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The map label for this gene is rfbB [C]

Identifier: 169627607

GI number: 169627607

Start: 501424

End: 502356

Strand: Direct

Name: rfbB [C]

Synonym: MAB_0503

Alternate gene names: 169627607

Gene position: 501424-502356 (Clockwise)

Preceding gene: 169627603

Following gene: 169627610

Centisome position: 9.9

GC content: 65.49

Gene sequence:

>933_bases
GTGCGGGCAATGGTTACCGGAGCTGCAGGATTCATCGGGTCGACGCTGGTTGATCGCCTGTTGGCGGACGGGCACGAGGT
AACGGGACTGGATAACCTGGCCACCGGCAAGGTGGCGAACCTGGAGGCCGCCGAGGCGAATGCCAAGTTCACATTCGTCA
AGGACGACATCGTCGAGGCCGACCTGGACGCTGTAGTCGCCGAATACTCCCCTGAGGTGATCTTCCACCTGGCCGCGCAG
ATCGACGTACGTCACTCGGTGGCCGACCCGCAGTTCGATTCCTCCGTCAACGTCGTCGGTACGGTCCGGCTCGCAGAGGC
CGCGCGCAAGGCGGGCGTGCGCAAGATCGTGCACACCTCGTCGGGCGGATCGATCTACGGCACCCCGAAGCAGATTCCGA
CCAGCGAGACAGTTCCCACCGACCCGCACTCGCCATACGCGGCGGGCAAGGTGGCCGGCGAGATCTACCTCAACACCTTC
CGGCACCTGTACGGGCTGGAGTGCTCGCATATCGCCCCTGCCAATGTGTATGGGCCTCGACAGGATCCGCATGGTGAGGC
CGGGGTTGTCGCGATTTTCGCGCAGGCTCTGCTCTCCGGCCGCTCCACCAAGGTGTTCGGCGATGGTGGCAACACTCGCG
ACTACGTGTTTGTCGACGACGTGGTGGAGGCCTTCGTGCGGGCCTCCGGCCCTGACGGTGGCGGGCAGCGTTTCAATGTC
GGCACCGGTGTGGAAACCAGTGACCGGCAACTGCATTCGTTGGTGGCCGCGGCGGCGGGCGCACCGGATGATCCCGAGTT
TCATCCGCCGCGGCTGGGCGACCTGCGTCAGTCGTGCCTGGACGTCGGTCTGGCCAAGAGGGTGCTGGGCTGGGAGCCGC
GGGTGCCGCTAGCGGACGGGATCAGAAGGACCGTTGACTTCTTCCGGAGCTAG

Upstream 100 bases:

>100_bases
GGGGAGTCGGGCTCGCACTGCAGAAGGCATTTGGGCCCGACCCTATCTGTAGGGTGGGGCCGAATGCCGTGAGCTATGCG
AACACAGAGGGAGTCGCCAC

Downstream 100 bases:

>100_bases
CTCCGGAGCAATATCGCCGGACGGGGGCTCGGCACCGCGTAGCGCGACCGCCCTGGTCAGCCGTGAGTAACGCAGCTCGA
GGTCCTTGAAGCGCAGATAC

Product: UDP-glucose 4-epimerase GalE1

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRAMVTGAAGFIGSTLVDRLLADGHEVTGLDNLATGKVANLEAAEANAKFTFVKDDIVEADLDAVVAEYSPEVIFHLAAQ
IDVRHSVADPQFDSSVNVVGTVRLAEAARKAGVRKIVHTSSGGSIYGTPKQIPTSETVPTDPHSPYAAGKVAGEIYLNTF
RHLYGLECSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGRSTKVFGDGGNTRDYVFVDDVVEAFVRASGPDGGGQRFNV
GTGVETSDRQLHSLVAAAAGAPDDPEFHPPRLGDLRQSCLDVGLAKRVLGWEPRVPLADGIRRTVDFFRS

Sequences:

>Translated_310_residues
MRAMVTGAAGFIGSTLVDRLLADGHEVTGLDNLATGKVANLEAAEANAKFTFVKDDIVEADLDAVVAEYSPEVIFHLAAQ
IDVRHSVADPQFDSSVNVVGTVRLAEAARKAGVRKIVHTSSGGSIYGTPKQIPTSETVPTDPHSPYAAGKVAGEIYLNTF
RHLYGLECSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGRSTKVFGDGGNTRDYVFVDDVVEAFVRASGPDGGGQRFNV
GTGVETSDRQLHSLVAAAAGAPDDPEFHPPRLGDLRQSCLDVGLAKRVLGWEPRVPLADGIRRTVDFFRS
>Mature_310_residues
MRAMVTGAAGFIGSTLVDRLLADGHEVTGLDNLATGKVANLEAAEANAKFTFVKDDIVEADLDAVVAEYSPEVIFHLAAQ
IDVRHSVADPQFDSSVNVVGTVRLAEAARKAGVRKIVHTSSGGSIYGTPKQIPTSETVPTDPHSPYAAGKVAGEIYLNTF
RHLYGLECSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGRSTKVFGDGGNTRDYVFVDDVVEAFVRASGPDGGGQRFNV
GTGVETSDRQLHSLVAAAAGAPDDPEFHPPRLGDLRQSCLDVGLAKRVLGWEPRVPLADGIRRTVDFFRS

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=29.6178343949045, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=29.375, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI4504031, Length=338, Percent_Identity=26.6272189349112, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI56237023, Length=336, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI56118217, Length=336, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI189083684, Length=336, Percent_Identity=26.7857142857143, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=29.2537313432836, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788353, Length=341, Percent_Identity=27.5659824046921, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786974, Length=315, Percent_Identity=31.7460317460317, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788366, Length=277, Percent_Identity=29.6028880866426, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=28.1645569620253, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17568069, Length=326, Percent_Identity=26.9938650306748, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17507723, Length=340, Percent_Identity=25, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982038, Length=332, Percent_Identity=29.8192771084337, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982035, Length=333, Percent_Identity=29.4294294294294, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI133901786, Length=340, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI133901788, Length=340, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17539422, Length=340, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI133901790, Length=345, Percent_Identity=24.9275362318841, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17539424, Length=340, Percent_Identity=24.7058823529412, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115532424, Length=324, Percent_Identity=26.5432098765432, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319493, Length=332, Percent_Identity=27.1084337349398, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21356223, Length=324, Percent_Identity=28.3950617283951, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19923002, Length=319, Percent_Identity=29.153605015674, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24158427, Length=348, Percent_Identity=25, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 32829; Mature: 32829

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMVTGAAGFIGSTLVDRLLADGHEVTGLDNLATGKVANLEAAEANAKFTFVKDDIVEA
CCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHH
DLDAVVAEYSPEVIFHLAAQIDVRHSVADPQFDSSVNVVGTVRLAEAARKAGVRKIVHTS
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEEC
SGGSIYGTPKQIPTSETVPTDPHSPYAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPR
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QDPHGEAGVVAIFAQALLSGRSTKVFGDGGNTRDYVFVDDVVEAFVRASGPDGGGQRFNV
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEC
GTGVETSDRQLHSLVAAAAGAPDDPEFHPPRLGDLRQSCLDVGLAKRVLGWEPRVPLADG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IRRTVDFFRS
HHHHHHHHCC
>Mature Secondary Structure
MRAMVTGAAGFIGSTLVDRLLADGHEVTGLDNLATGKVANLEAAEANAKFTFVKDDIVEA
CCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHH
DLDAVVAEYSPEVIFHLAAQIDVRHSVADPQFDSSVNVVGTVRLAEAARKAGVRKIVHTS
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHEEEEC
SGGSIYGTPKQIPTSETVPTDPHSPYAAGKVAGEIYLNTFRHLYGLECSHIAPANVYGPR
CCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QDPHGEAGVVAIFAQALLSGRSTKVFGDGGNTRDYVFVDDVVEAFVRASGPDGGGQRFNV
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEC
GTGVETSDRQLHSLVAAAAGAPDDPEFHPPRLGDLRQSCLDVGLAKRVLGWEPRVPLADG
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IRRTVDFFRS
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]