIAAPALVGWAITHYGIQT
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCC
PYLALSGLWILTIIGYLLGPETKGKELEDLADEALTEDLPG
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNIKITVDGKVLMDTDPGKWRSTPPDIPDLKRQSGGQDWGLAVIVTLAQAGTLAELGQP
CCEEEEECCEEEEECCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHCCC
TGNTTMTITTRANGWTLDVEQDGSEPSVAPGKGRACAHCTASARRGRYKRWAPRIFVGCG
CCCEEEEEEEECCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEEEEC
DHGTLCRRGPTIRPAPPIAVWAGNYGLLCRLPLRLDWGLSGWQLANLRIFCAILRTFNPQ
CCCCHHCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHCCCC
VPGSSPGGAPDHPLQSAGAGALPGRRPAHTVRPMTSTAENTTGTHPPQSRPVTFRQAFFV
CCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
ALTAGLGYGFDSYAVNIYGLVLPEIKDTLHITEAQAGYIGSIFLLGYTIGTVGFGLAADR
HHHHHCCCCCCHHEEEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHH
WGRKTTLGASILLYGITTALAGLTTNVAAFTGLRFLTGVGGAGELAVGAPYTAEVWPAKT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCH
RAIGVGGVIFSLFSLGYVLAAGVALVLVPRFGWQAAFIVAIIPAVVLFLARQGIKESHRY
HEEEHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQTKARVQGRATRPKLWHVPGVRRRLVVGWLVYTANAVGYWGMTLFLTTYIVKKFHATSI
HHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCHH
DAIRYALAFFLLQAVFVFIGTALADRIGRRPSAVLGALIEIASTALGATSDTLPEYLVFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AISIATLGWLWGVGDTYVAELFPTVLRGTGFGIAVGGGRVVSIAAPALVGWAITHYGIQT
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCCEEEEEHHHHHHHHHHHHHCCCC
PYLALSGLWILTIIGYLLGPETKGKELEDLADEALTEDLPG
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]