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The map label for this gene is mshD

Identifier: 169627846

GI number: 169627846

Start: 745117

End: 746007

Strand: Direct

Name: mshD

Synonym: MAB_0745

Alternate gene names: 169627846

Gene position: 745117-746007 (Clockwise)

Preceding gene: 169627845

Following gene: 169627847

Centisome position: 14.7

GC content: 66.11

Gene sequence:

>891_bases
ATGACCGAATGGGTCCCGCTTCTCGATAATCGGCGCCAACTACAGATCCGCGAGTTGATTGTCGAGGCCACCCGCGCCGA
CGGCATCGCCCCGGTGGGTGAACAGGTATTGCGCGAGCTGCGGGGAACCGGCGCCAAGCACCTGGTTGCCGAGGATGGCG
ACGATGTGGCCGCATTCCTCAATTTGGTGGTGCCCGATGAGGCAGCCTCCGAGAACGCCACGGCGATGGCCGAATTGGTG
GTGGCGCCGGCCGCACGCCGCCGCGGGATCGGTTCGGCGATGGTGAGAGAAGCACTCGCCGAAGGTGGTGCGGGCACGCG
GGTCTGGGCTCACGGTGATCTACCTGCCGCCCAGTCGCTCGCCACGAAGCTGGGGCTGGTGGCGCTGCGACGGCTGCATC
AGATGCGGCGCGCATTGGCCGATCTGCCCGCGATACGCGTGGACGCCAGTGTCACGGTCCGGCACTACCTTGGGCCCCAA
GATGATTCGGACCTGCTGCGTGTCAACAATGCGGCGTTCTCCTGGCATCCGGAACAGGGTGGCTGGACACCAGGGGATCT
GGCCGACCGGTTTGCCGAACCCTGGTTCGACCCGCGGGGATTGTTCCTGGCGCATGACGTGCAGACCGCCAAGCTGCTCG
GGTTCCATTGGACCAAAAGGCATTTGGACAAGCCGGGCATGGGTGAGGTGTACATCGTGGGAGTGGACCCCGCCGCACAG
GGCCGAGGGCTGGGGCACCTACTGACCCTGGTGGGGTTGCATCACCTTGCCGGCCTCGGCCTGGAGACCGTGTTGCTGTA
CGTCGAATCGGACAATCAGGCGGCGTTGCGGACGTACGAGCGGCTGGGGTTTGCGGTGGCGCTCACCGATGCCGCCTACG
GTCGCGCCTGA

Upstream 100 bases:

>100_bases
TCCGATATCGACGATCTTGACGACGACGGTACCGATCAGGACATCGCCTCCGAACCGGGGGCGATCAACGCGGGGTGAAT
CTCCGACTAGCGTTGGCGGT

Downstream 100 bases:

>100_bases
CAGGGCGTTTACCTGCGATAACGACCGGACTGTCAAGTCTGTGAGTTCACTTCCCGTTCACCTGCGAGCGGGTGCCCGTC
CATCGACTGCCTTTAGTTTC

Product: putative acetyltransferase

Products: NA

Alternate protein names: MSH acetyltransferase; Mycothiol synthase

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGAKHLVAEDGDDVAAFLNLVVPDEAASENATAMAELV
VAPAARRRGIGSAMVREALAEGGAGTRVWAHGDLPAAQSLATKLGLVALRRLHQMRRALADLPAIRVDASVTVRHYLGPQ
DDSDLLRVNNAAFSWHPEQGGWTPGDLADRFAEPWFDPRGLFLAHDVQTAKLLGFHWTKRHLDKPGMGEVYIVGVDPAAQ
GRGLGHLLTLVGLHHLAGLGLETVLLYVESDNQAALRTYERLGFAVALTDAAYGRA

Sequences:

>Translated_296_residues
MTEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGAKHLVAEDGDDVAAFLNLVVPDEAASENATAMAELV
VAPAARRRGIGSAMVREALAEGGAGTRVWAHGDLPAAQSLATKLGLVALRRLHQMRRALADLPAIRVDASVTVRHYLGPQ
DDSDLLRVNNAAFSWHPEQGGWTPGDLADRFAEPWFDPRGLFLAHDVQTAKLLGFHWTKRHLDKPGMGEVYIVGVDPAAQ
GRGLGHLLTLVGLHHLAGLGLETVLLYVESDNQAALRTYERLGFAVALTDAAYGRA
>Mature_295_residues
TEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGAKHLVAEDGDDVAAFLNLVVPDEAASENATAMAELVV
APAARRRGIGSAMVREALAEGGAGTRVWAHGDLPAAQSLATKLGLVALRRLHQMRRALADLPAIRVDASVTVRHYLGPQD
DSDLLRVNNAAFSWHPEQGGWTPGDLADRFAEPWFDPRGLFLAHDVQTAKLLGFHWTKRHLDKPGMGEVYIVGVDPAAQG
RGLGHLLTLVGLHHLAGLGLETVLLYVESDNQAALRTYERLGFAVALTDAAYGRA

Specific function: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol

COG id: COG0456

COG function: function code R; Acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 N-acetyltransferase domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHD_MYCA9 (B1MI19)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001701495.1
- ProteinModelPortal:   B1MI19
- SMR:   B1MI19
- EnsemblBacteria:   EBMYCT00000005053
- GeneID:   5963279
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_0745
- GeneTree:   EBGT00050000016611
- HOGENOM:   HBG292446
- OMA:   GFHWTKI
- BioCyc:   MABS561007:MAB_0745-MONOMER
- HAMAP:   MF_01698
- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR017813
- Gene3D:   G3DSA:3.40.630.30
- TIGRFAMs:   TIGR03448

Pfam domain/function: PF00583 Acetyltransf_1; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.1.189

Molecular weight: Translated: 32021; Mature: 31890

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS51186 GNAT

Important sites: BINDING 34-34 BINDING 178-178 BINDING 219-219 BINDING 229-229 BINDING 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGAKHLVAEDGDDVAAFL
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHH
NLVVPDEAASENATAMAELVVAPAARRRGIGSAMVREALAEGGAGTRVWAHGDLPAAQSL
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHH
ATKLGLVALRRLHQMRRALADLPAIRVDASVTVRHYLGPQDDSDLLRVNNAAFSWHPEQG
HHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEECCCCCCCCCCEEECCCEEEEECCCC
GWTPGDLADRFAEPWFDPRGLFLAHDVQTAKLLGFHWTKRHLDKPGMGEVYIVGVDPAAQ
CCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
GRGLGHLLTLVGLHHLAGLGLETVLLYVESDNQAALRTYERLGFAVALTDAAYGRA
CCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHCEEEEEECHHCCCC
>Mature Secondary Structure 
TEWVPLLDNRRQLQIRELIVEATRADGIAPVGEQVLRELRGTGAKHLVAEDGDDVAAFL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHH
NLVVPDEAASENATAMAELVVAPAARRRGIGSAMVREALAEGGAGTRVWAHGDLPAAQSL
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHH
ATKLGLVALRRLHQMRRALADLPAIRVDASVTVRHYLGPQDDSDLLRVNNAAFSWHPEQG
HHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEECCCCCCCCCCEEECCCEEEEECCCC
GWTPGDLADRFAEPWFDPRGLFLAHDVQTAKLLGFHWTKRHLDKPGMGEVYIVGVDPAAQ
CCCCHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
GRGLGHLLTLVGLHHLAGLGLETVLLYVESDNQAALRTYERLGFAVALTDAAYGRA
CCCHHHHHHHHHHHHHHCCCHHHEEEEEECCCHHHHHHHHHHCEEEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA