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The map label for this gene is mhpF [C]

Identifier: 169627728

GI number: 169627728

Start: 624440

End: 625348

Strand: Direct

Name: mhpF [C]

Synonym: MAB_0625

Alternate gene names: 169627728

Gene position: 624440-625348 (Clockwise)

Preceding gene: 169627727

Following gene: 169627729

Centisome position: 12.32

GC content: 62.6

Gene sequence:

>909_bases
GTGGCGTCAAAGGCATCTGTAGCGATCGTCGGTTCGGGAAACATCAGCACCGACCTGCTGTACAAATTGCAGCGTTCCGA
GTGGCTGGAGCCGCGGTGGATGATCGGCATCGACCCCGAGTCCGAAGGTCTCAAGCGTGCCCGCGGTTTCGGTCTGGAAA
CCTCGCACGAGGGTGTGGACTGGTTGCTTGGGCAGGACGAGAAGCCGGATCTGGTCTTCGAGGCAACGTCCGCCTACGTG
CACAAGGCCGCCGCGCCACGCTATGAGGAAGCGGGCATCCGGGCCATCGATCTGACTCCCGCGGCGGTGGGACCAGCCGT
TGTGCCGCCCGCGAATCTGCGCGCCCACCTTGATGCTCCGAACGTCAACATGATCACCTGTGGTGGCCAGGCGACGATTC
CGATCGTGTACGCGGTGTCGCGCGTTGTCGAGGTGCCTTACGCCGAGATCGTCGCCTCGGTCGCCTCGGTGTCCGCAGGA
CCCGGAACGCGCGCCAACATCGACGAGTTCACCAAGACCACGTCCAAGGGGGTGGAGGTGATCGGAGGCGCCAAGCGCGG
AAAGGCGATCATCATCCTGAACCCCGCGGATCCGCCGATGATCATGCGCGACACAATTTTCTGCGCAATTCCTGAGGACG
CGGACCGTGCGGCGATTGCCGCGTCGATTCACGATGTGGTGAGCCAGGTTCAGCAGTACGTGCCCGGATACCGGCTGCTC
AATGAGCCGCAGTTCGATGAGCCGTCGGTGGTCAACGGCGGCAACCATGTCGTCACTACCTTCGTCGAGGTTGAGGGCGC
CGGTGACTTCTTGCCGCCGTATGCCGGAAACCTGGACATCATGACCGCGGCCGCGACCAAGGTCGGCGAGGAAATCGCCA
AAGAACTTCTATCTGCAAAGGTTTCGTGA

Upstream 100 bases:

>100_bases
TCGTGCACGCGGGCGTTCGACGCGCATCCGGGCGACGAGTTTTTAGCCGAGTTCGCCGGACTTGGTTCGGTCCGACTGGC
TTTCGAGTAGAGGAGAGATT

Downstream 100 bases:

>100_bases
AATGGGTTCGGACACCAGCACTCAGCTCTTGGGCACCGACGGCATCTTCTTCGACGCCGCATGGGACGTGCGGGTCACCG
ATACGTCGTTGCGTGATGGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 1

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MASKASVAIVGSGNISTDLLYKLQRSEWLEPRWMIGIDPESEGLKRARGFGLETSHEGVDWLLGQDEKPDLVFEATSAYV
HKAAAPRYEEAGIRAIDLTPAAVGPAVVPPANLRAHLDAPNVNMITCGGQATIPIVYAVSRVVEVPYAEIVASVASVSAG
PGTRANIDEFTKTTSKGVEVIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRAAIAASIHDVVSQVQQYVPGYRLL
NEPQFDEPSVVNGGNHVVTTFVEVEGAGDFLPPYAGNLDIMTAAATKVGEEIAKELLSAKVS

Sequences:

>Translated_302_residues
MASKASVAIVGSGNISTDLLYKLQRSEWLEPRWMIGIDPESEGLKRARGFGLETSHEGVDWLLGQDEKPDLVFEATSAYV
HKAAAPRYEEAGIRAIDLTPAAVGPAVVPPANLRAHLDAPNVNMITCGGQATIPIVYAVSRVVEVPYAEIVASVASVSAG
PGTRANIDEFTKTTSKGVEVIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRAAIAASIHDVVSQVQQYVPGYRLL
NEPQFDEPSVVNGGNHVVTTFVEVEGAGDFLPPYAGNLDIMTAAATKVGEEIAKELLSAKVS
>Mature_301_residues
ASKASVAIVGSGNISTDLLYKLQRSEWLEPRWMIGIDPESEGLKRARGFGLETSHEGVDWLLGQDEKPDLVFEATSAYVH
KAAAPRYEEAGIRAIDLTPAAVGPAVVPPANLRAHLDAPNVNMITCGGQATIPIVYAVSRVVEVPYAEIVASVASVSAGP
GTRANIDEFTKTTSKGVEVIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRAAIAASIHDVVSQVQQYVPGYRLLN
EPQFDEPSVVNGGNHVVTTFVEVEGAGDFLPPYAGNLDIMTAAATKVGEEIAKELLSAKVS

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=308, Percent_Identity=54.5454545454545, Blast_Score=307, Evalue=5e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH1_MYCA9 (B1MH39)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001701377.1
- EnsemblBacteria:   EBMYCT00000005639
- GeneID:   5963161
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_0625
- GeneTree:   EBGT00050000016468
- HOGENOM:   HBG300125
- OMA:   IGGAQRG
- ProtClustDB:   PRK08300
- BioCyc:   MABS561007:MAB_0625-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 31986; Mature: 31854

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: BINDING 277-277

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKASVAIVGSGNISTDLLYKLQRSEWLEPRWMIGIDPESEGLKRARGFGLETSHEGVD
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCC
WLLGQDEKPDLVFEATSAYVHKAAAPRYEEAGIRAIDLTPAAVGPAVVPPANLRAHLDAP
EECCCCCCCCEEEEHHHHHHHHHCCCCHHHCCCEEEECCCHHCCCCCCCCCCCEEEECCC
NVNMITCGGQATIPIVYAVSRVVEVPYAEIVASVASVSAGPGTRANIDEFTKTTSKGVEV
CCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEE
IGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRAAIAASIHDVVSQVQQYVPGYRLL
ECCCCCCCEEEEECCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEC
NEPQFDEPSVVNGGNHVVTTFVEVEGAGDFLPPYAGNLDIMTAAATKVGEEIAKELLSAK
CCCCCCCCCEECCCCEEEEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHC
VS
CC
>Mature Secondary Structure 
ASKASVAIVGSGNISTDLLYKLQRSEWLEPRWMIGIDPESEGLKRARGFGLETSHEGVD
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCC
WLLGQDEKPDLVFEATSAYVHKAAAPRYEEAGIRAIDLTPAAVGPAVVPPANLRAHLDAP
EECCCCCCCCEEEEHHHHHHHHHCCCCHHHCCCEEEECCCHHCCCCCCCCCCCEEEECCC
NVNMITCGGQATIPIVYAVSRVVEVPYAEIVASVASVSAGPGTRANIDEFTKTTSKGVEV
CCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEE
IGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRAAIAASIHDVVSQVQQYVPGYRLL
ECCCCCCCEEEEECCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEC
NEPQFDEPSVVNGGNHVVTTFVEVEGAGDFLPPYAGNLDIMTAAATKVGEEIAKELLSAK
CCCCCCCCCEECCCCEEEEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHC
VS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA