| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is gdhII [H]
Identifier: 169627710
GI number: 169627710
Start: 606400
End: 607182
Strand: Direct
Name: gdhII [H]
Synonym: MAB_0607
Alternate gene names: 169627710
Gene position: 606400-607182 (Clockwise)
Preceding gene: 169627704
Following gene: 169627711
Centisome position: 11.97
GC content: 66.28
Gene sequence:
>783_bases GTGCGAACCCCCTATGACCTCGGCCTTGAGGGTCGCGTCGTCCTCGTTACCGGCGGCGTCCGCGGGGTCGGTGCCGGAAT CAGCCAGGTTTTCGCCGACCAGGGTGCGACGGTGGTGACTTGCGCGCGCCGGCCCGGTGACGCTCCTTACGAGTTCCACT CCTGCGATGTGCGCGACGAAGAGTCGGTGGACACGCTCATCGGCGCCATCGTCGCCGCGCATGGTCGCCTGGACGCCGTG GTGAACAACGCGGGGGGCGCACCCTTCGCGCTCGCTGCCGATGCGAGTCACAATTTCCATCGCAAGATCATCGAGTTGAA CCTGCTCTCTGCCCTGCTGGTCTCTCAGCGTGCCAACGCGGTGATGCAGAAGCAGGACGGCGGCGGCACGATCGTCAACA TCACCAGCGTCAGCGCGGGCCGTCCGTCGCCGGGTACCGCCGCCTACGGCGCTGCCAAGGCCGGGCTGGAGAGCCTGACC CGGAGTCTGGCCGTCGAATGGGCACCCAAGGTACGGGTGAATGCCCTCGCCGCGGGGATGATCCGTACCGAGCTCTCGGA GATGCACTACGGCGACGAAGACGGGATTGCTGCGGTGGGCGCTACCGTACCGCTCGGGCGCCTGGCCAACCCGGACGAGA TCGGTTGGACCGCGGCATTCCTAGCATCACCACTGTCTTCGTATGTGACCGGTTCGGTCCTCACGGTTCACGGCGGAGGG GAGCGTCCGGCGTTCCTCGACGCGGCCAATGTCAACAGCAATGAGAACGGCGAAAAGGAATAG
Upstream 100 bases:
>100_bases GCCCATGAGACTCCTCAAGGTACCGAAACAAGCACTTGCTTGGTACGCTACCATGGCTCGAAAGCGCAGGACAAACAGCA GGAACAGGGCAAGGAGTCAC
Downstream 100 bases:
>100_bases AACATGCCAGGTTTACTCGACGGTCGGGTCGTCATCATCACGGGCGCGGGCCGTGGCATCGGCCGGGCGCACGCACTGGC GTTCGCCGCAGAAGGGGCGC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: GLCDH-II [H]
Number of amino acids: Translated: 260; Mature: 260
Protein sequence:
>260_residues MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVTCARRPGDAPYEFHSCDVRDEESVDTLIGAIVAAHGRLDAV VNNAGGAPFALAADASHNFHRKIIELNLLSALLVSQRANAVMQKQDGGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLT RSLAVEWAPKVRVNALAAGMIRTELSEMHYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHGGG ERPAFLDAANVNSNENGEKE
Sequences:
>Translated_260_residues MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVTCARRPGDAPYEFHSCDVRDEESVDTLIGAIVAAHGRLDAV VNNAGGAPFALAADASHNFHRKIIELNLLSALLVSQRANAVMQKQDGGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLT RSLAVEWAPKVRVNALAAGMIRTELSEMHYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHGGG ERPAFLDAANVNSNENGEKE >Mature_260_residues MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVTCARRPGDAPYEFHSCDVRDEESVDTLIGAIVAAHGRLDAV VNNAGGAPFALAADASHNFHRKIIELNLLSALLVSQRANAVMQKQDGGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLT RSLAVEWAPKVRVNALAAGMIRTELSEMHYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHGGG ERPAFLDAANVNSNENGEKE
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=31.8367346938775, Blast_Score=124, Evalue=7e-29, Organism=Homo sapiens, GI19923817, Length=271, Percent_Identity=29.1512915129151, Blast_Score=115, Evalue=5e-26, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=33.8645418326693, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=29.3172690763052, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI59889578, Length=230, Percent_Identity=33.0434782608696, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.9180327868852, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=31.5126050420168, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=29.3172690763052, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI4503301, Length=191, Percent_Identity=29.3193717277487, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=27.5590551181102, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=29.7872340425532, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=29.8507462686567, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI109715829, Length=237, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI224922801, Length=175, Percent_Identity=30.2857142857143, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=27.5590551181102, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI302344755, Length=114, Percent_Identity=34.2105263157895, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=34.4961240310078, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=35.2459016393443, Blast_Score=109, Evalue=1e-25, Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=32.8125, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1789208, Length=249, Percent_Identity=30.5220883534137, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI1788459, Length=166, Percent_Identity=39.7590361445783, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=31.5573770491803, Blast_Score=94, Evalue=8e-21, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=28.1124497991968, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=31.4516129032258, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=30.241935483871, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=26.9387755102041, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=29.957805907173, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1787545, Length=247, Percent_Identity=28.3400809716599, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787820, Length=201, Percent_Identity=28.8557213930348, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787526, Length=206, Percent_Identity=26.2135922330097, Blast_Score=62, Evalue=4e-11, Organism=Escherichia coli, GI1789057, Length=195, Percent_Identity=28.7179487179487, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=32.1428571428571, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=33.6065573770492, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=31.9230769230769, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=28.4584980237154, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=28.735632183908, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17561272, Length=255, Percent_Identity=32.9411764705882, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=29.8039215686275, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=29.1512915129151, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=28.0769230769231, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI72000259, Length=277, Percent_Identity=27.0758122743682, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=29.0196078431373, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=27.5471698113208, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=29.4339622641509, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=30, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=27.2357723577236, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=28.3018867924528, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=28.4615384615385, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=26.8, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=27.9245283018868, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.4615384615385, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=24.1758241758242, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=26.865671641791, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=23.5074626865672, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=26.4367816091954, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=227, Percent_Identity=31.2775330396476, Blast_Score=90, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=23.5897435897436, Blast_Score=67, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6322226, Length=189, Percent_Identity=29.1005291005291, Blast_Score=62, Evalue=7e-11, Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=32.1285140562249, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=33.0677290836653, Blast_Score=103, Evalue=8e-23, Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=28.9795918367347, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.0813008130081, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=31.25, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI24644337, Length=254, Percent_Identity=31.1023622047244, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=32.2448979591837, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=29.4820717131474, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI116007236, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24580925, Length=207, Percent_Identity=27.536231884058, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=24.6231155778894, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.47 [H]
Molecular weight: Translated: 26773; Mature: 26773
Theoretical pI: Translated: 5.09; Mature: 5.09
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVTCARRPGDAPYEFHSCDVRDE CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCC ESVDTLIGAIVAAHGRLDAVVNNAGGAPFALAADASHNFHRKIIELNLLSALLVSQRANA HHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH VMQKQDGGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLTRSLAVEWAPKVRVNALAAGM HEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH IRTELSEMHYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHGGG HHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCC ERPAFLDAANVNSNENGEKE CCCCEEEECCCCCCCCCCCC >Mature Secondary Structure MRTPYDLGLEGRVVLVTGGVRGVGAGISQVFADQGATVVTCARRPGDAPYEFHSCDVRDE CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCC ESVDTLIGAIVAAHGRLDAVVNNAGGAPFALAADASHNFHRKIIELNLLSALLVSQRANA HHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH VMQKQDGGGTIVNITSVSAGRPSPGTAAYGAAKAGLESLTRSLAVEWAPKVRVNALAAGM HEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH IRTELSEMHYGDEDGIAAVGATVPLGRLANPDEIGWTAAFLASPLSSYVTGSVLTVHGGG HHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCC ERPAFLDAANVNSNENGEKE CCCCEEEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA