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The map label for this gene is fadE12 [H]

Identifier: 169627718

GI number: 169627718

Start: 614211

End: 615374

Strand: Direct

Name: fadE12 [H]

Synonym: MAB_0615

Alternate gene names: 169627718

Gene position: 614211-615374 (Clockwise)

Preceding gene: 169627717

Following gene: 169627719

Centisome position: 12.12

GC content: 61.77

Gene sequence:

>1164_bases
ATGCTAATTGACCTCACGCCGGAACAGGCGAAGCTACAAAATGATCTGCGGCACTACTTCTCGAATCTGGTGACCGCCGA
AGAGACCCGCGAGATGATGATCGACCGGCATGGTTCGTCCTATGAGGCCGTGGTGCGCCGCATGGGACAGGACGGCTGGT
TGGGAGTCGGTTGGCCCAAGGAATACGGTGGTCACGGATTCGGCCCGCTGGAACAGCAGATCTTCATGAACGAGGTCATG
CGTGCCGATGTGCCGATGCCACTGGTGACACTGCAGACCGTTGGTCCGACCCTGCAGAAGTACGGTACCGAGGAGCAGAA
AAAGAAGTTTCTGCCGGGAATCCTCGCCGGTGAAATCCATTTCGCCATCGGGTACACCGAACCGGAGGCCGGAACCGACC
TCGCATCCTTGCGCACCACGGCGGTGCGCGACGGCGATCACTACGTCGTCAATGGGCAGAAGATCTTCACCACCGGTGCG
CATCAGGCGCAGTACATCTGGCTGGCCTGCCGCACCGACCCGAGCGCCCCTAAACACAAGGGCATCTCGATTCTCATCGT
CGACACCAAGGATCCGGGCTATTCGTGGACCCCGATCATCACCAATGACGGCGCGCACCACACCAATGCCACCTATTACA
CCGATGTGCGGGTTCCGGTGGAAATGCTGGTGGGCGAGGAAAACGCGGGCTGGAAGCTCATCACGACCCAGCTGAACCAT
GAGCGGGTCTCGCTCGGCCCGTCCGGGCGGATCGCGGGCATGTACGACCGCGTGTACGAGTGGGCGTCCAAGCCGGGGCC
GGACGGTGTGGCGCCGTTGTCGCATGAGGATGTGCGCCGGGTGCTGGGCGAGATGAAGGCCGTGTGGCGGCTCAACGAGT
TGCTCAACTGGCAGGTCGCGTCATCGGGCGACGACATCAGCATGGCCGATGCCGCTGCGACGAAGATCCTTGCCACTGAA
TGGATTCAGAAACTCGGACGACTGAGCGAGGGTGTGGTCGGGCGCTATGGCGATCCCGCTGACGCGAATACCGCGGAGAC
TCTCGAATGGCTTGATGCACAGACCAAACGCCACCTGGTGATCACCTTCGGTGGCGGCGTGAACGAGGTGATGCGCGAGA
TGGTGTCGACGGCAGGATTGGGCACGCCGAGGGTTCCGCGATGA

Upstream 100 bases:

>100_bases
GAATCGTTACTACTCGACGATCAAGGATCTGAGCCGTCTGGTCGGCGGGTCCTCCGAGCGCCTAGACGTCCTTGCCGCGG
CGCAGGGTTAGGAGCCAGCG

Downstream 100 bases:

>100_bases
GCGTGGTGGACATCCAGGAGGGTTTCGCCAAGATCAAGGCCGACGGCCCGAGCGCGCCCCGCCTGGCACGGGATCCGGTG
AACCAGGCGATGATCAACAA

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLIDLTPEQAKLQNDLRHYFSNLVTAEETREMMIDRHGSSYEAVVRRMGQDGWLGVGWPKEYGGHGFGPLEQQIFMNEVM
RADVPMPLVTLQTVGPTLQKYGTEEQKKKFLPGILAGEIHFAIGYTEPEAGTDLASLRTTAVRDGDHYVVNGQKIFTTGA
HQAQYIWLACRTDPSAPKHKGISILIVDTKDPGYSWTPIITNDGAHHTNATYYTDVRVPVEMLVGEENAGWKLITTQLNH
ERVSLGPSGRIAGMYDRVYEWASKPGPDGVAPLSHEDVRRVLGEMKAVWRLNELLNWQVASSGDDISMADAAATKILATE
WIQKLGRLSEGVVGRYGDPADANTAETLEWLDAQTKRHLVITFGGGVNEVMREMVSTAGLGTPRVPR

Sequences:

>Translated_387_residues
MLIDLTPEQAKLQNDLRHYFSNLVTAEETREMMIDRHGSSYEAVVRRMGQDGWLGVGWPKEYGGHGFGPLEQQIFMNEVM
RADVPMPLVTLQTVGPTLQKYGTEEQKKKFLPGILAGEIHFAIGYTEPEAGTDLASLRTTAVRDGDHYVVNGQKIFTTGA
HQAQYIWLACRTDPSAPKHKGISILIVDTKDPGYSWTPIITNDGAHHTNATYYTDVRVPVEMLVGEENAGWKLITTQLNH
ERVSLGPSGRIAGMYDRVYEWASKPGPDGVAPLSHEDVRRVLGEMKAVWRLNELLNWQVASSGDDISMADAAATKILATE
WIQKLGRLSEGVVGRYGDPADANTAETLEWLDAQTKRHLVITFGGGVNEVMREMVSTAGLGTPRVPR
>Mature_387_residues
MLIDLTPEQAKLQNDLRHYFSNLVTAEETREMMIDRHGSSYEAVVRRMGQDGWLGVGWPKEYGGHGFGPLEQQIFMNEVM
RADVPMPLVTLQTVGPTLQKYGTEEQKKKFLPGILAGEIHFAIGYTEPEAGTDLASLRTTAVRDGDHYVVNGQKIFTTGA
HQAQYIWLACRTDPSAPKHKGISILIVDTKDPGYSWTPIITNDGAHHTNATYYTDVRVPVEMLVGEENAGWKLITTQLNH
ERVSLGPSGRIAGMYDRVYEWASKPGPDGVAPLSHEDVRRVLGEMKAVWRLNELLNWQVASSGDDISMADAAATKILATE
WIQKLGRLSEGVVGRYGDPADANTAETLEWLDAQTKRHLVITFGGGVNEVMREMVSTAGLGTPRVPR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=260, Percent_Identity=29.2307692307692, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226958414, Length=219, Percent_Identity=31.9634703196347, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI4501857, Length=384, Percent_Identity=25.2604166666667, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI7656849, Length=361, Percent_Identity=26.5927977839335, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4557231, Length=353, Percent_Identity=26.9121813031161, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI187960098, Length=353, Percent_Identity=26.9121813031161, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI21361497, Length=248, Percent_Identity=29.0322580645161, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4557233, Length=315, Percent_Identity=27.6190476190476, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501859, Length=233, Percent_Identity=26.6094420600858, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI76496475, Length=347, Percent_Identity=25.9365994236311, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557235, Length=347, Percent_Identity=25.9365994236311, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38505218, Length=262, Percent_Identity=26.7175572519084, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI48976061, Length=300, Percent_Identity=27.3333333333333, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI211971008, Length=300, Percent_Identity=27.3333333333333, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI87081958, Length=394, Percent_Identity=25.6345177664975, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786223, Length=297, Percent_Identity=25.2525252525253, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=342, Percent_Identity=26.6081871345029, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17534899, Length=334, Percent_Identity=26.9461077844311, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=356, Percent_Identity=26.4044943820225, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=263, Percent_Identity=30.7984790874525, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=331, Percent_Identity=26.5861027190332, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=363, Percent_Identity=24.2424242424242, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=212, Percent_Identity=32.5471698113208, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=275, Percent_Identity=25.4545454545455, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=352, Percent_Identity=24.7159090909091, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=348, Percent_Identity=23.8505747126437, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=264, Percent_Identity=26.1363636363636, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=326, Percent_Identity=24.2331288343558, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=298, Percent_Identity=26.510067114094, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=214, Percent_Identity=30.3738317757009, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281363737, Length=339, Percent_Identity=27.1386430678466, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21355753, Length=225, Percent_Identity=31.5555555555556, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356377, Length=345, Percent_Identity=27.536231884058, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24646207, Length=309, Percent_Identity=28.8025889967638, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24666513, Length=226, Percent_Identity=30.0884955752212, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24660351, Length=311, Percent_Identity=27.3311897106109, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42825; Mature: 42825

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDLTPEQAKLQNDLRHYFSNLVTAEETREMMIDRHGSSYEAVVRRMGQDGWLGVGWPK
CEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEECCCCH
EYGGHGFGPLEQQIFMNEVMRADVPMPLVTLQTVGPTLQKYGTEEQKKKFLPGILAGEIH
HHCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCHHHHHHCCHHHHHHHCCCEEECEEE
FAIGYTEPEAGTDLASLRTTAVRDGDHYVVNGQKIFTTGAHQAQYIWLACRTDPSAPKHK
EEEECCCCCCCCCHHHHHHHHEECCCEEEECCCEEEEECCCCEEEEEEEEECCCCCCCCC
GISILIVDTKDPGYSWTPIITNDGAHHTNATYYTDVRVPVEMLVGEENAGWKLITTQLNH
CEEEEEEECCCCCCEECCEEECCCCCCCCCEEEEEECCEEEEEECCCCCCEEEEEEECCC
ERVSLGPSGRIAGMYDRVYEWASKPGPDGVAPLSHEDVRRVLGEMKAVWRLNELLNWQVA
CEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEE
SSGDDISMADAAATKILATEWIQKLGRLSEGVVGRYGDPADANTAETLEWLDAQTKRHLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
ITFGGGVNEVMREMVSTAGLGTPRVPR
EEECCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLIDLTPEQAKLQNDLRHYFSNLVTAEETREMMIDRHGSSYEAVVRRMGQDGWLGVGWPK
CEEECCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEECCCCH
EYGGHGFGPLEQQIFMNEVMRADVPMPLVTLQTVGPTLQKYGTEEQKKKFLPGILAGEIH
HHCCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHCCHHHHHHCCHHHHHHHCCCEEECEEE
FAIGYTEPEAGTDLASLRTTAVRDGDHYVVNGQKIFTTGAHQAQYIWLACRTDPSAPKHK
EEEECCCCCCCCCHHHHHHHHEECCCEEEECCCEEEEECCCCEEEEEEEEECCCCCCCCC
GISILIVDTKDPGYSWTPIITNDGAHHTNATYYTDVRVPVEMLVGEENAGWKLITTQLNH
CEEEEEEECCCCCCEECCEEECCCCCCCCCEEEEEECCEEEEEECCCCCCEEEEEEECCC
ERVSLGPSGRIAGMYDRVYEWASKPGPDGVAPLSHEDVRRVLGEMKAVWRLNELLNWQVA
CEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEE
SSGDDISMADAAATKILATEWIQKLGRLSEGVVGRYGDPADANTAETLEWLDAQTKRHLV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
ITFGGGVNEVMREMVSTAGLGTPRVPR
EEECCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]