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The map label for this gene is purQ [H]

Identifier: 169627800

GI number: 169627800

Start: 700658

End: 701335

Strand: Direct

Name: purQ [H]

Synonym: MAB_0698

Alternate gene names: 169627800

Gene position: 700658-701335 (Clockwise)

Preceding gene: 169627799

Following gene: 169627803

Centisome position: 13.83

GC content: 67.99

Gene sequence:

>678_bases
ATGACCGCTCGCATCGGTGTCATCACCTTCCCCGGCACCCTTGACGACGTCGACGCCGCCCGCGCGGCCCGGCTCTCGGG
CGCCGAGGCGGTCTCGCTGTGGCATGACGATGCCGACCTGAAGTCCGTGGACGCCGTGATCGTGCCCGGCGGCTTCTCCT
ACGGTGACTACCTGCGTGCGGGGGCCATCGCGCGGTTCGCGCCGGTGATGCGCTCGGTGGTCGATGCTGCGGCGCAGGGG
TTGCCAATCCTGGGCATCTGCAATGGTTTCCAGGTGTTGTGCGAGGCCGGCCTGCTGCCGGGTGCGCTGACCCGCAATGC
CGGGCTGCACTTCGTATGCCGTGATGTATGGCTGGGTGTCGACGCCAACAACACCGCGTGGTCTTCGCGGTATGAGCGGG
ACGCCGACATCCTGGTGCCGCTGAAGTCCGGAGAGGGCCGCTACGTGGCCTCCGATGACGTTCTCGACGAGTTGGAGGGC
GAGGGCCGGGTGGTCTTCCGCTACCGCGAGAACCCCAACGGTTCGATGCGCGATATCGCCGGCATTTCCTCGGCCAACGG
CCGCGTGGTGGGGCTCATGCCGCACCCGGAGCACGCGACCGAGCCGTTGACCGGCCCCAGTGACGATGGACTCGGCATCT
TCTACTCGGCGCTGGATGCCGTCCTGACCGCGGGATAG

Upstream 100 bases:

>100_bases
AGTTCGACGGTGAGATCAGCGATTCCGATCTGGAGTCGATCGCCGAGGCGCTGCTCGCCAACACCGTCATCGAGGACTGG
GAAATCGTGCGGGAGTCCGA

Downstream 100 bases:

>100_bases
TACTCACCGAATGTCGACCTTCTGTTAAGAACTGCGAATGAACCGCCCCAAAGTCGACATTCGGCGAGAAGGGGACTAGG
GCAGCAGCGCGACCGATGCC

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTARIGVITFPGTLDDVDAARAARLSGAEAVSLWHDDADLKSVDAVIVPGGFSYGDYLRAGAIARFAPVMRSVVDAAAQG
LPILGICNGFQVLCEAGLLPGALTRNAGLHFVCRDVWLGVDANNTAWSSRYERDADILVPLKSGEGRYVASDDVLDELEG
EGRVVFRYRENPNGSMRDIAGISSANGRVVGLMPHPEHATEPLTGPSDDGLGIFYSALDAVLTAG

Sequences:

>Translated_225_residues
MTARIGVITFPGTLDDVDAARAARLSGAEAVSLWHDDADLKSVDAVIVPGGFSYGDYLRAGAIARFAPVMRSVVDAAAQG
LPILGICNGFQVLCEAGLLPGALTRNAGLHFVCRDVWLGVDANNTAWSSRYERDADILVPLKSGEGRYVASDDVLDELEG
EGRVVFRYRENPNGSMRDIAGISSANGRVVGLMPHPEHATEPLTGPSDDGLGIFYSALDAVLTAG
>Mature_224_residues
TARIGVITFPGTLDDVDAARAARLSGAEAVSLWHDDADLKSVDAVIVPGGFSYGDYLRAGAIARFAPVMRSVVDAAAQGL
PILGICNGFQVLCEAGLLPGALTRNAGLHFVCRDVWLGVDANNTAWSSRYERDADILVPLKSGEGRYVASDDVLDELEGE
GRVVFRYRENPNGSMRDIAGISSANGRVVGLMPHPEHATEPLTGPSDDGLGIFYSALDAVLTAG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=224, Percent_Identity=29.4642857142857, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321498, Length=184, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24582111, Length=203, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24582109, Length=203, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17137292, Length=203, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23716; Mature: 23585

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARIGVITFPGTLDDVDAARAARLSGAEAVSLWHDDADLKSVDAVIVPGGFSYGDYLRA
CCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHH
GAIARFAPVMRSVVDAAAQGLPILGICNGFQVLCEAGLLPGALTRNAGLHFVCRDVWLGV
HHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCHHCCCCCEEEEEEEEEEC
DANNTAWSSRYERDADILVPLKSGEGRYVASDDVLDELEGEGRVVFRYRENPNGSMRDIA
CCCCCCCCCCCCCCCEEEEEEECCCCCEEECCHHHHHHCCCCEEEEEEECCCCCCHHHHC
GISSANGRVVGLMPHPEHATEPLTGPSDDGLGIFYSALDAVLTAG
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TARIGVITFPGTLDDVDAARAARLSGAEAVSLWHDDADLKSVDAVIVPGGFSYGDYLRA
CCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCHHHHHHH
GAIARFAPVMRSVVDAAAQGLPILGICNGFQVLCEAGLLPGALTRNAGLHFVCRDVWLGV
HHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCHHCCCCCEEEEEEEEEEC
DANNTAWSSRYERDADILVPLKSGEGRYVASDDVLDELEGEGRVVFRYRENPNGSMRDIA
CCCCCCCCCCCCCCCEEEEEEECCCCCEEECCHHHHHHCCCCEEEEEEECCCCCCHHHHC
GISSANGRVVGLMPHPEHATEPLTGPSDDGLGIFYSALDAVLTAG
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]