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The map label for this gene is apeB [H]

Identifier: 169627803

GI number: 169627803

Start: 703255

End: 704523

Strand: Direct

Name: apeB [H]

Synonym: MAB_0701

Alternate gene names: 169627803

Gene position: 703255-704523 (Clockwise)

Preceding gene: 169627800

Following gene: 169627806

Centisome position: 13.88

GC content: 65.09

Gene sequence:

>1269_bases
GTGACCGCGACCGCAGTAGGACTTTGCCAATTCATCGACGCTTCGCCGTCCCCGTTCCATGCCGTGGACACGGTCGCGCA
GCGCCTGCGCCACGAGGGCTTTACCGAATTGTTCGAGGCGCAACGCTGGCCGGGCCACTCGGGGGACTACTTCGTGGTGC
GGTCGGGCTCGATCGTGGCCTGGCGCGGCGTTGACATGGAAGGCGAACACGCTGCCTTCCGGGTGATCGGAGCACATACC
GACAGCCCGAACCTGCGGGTGAAGGCCAACGCTGATCGCGTGCAGGCGGGGTGGCCGATGGTCGCCCTGGAGCCCTATGG
GGGCGCCTGGGTGCAAACCTGGTTGGACCGCGATCTGGGATTGTCCGGGCGCGTGCTGGTACGCGACGGAGATGCGGTGC
GCTCCACACTGATTCGGATCGATCAGCCGATTCTGCGGGTGCCGAACTTGGCGATTCACATGGTCAGTGCCGAGGAACGC
AAGAAATGGGTGATCGACCCGCAGTGGCATGTGAACTCGGTGTGGAGCGGTGAGCTCGGGTTCGAGGAGTACATCGCCGA
GCAGTTGGGCGTCAGCCCGGCCGATGTCCTTGGACGCGACCTGATGACACACGACCTGACCGGGGCAGCGCTGGTCGGAC
CCGACGAAAGTCTGCTCAGTGCCCCACGTTTGGATAACCAGGCCAGCTGTTATGCAGGTCTGGAGGCGTTCCTGGCGGCC
GAGTCCAGTTCGACGACGGTGCTGGCGCTTTTCGACCACGAGGAGGTCGGCTCGGTCTCCGACCACGGCGCCCACTCAGA
TCTACTCTCGACGGTTTTGGAGCGAATCGTGCTGTCCAGTAACGGAACCCGCGAGGACTTTCTGCGGCGTGCGGCTGCCT
CACTTATGGTCTCGGCCGACATGGCGCATGCGACCCATCCCAACTATCCGGATCGGCATGAACCCGGGCACCAGATCGCG
GTCAATGCCGGGCCGGTCATCAAGATCCACCCCAACGTCCGCTACGCCACCGACGGGCGGGGAGCGGCGGCCTTCGCCCT
GGCCTGTGAGCGGGCCGGGGTTCCCGTTCAGCGGTATGAACACCGGGCGGACATGCAGTGCGGATCCACCATTGGCCCGT
TCGCGGCATCGCACACCGGCATCACCACAGTGGATGTAGGCGCCGCGACCCTTGCCATGCACTCGGTGCGCGAACTGATG
GGCGCACACGACGTGCCGATGTACGCCGATGCGCTGCAGGCGTTTCTGGAGCTGCCCGCTACATCGTGA

Upstream 100 bases:

>100_bases
GAAAGATGGCCGAAGAGGACAGCGGTTCTAGGACGGCCTGCGGCACGGAATCGGGCACGCTTCGACCCTAGACCGTATTC
GGTCAGCCATCATGGGAAGC

Downstream 100 bases:

>100_bases
AACGCAGATTGGCGACGATCTTCCAGCCCAGGTCGGGATCGCCGTCAAGAGTGAATCCGTTGCGGTTGGCGCTGGCGCGC
CCGCCCAGATGACGGGCGAA

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MTATAVGLCQFIDASPSPFHAVDTVAQRLRHEGFTELFEAQRWPGHSGDYFVVRSGSIVAWRGVDMEGEHAAFRVIGAHT
DSPNLRVKANADRVQAGWPMVALEPYGGAWVQTWLDRDLGLSGRVLVRDGDAVRSTLIRIDQPILRVPNLAIHMVSAEER
KKWVIDPQWHVNSVWSGELGFEEYIAEQLGVSPADVLGRDLMTHDLTGAALVGPDESLLSAPRLDNQASCYAGLEAFLAA
ESSSTTVLALFDHEEVGSVSDHGAHSDLLSTVLERIVLSSNGTREDFLRRAAASLMVSADMAHATHPNYPDRHEPGHQIA
VNAGPVIKIHPNVRYATDGRGAAAFALACERAGVPVQRYEHRADMQCGSTIGPFAASHTGITTVDVGAATLAMHSVRELM
GAHDVPMYADALQAFLELPATS

Sequences:

>Translated_422_residues
MTATAVGLCQFIDASPSPFHAVDTVAQRLRHEGFTELFEAQRWPGHSGDYFVVRSGSIVAWRGVDMEGEHAAFRVIGAHT
DSPNLRVKANADRVQAGWPMVALEPYGGAWVQTWLDRDLGLSGRVLVRDGDAVRSTLIRIDQPILRVPNLAIHMVSAEER
KKWVIDPQWHVNSVWSGELGFEEYIAEQLGVSPADVLGRDLMTHDLTGAALVGPDESLLSAPRLDNQASCYAGLEAFLAA
ESSSTTVLALFDHEEVGSVSDHGAHSDLLSTVLERIVLSSNGTREDFLRRAAASLMVSADMAHATHPNYPDRHEPGHQIA
VNAGPVIKIHPNVRYATDGRGAAAFALACERAGVPVQRYEHRADMQCGSTIGPFAASHTGITTVDVGAATLAMHSVRELM
GAHDVPMYADALQAFLELPATS
>Mature_421_residues
TATAVGLCQFIDASPSPFHAVDTVAQRLRHEGFTELFEAQRWPGHSGDYFVVRSGSIVAWRGVDMEGEHAAFRVIGAHTD
SPNLRVKANADRVQAGWPMVALEPYGGAWVQTWLDRDLGLSGRVLVRDGDAVRSTLIRIDQPILRVPNLAIHMVSAEERK
KWVIDPQWHVNSVWSGELGFEEYIAEQLGVSPADVLGRDLMTHDLTGAALVGPDESLLSAPRLDNQASCYAGLEAFLAAE
SSSTTVLALFDHEEVGSVSDHGAHSDLLSTVLERIVLSSNGTREDFLRRAAASLMVSADMAHATHPNYPDRHEPGHQIAV
NAGPVIKIHPNVRYATDGRGAAAFALACERAGVPVQRYEHRADMQCGSTIGPFAASHTGITTVDVGAATLAMHSVRELMG
AHDVPMYADALQAFLELPATS

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=448, Percent_Identity=35.9375, Blast_Score=261, Evalue=6e-70,
Organism=Caenorhabditis elegans, GI17552916, Length=447, Percent_Identity=35.1230425055928, Blast_Score=233, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6321905, Length=459, Percent_Identity=34.4226579520697, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6322746, Length=453, Percent_Identity=28.6975717439294, Blast_Score=182, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 45572; Mature: 45440

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATAVGLCQFIDASPSPFHAVDTVAQRLRHEGFTELFEAQRWPGHSGDYFVVRSGSIVA
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCEEE
WRGVDMEGEHAAFRVIGAHTDSPNLRVKANADRVQAGWPMVALEPYGGAWVQTWLDRDLG
EECCCCCCCCEEEEEEECCCCCCCEEEEECCCEEECCCCEEEEECCCCHHHHHHHHHCCC
LSGRVLVRDGDAVRSTLIRIDQPILRVPNLAIHMVSAEERKKWVIDPQWHVNSVWSGELG
CCCEEEEECCHHHHHHHHHHCCCHHHCCCEEEEEEEHHCCCCEEECCCCCCCCEECCCCC
FEEYIAEQLGVSPADVLGRDLMTHDLTGAALVGPDESLLSAPRLDNQASCYAGLEAFLAA
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHHCC
ESSSTTVLALFDHEEVGSVSDHGAHSDLLSTVLERIVLSSNGTREDFLRRAAASLMVSAD
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MAHATHPNYPDRHEPGHQIAVNAGPVIKIHPNVRYATDGRGAAAFALACERAGVPVQRYE
HHHCCCCCCCCCCCCCCEEEECCCCEEEECCCEEEECCCCCHHHHHHHHHHCCCCHHHHH
HRADMQCGSTIGPFAASHTGITTVDVGAATLAMHSVRELMGAHDVPMYADALQAFLELPA
HHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
TS
CC
>Mature Secondary Structure 
TATAVGLCQFIDASPSPFHAVDTVAQRLRHEGFTELFEAQRWPGHSGDYFVVRSGSIVA
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEECCCEEE
WRGVDMEGEHAAFRVIGAHTDSPNLRVKANADRVQAGWPMVALEPYGGAWVQTWLDRDLG
EECCCCCCCCEEEEEEECCCCCCCEEEEECCCEEECCCCEEEEECCCCHHHHHHHHHCCC
LSGRVLVRDGDAVRSTLIRIDQPILRVPNLAIHMVSAEERKKWVIDPQWHVNSVWSGELG
CCCEEEEECCHHHHHHHHHHCCCHHHCCCEEEEEEEHHCCCCEEECCCCCCCCEECCCCC
FEEYIAEQLGVSPADVLGRDLMTHDLTGAALVGPDESLLSAPRLDNQASCYAGLEAFLAA
HHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHHCC
ESSSTTVLALFDHEEVGSVSDHGAHSDLLSTVLERIVLSSNGTREDFLRRAAASLMVSAD
CCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MAHATHPNYPDRHEPGHQIAVNAGPVIKIHPNVRYATDGRGAAAFALACERAGVPVQRYE
HHHCCCCCCCCCCCCCCEEEECCCCEEEECCCEEEECCCCCHHHHHHHHHHCCCCHHHHH
HRADMQCGSTIGPFAASHTGITTVDVGAATLAMHSVRELMGAHDVPMYADALQAFLELPA
HHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
TS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]