| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is fabG2 [H]
Identifier: 169627701
GI number: 169627701
Start: 599420
End: 600208
Strand: Direct
Name: fabG2 [H]
Synonym: MAB_0598
Alternate gene names: 169627701
Gene position: 599420-600208 (Clockwise)
Preceding gene: 169627700
Following gene: 169627702
Centisome position: 11.83
GC content: 67.3
Gene sequence:
>789_bases ATGAACCTGGCAGAGGCGCCGACAGAGATCGAGGGCCATGGCCTCCTGAAGGGCAAGGCCGTCGTCGTGACCGCAGCGGC CGGCACCGGAATCGGCTCGTCGACCGCGCGGCGGGCACTGGTCGAGGGTGCCGACGTGGTCGTCTCCGACTATCACGAGC GTCGCCTGACCGAGACGCGGGACGAACTCGCCGCGCTAGGGCTCGGCAAGGTCGCGGCGGTGGTGTGCGATGTCACCTCT ACCGAGGCGGTCGACGCATTGATCACAGAATCCGTTGCGGCCCTGGGCCGTATCGATGTGCTGGTGAACAATGCGGGCCT TGGTGGAGAGACTCCGGTCGCCGATATGACCGACGACCAGTGGGACAGGGTGCTCGATGTGACCCTCACCTCGACTTTCC GGGCGACCCGTGCGGCCCTGCGCTATTTCCGCGAGGCGGGCCACGGCGGGGTGATCGTCAACAACGCGAGCGTGTTGGGC TGGCGCGCGCAATACGGACAGTCGCACTATGCCGCCGCCAAGGCCGGCGTCATGGCCCTGACTCGCTGCAGTGCCATCGA GGCCGTCGAGCACGGGGTGCGCGTCAACGCGGTCGCTCCGAGCATCGCTCGGCACAAGTTCCTCGACAAGGTGACTTCCT CGGACCTGCTGGACAAACTGTCCTCCGACGAGGCCTTCGGCCGCGCTGCCGAGCCGTGGGAGGTCGCGGCCACCATCGCC TTCCTGGCCAGCGACTATTCGAGCTACCTGACCGGCGAGGTCATCTCGGTATCCAGCCAGCGGGCGTGA
Upstream 100 bases:
>100_bases CCTGTTTTCTCGTGCTGACACCATCTACGGCGGATCCAATGAGATCCAGCGCAACATCATCTCCGAGCGGGTGCTCGGTC TACCCAGAGAGGCTCGCTAA
Downstream 100 bases:
>100_bases CATCGCGCACGCGTTCGACCAAACAAGCGCTTGGTTGATACAGTGAGGAGGTGGACAAGGTGTCAGAGGTGCGAGAGTCG GACGCACTGCGCGCGGGCGG
Product: short chain dehydrogenase
Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 262; Mature: 262
Protein sequence:
>262_residues MNLAEAPTEIEGHGLLKGKAVVVTAAAGTGIGSSTARRALVEGADVVVSDYHERRLTETRDELAALGLGKVAAVVCDVTS TEAVDALITESVAALGRIDVLVNNAGLGGETPVADMTDDQWDRVLDVTLTSTFRATRAALRYFREAGHGGVIVNNASVLG WRAQYGQSHYAAAKAGVMALTRCSAIEAVEHGVRVNAVAPSIARHKFLDKVTSSDLLDKLSSDEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSSQRA
Sequences:
>Translated_262_residues MNLAEAPTEIEGHGLLKGKAVVVTAAAGTGIGSSTARRALVEGADVVVSDYHERRLTETRDELAALGLGKVAAVVCDVTS TEAVDALITESVAALGRIDVLVNNAGLGGETPVADMTDDQWDRVLDVTLTSTFRATRAALRYFREAGHGGVIVNNASVLG WRAQYGQSHYAAAKAGVMALTRCSAIEAVEHGVRVNAVAPSIARHKFLDKVTSSDLLDKLSSDEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSSQRA >Mature_262_residues MNLAEAPTEIEGHGLLKGKAVVVTAAAGTGIGSSTARRALVEGADVVVSDYHERRLTETRDELAALGLGKVAAVVCDVTS TEAVDALITESVAALGRIDVLVNNAGLGGETPVADMTDDQWDRVLDVTLTSTFRATRAALRYFREAGHGGVIVNNASVLG WRAQYGQSHYAAAKAGVMALTRCSAIEAVEHGVRVNAVAPSIARHKFLDKVTSSDLLDKLSSDEAFGRAAEPWEVAATIA FLASDYSSYLTGEVISVSSQRA
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=246, Percent_Identity=34.1463414634146, Blast_Score=121, Evalue=6e-28, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=30.6201550387597, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=31.8725099601594, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI10190704, Length=276, Percent_Identity=28.6231884057971, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=30.3149606299213, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=29.7560975609756, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI4504505, Length=221, Percent_Identity=30.316742081448, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=30.0448430493274, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=30.4347826086957, Blast_Score=89, Evalue=6e-18, Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=32.258064516129, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=29.4354838709677, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=29.3650793650794, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=30.635838150289, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI66933014, Length=250, Percent_Identity=27.6, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI33667109, Length=201, Percent_Identity=30.8457711442786, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=29.6442687747036, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=215, Percent_Identity=25.1162790697674, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40254986, Length=203, Percent_Identity=28.0788177339901, Blast_Score=68, Evalue=1e-11, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=34.0080971659919, Blast_Score=127, Evalue=6e-31, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=32.2709163346614, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=35.2226720647773, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=32.0987654320988, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=28.6274509803922, Blast_Score=98, Evalue=4e-22, Organism=Escherichia coli, GI1788459, Length=239, Percent_Identity=30.1255230125523, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=28.4, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=29.8804780876494, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=25.1012145748988, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.0836653386454, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=28.6290322580645, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=28.4153005464481, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1789057, Length=250, Percent_Identity=26.4, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=32.2709163346614, Blast_Score=125, Evalue=2e-29, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=34.6456692913386, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=33.8775510204082, Blast_Score=123, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=34.251968503937, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=33.0612244897959, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=32.8063241106719, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.4516129032258, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=31.5589353612167, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.1787072243346, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17560332, Length=253, Percent_Identity=33.201581027668, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=30.3846153846154, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=31.3953488372093, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=30.7984790874525, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=31.25, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=30, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17551412, Length=256, Percent_Identity=32.03125, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=31.1284046692607, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=30.3149606299213, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=29.1828793774319, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=30.078125, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=31.1475409836066, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17568967, Length=213, Percent_Identity=28.169014084507, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17563726, Length=252, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17565030, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17536651, Length=252, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17544670, Length=249, Percent_Identity=27.3092369477912, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=27.5590551181102, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=28.2786885245902, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=28.1914893617021, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561272, Length=224, Percent_Identity=27.2321428571429, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=224, Percent_Identity=31.25, Blast_Score=99, Evalue=7e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=30.6532663316583, Blast_Score=62, Evalue=8e-11, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=35.4581673306773, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=34.2629482071713, Blast_Score=119, Evalue=1e-27, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=33.1983805668016, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=32.9317269076305, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=31.6, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=32.3886639676113, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI18859837, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=29.3877551020408, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=30.5882352941176, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI24644337, Length=170, Percent_Identity=34.7058823529412, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI24665243, Length=215, Percent_Identity=30.6976744186047, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI221331218, Length=215, Percent_Identity=30.6976744186047, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24665247, Length=216, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI221331216, Length=216, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24641232, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364892, Length=160, Percent_Identity=30, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100
Molecular weight: Translated: 27458; Mature: 27458
Theoretical pI: Translated: 4.99; Mature: 4.99
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNLAEAPTEIEGHGLLKGKAVVVTAAAGTGIGSSTARRALVEGADVVVSDYHERRLTETR CCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH DELAALGLGKVAAVVCDVTSTEAVDALITESVAALGRIDVLVNNAGLGGETPVADMTDDQ HHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCH WDRVLDVTLTSTFRATRAALRYFREAGHGGVIVNNASVLGWRAQYGQSHYAAAKAGVMAL HHHEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEHHHHCCCHHHHHHHHHHHH TRCSAIEAVEHGVRVNAVAPSIARHKFLDKVTSSDLLDKLSSDEAFGRAAEPWEVAATIA HHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHH FLASDYSSYLTGEVISVSSQRA HHHHHHHHHHCCHHEECCCCCC >Mature Secondary Structure MNLAEAPTEIEGHGLLKGKAVVVTAAAGTGIGSSTARRALVEGADVVVSDYHERRLTETR CCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH DELAALGLGKVAAVVCDVTSTEAVDALITESVAALGRIDVLVNNAGLGGETPVADMTDDQ HHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCH WDRVLDVTLTSTFRATRAALRYFREAGHGGVIVNNASVLGWRAQYGQSHYAAAKAGVMAL HHHEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEHHHHCCCHHHHHHHHHHHH TRCSAIEAVEHGVRVNAVAPSIARHKFLDKVTSSDLLDKLSSDEAFGRAAEPWEVAATIA HHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHH FLASDYSSYLTGEVISVSSQRA HHHHHHHHHHCCHHEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+
Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]