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The map label for this gene is yfhQ [H]

Identifier: 169627661

GI number: 169627661

Start: 559115

End: 559957

Strand: Reverse

Name: yfhQ [H]

Synonym: MAB_0558c

Alternate gene names: 169627661

Gene position: 559957-559115 (Counterclockwise)

Preceding gene: 169627665

Following gene: 169627657

Centisome position: 11.05

GC content: 67.5

Gene sequence:

>843_bases
TTGGGCTGGTTCGATGTTGCCGAACGGGATCTGCCGTGGCGCCGGCCCGAGGCGACACCGTGGCACATCCTCATCAGCGA
GGTGATGCTGCAGCAAACGCCCGTGTCCCGGGTCGAGCCGGTGTGGCGCGAATGGGTAGCGCGGTGGCCGGTTCCGTCCG
CGATGGCGAAAACCTCTGTGGCAGAGGTCTTACGCGCATGGGGAAAGCTCGGCTATCCCCGCCGCGCCATGCGTCTGCAC
GAGTGCGCGACGGTACTGGCCCGCGACTACGACGACCAGGTGCCCGGCGACGTAGAGACCCTCTTGACACTCCCCGGCGT
CGGCGCTTATACGGCTCGCGCCATCGCCTGTTTCGGATACGGACAGCGAGTTCCTGTGGTGGACACCAATGTTCGCCGCG
TCATCGCAAGGGTGGTGCACGGCGTCGCCGACTCGGCGCCCTCGGCACGCGACCTGCGCGACGCCGAGGCACTATTACCA
ACAGAGAACGGTGCCCGCTTTTCGGCGGCACTCATGGAGTTGGGCGCCCTGGTATGCACGGCCCGCACCCCGCAATGCCC
GATGTGTCCGCTGAGCTCTTGCGCATGGCATGAGGCGGGCCAGCCCCCGCTGGATGCCCCGGCACGCCCCGTACAGAAAT
ACGCCGGTACCGATCGTCAGGTGCGTGGGCGGCTACTGGATGTTCTGCGCGGCAGCAGCATTCCGGTGACGAGGGCCCAA
CTCGACGTGGCGTGGCTCTCCGATATCACGCAGCGTGACCGGGCGCTGGATTCGCTTCTGGTCGACGGGCTGGTGGAACA
GACGGCAGACGGCCGGTTCGCGCTGGCCGGCGAGGGCGGCTAG

Upstream 100 bases:

>100_bases
TGCGGAAAACCCCCGACAAAACGCTGGTTACCCTCTTTGAGTGCCTTCCAGGCGGACTTCGGATCAGATGCCATACCCGA
CATTGTGCCCTGAGGAACTT

Downstream 100 bases:

>100_bases
CGCGCGGCTACCGCAAAGGCCTTGCGGTAATCGGTGGGCGTGATGCCCACACCGCGCCGGAAGTGATGGCGCAACAAGAT
CGCGGTGCCAAAACCGCTGC

Product: adenine glycosylase MutY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MGWFDVAERDLPWRRPEATPWHILISEVMLQQTPVSRVEPVWREWVARWPVPSAMAKTSVAEVLRAWGKLGYPRRAMRLH
ECATVLARDYDDQVPGDVETLLTLPGVGAYTARAIACFGYGQRVPVVDTNVRRVIARVVHGVADSAPSARDLRDAEALLP
TENGARFSAALMELGALVCTARTPQCPMCPLSSCAWHEAGQPPLDAPARPVQKYAGTDRQVRGRLLDVLRGSSIPVTRAQ
LDVAWLSDITQRDRALDSLLVDGLVEQTADGRFALAGEGG

Sequences:

>Translated_280_residues
MGWFDVAERDLPWRRPEATPWHILISEVMLQQTPVSRVEPVWREWVARWPVPSAMAKTSVAEVLRAWGKLGYPRRAMRLH
ECATVLARDYDDQVPGDVETLLTLPGVGAYTARAIACFGYGQRVPVVDTNVRRVIARVVHGVADSAPSARDLRDAEALLP
TENGARFSAALMELGALVCTARTPQCPMCPLSSCAWHEAGQPPLDAPARPVQKYAGTDRQVRGRLLDVLRGSSIPVTRAQ
LDVAWLSDITQRDRALDSLLVDGLVEQTADGRFALAGEGG
>Mature_279_residues
GWFDVAERDLPWRRPEATPWHILISEVMLQQTPVSRVEPVWREWVARWPVPSAMAKTSVAEVLRAWGKLGYPRRAMRLHE
CATVLARDYDDQVPGDVETLLTLPGVGAYTARAIACFGYGQRVPVVDTNVRRVIARVVHGVADSAPSARDLRDAEALLPT
ENGARFSAALMELGALVCTARTPQCPMCPLSSCAWHEAGQPPLDAPARPVQKYAGTDRQVRGRLLDVLRGSSIPVTRAQL
DVAWLSDITQRDRALDSLLVDGLVEQTADGRFALAGEGG

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal effici

COG id: COG1194

COG function: function code L; A/G-specific DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HhH domain [H]

Homologues:

Organism=Homo sapiens, GI115298650, Length=206, Percent_Identity=39.8058252427184, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI115298654, Length=206, Percent_Identity=39.8058252427184, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI115298652, Length=206, Percent_Identity=39.8058252427184, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI6912520, Length=206, Percent_Identity=39.8058252427184, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI115298648, Length=206, Percent_Identity=39.8058252427184, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI190358497, Length=206, Percent_Identity=39.8058252427184, Blast_Score=127, Evalue=8e-30,
Organism=Escherichia coli, GI1789331, Length=199, Percent_Identity=36.1809045226131, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR023170
- InterPro:   IPR005760
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 3.2.2.-

Molecular weight: Translated: 30709; Mature: 30578

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWFDVAERDLPWRRPEATPWHILISEVMLQQTPVSRVEPVWREWVARWPVPSAMAKTSV
CCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AEVLRAWGKLGYPRRAMRLHECATVLARDYDDQVPGDVETLLTLPGVGAYTARAIACFGY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCC
GQRVPVVDTNVRRVIARVVHGVADSAPSARDLRDAEALLPTENGARFSAALMELGALVCT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
ARTPQCPMCPLSSCAWHEAGQPPLDAPARPVQKYAGTDRQVRGRLLDVLRGSSIPVTRAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHH
LDVAWLSDITQRDRALDSLLVDGLVEQTADGRFALAGEGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure 
GWFDVAERDLPWRRPEATPWHILISEVMLQQTPVSRVEPVWREWVARWPVPSAMAKTSV
CCHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
AEVLRAWGKLGYPRRAMRLHECATVLARDYDDQVPGDVETLLTLPGVGAYTARAIACFGY
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHCC
GQRVPVVDTNVRRVIARVVHGVADSAPSARDLRDAEALLPTENGARFSAALMELGALVCT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
ARTPQCPMCPLSSCAWHEAGQPPLDAPARPVQKYAGTDRQVRGRLLDVLRGSSIPVTRAQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHH
LDVAWLSDITQRDRALDSLLVDGLVEQTADGRFALAGEGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: 4Fe-4S Cluster [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Glycosylases; Hydrolysing N-glycosyl compounds [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]