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The map label for this gene is coaX

Identifier: 169627647

GI number: 169627647

Start: 543666

End: 544481

Strand: Direct

Name: coaX

Synonym: MAB_0543

Alternate gene names: 169627647

Gene position: 543666-544481 (Clockwise)

Preceding gene: 169627646

Following gene: 169627648

Centisome position: 10.73

GC content: 66.05

Gene sequence:

>816_bases
GTGCTGTTGGCGATCGACGTACGTAATACCCACACGGTGCTGGGGCTGGTTTCCGGTACGGGCGAGCACGCCAAGGTGGT
TCAGCACTGGCGGATTCGTACCGAAGCGGAGATCACGGCAGACGAACTGGCCCTGACGATCGATGGACTCATCGGCGACG
ACAGCGAGACACTCACCGGGGTCGCGGCGCTTTCCACGGTGCCATCGGTCCTGCACGAAATGCGCGGAATGTTCGATCAG
TACTGGTCGTCGGTTCCGCAGGTGCTGATCGAGCCCGGTGTACGCACCGGGCTCCCGCTGTTGGTGGACAACCCCAAGGA
GGTCGGCGCCGACCGCATCGTCAATTGCCTTGCGGCCCACCACCGATTCGGCTCGGCGTGCATCGTGGTGGATTTCGGTT
CCTCGATCTGTGTGGACGTGGTGTCGGCCAAGGGCGAATTTCTCGGCGGTGCGATCGCCCCGGGCGTGCAGGTGTCCTCC
GATGCCGCCGCCGCCCGTAGCGCCGCGCTGCGCAGAGTCGAGCTGACCAGACCGCGTTCCGTCGTCGGAAAGAACACGGT
CGAGTGCATGCAGTCGGGGGCGGTCTTTGGTTTCGCCGGATTGGTGGACGGGCTCGTGGAACGCGTGCGCCGCGATATCG
ACGGCTTCGGAGCCGCGGGCGTCACGGTGGTGGCCACCGGCCATACCGCGCCGTTGATCCTGCCCGAGACCCACACCGTG
GACCGCTATGAGGAACACCTGACCCTGGATGGTCTGCGGCTGGTGTACGAGCGCAACCGGGCGGACCAGCGCGGCAAGGC
ACGCGCGACCAGGTAG

Upstream 100 bases:

>100_bases
ATTCGGATAACAAGCAGGTAGAACTGGGCGAGCATTCCGATGACCCGGCGTACGTGCCCGAGAACTTCGGCCTGGTGTCA
CCACGCGGTCTGGTGTAACC

Downstream 100 bases:

>100_bases
AGATCCATGCGTCAGATCGGCAGCGCAGTTCAGGTGCGGAGCACTACCGCTAAGCTGCCGAGACGTGACTGATCCTGACG
CGCAGACCAGCTTGCCGGAA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLLAIDVRNTHTVLGLVSGTGEHAKVVQHWRIRTEAEITADELALTIDGLIGDDSETLTGVAALSTVPSVLHEMRGMFDQ
YWSSVPQVLIEPGVRTGLPLLVDNPKEVGADRIVNCLAAHHRFGSACIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSS
DAAAARSAALRRVELTRPRSVVGKNTVECMQSGAVFGFAGLVDGLVERVRRDIDGFGAAGVTVVATGHTAPLILPETHTV
DRYEEHLTLDGLRLVYERNRADQRGKARATR

Sequences:

>Translated_271_residues
MLLAIDVRNTHTVLGLVSGTGEHAKVVQHWRIRTEAEITADELALTIDGLIGDDSETLTGVAALSTVPSVLHEMRGMFDQ
YWSSVPQVLIEPGVRTGLPLLVDNPKEVGADRIVNCLAAHHRFGSACIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSS
DAAAARSAALRRVELTRPRSVVGKNTVECMQSGAVFGFAGLVDGLVERVRRDIDGFGAAGVTVVATGHTAPLILPETHTV
DRYEEHLTLDGLRLVYERNRADQRGKARATR
>Mature_271_residues
MLLAIDVRNTHTVLGLVSGTGEHAKVVQHWRIRTEAEITADELALTIDGLIGDDSETLTGVAALSTVPSVLHEMRGMFDQ
YWSSVPQVLIEPGVRTGLPLLVDNPKEVGADRIVNCLAAHHRFGSACIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSS
DAAAARSAALRRVELTRPRSVVGKNTVECMQSGAVFGFAGLVDGLVERVRRDIDGFGAAGVTVVATGHTAPLILPETHTV
DRYEEHLTLDGLRLVYERNRADQRGKARATR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_MYCA9 (B1MGV8)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001701296.1
- ProteinModelPortal:   B1MGV8
- SMR:   B1MGV8
- EnsemblBacteria:   EBMYCT00000006198
- GeneID:   5963080
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_0543
- GeneTree:   EBGT00050000017438
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   MABS561007:MAB_0543-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28894; Mature: 28894

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: ACT_SITE 111-111 BINDING 134-134 BINDING 186-186

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIDVRNTHTVLGLVSGTGEHAKVVQHWRIRTEAEITADELALTIDGLIGDDSETLTG
CEEEEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHEEEEECCEECCCCHHHHH
VAALSTVPSVLHEMRGMFDQYWSSVPQVLIEPGVRTGLPLLVDNPKEVGADRIVNCLAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHCHHHHHHHHHHH
HRFGSACIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELTRPRS
HCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCHH
VVGKNTVECMQSGAVFGFAGLVDGLVERVRRDIDGFGAAGVTVVATGHTAPLILPETHTV
HHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCH
DRYEEHLTLDGLRLVYERNRADQRGKARATR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLLAIDVRNTHTVLGLVSGTGEHAKVVQHWRIRTEAEITADELALTIDGLIGDDSETLTG
CEEEEEECCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCHHHEEEEECCEECCCCHHHHH
VAALSTVPSVLHEMRGMFDQYWSSVPQVLIEPGVRTGLPLLVDNPKEVGADRIVNCLAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHCHHHHHHHHHHH
HRFGSACIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELTRPRS
HCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHCCCCHH
VVGKNTVECMQSGAVFGFAGLVDGLVERVRRDIDGFGAAGVTVVATGHTAPLILPETHTV
HHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCH
DRYEEHLTLDGLRLVYERNRADQRGKARATR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA