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The map label for this gene is pbpG [H]

Identifier: 169627512

GI number: 169627512

Start: 408905

End: 411340

Strand: Reverse

Name: pbpG [H]

Synonym: MAB_0408c

Alternate gene names: 169627512

Gene position: 411340-408905 (Counterclockwise)

Preceding gene: 169627514

Following gene: 169627511

Centisome position: 8.12

GC content: 65.35

Gene sequence:

>2436_bases
ATGCCAGAGCGGCTGTCCCCCCAGATACCCCCCTCCGTGACCCTCGCGAAGCTCGCGGGCTGCGGACTTGTCGCGGCGGT
GATCCTGGCCGGGCTGATGTTCCCCTTCGCGGGTGGATTCGGGCTGGCCTCCAATCGCGCATCCGACGTGGTGGCCAATG
GCTCCACTCAGTTGCTTCAGGGTGAGGTGCCCGCCGTCACCACGGTGGAGGACGCCAAGGGCAACAAGATCGCCTATCTG
TACACCCAACGACGCTTCGAGGTGTCGGCCGACGAGATCGCCGACACCATGAAGCTGGCCCTGCTGTCCATCGAGGACAA
GCGCTTCACCTCACATAACGGCGTCGACTGGAAGGGCACGCTCGGCGGACTGGCCGGATACGCCTCCGGGGATGAGGACA
CCCGCGGCGGTTCGACCATCGAGCAGCAGTACGTGAAGAACTACCAGCTGCTGGTGGTGGCCAAGACGGACGCCGAGCGC
AAGGCCGCCATCGAGACCACTCCCGCCCGCAAGTTACGCGAGATCCGGATGGCGCTGCGGCTGGACCAGACCTTCACCAA
GCAGGAAATCCTGACCCGGTACCTGAACCTGGTGTCCTTCGGTAACAACTCGTTCGGCGTGCAGGATGCCGCACAGACCT
ATTTCGGCGTCGACGCGAAGGACCTGAACTGGCAGCAGGCCGCGTTGTTGGCGGGCATGGTGCAGTCCACCTCCGGGCTC
AATCCCTACGTCAACCCCGAACGCGCCCTGGCCCGGCGGAACCTGGTGCTCGACACCATGATCGCCAACTCTCCCGATAA
GAAGGGCGAGCTGCTGGCCGCCAAGGCACAGCCCCTCGGCGTGTTGCCCCAGCCCAACGAGCTGCCGCGCGGCTGCATCG
CCGCTGGTGACCGCGCATTCTTCTGCGATTACGTGCTCGACTACCTGGCCAAGTCCGGCATCAGCAAGGACCAGGTGATG
AAGGGCGGATACCTCATCCGCACCACCCTGGACCCGGATGTGCAGAACTCGGTGAAGCAGGCGGTCTCGCATGTCGCCGA
TCCCGGCCTCAATGGCATCGCCAACGTCATGAGCGTCATCAAGCCGGGACAGACCAGCCACCCCATCTTGGCGATGGCTT
CCAGCCGCACCTACGGTCTGGACGGAAACGCCTTCCAAACCATGCAGCCGCAGCCCTTCTCCCTGGTCGGTGACGGTGCC
GGGTCGATCTTCAAGATCTTCACGGTTGCCGCGGCCATGGATATGGGCATGGGCATCAACACCGTGCTCGACGTGCCGCC
CACCTTCGCGGCCAAGGGCCTGGGCAGCAGCGACGGCTCCAAGGGCTGCCCCAAGGACAACTGGTGCGTCAAGAACGTCG
GCAACTACCGCTCCCCGATGAGCGTCACCGACGCCCTCGCGACCTCCCCGAACACCGCGTTCGCCAAGCTGATTCAGTCG
ATCGGCGTGTCCAAGGCGGTCGATATGGCCGTGAAGTTGGGGATGCGCTCCTATGCGGAGCCGGGTACCGCCAAGCCGTA
TGACCCCGAAGGCGACGAAAGCCTGGCCGAATACATCAAGAAGTACAACCTGGGATCGTTCACCCTCGGCCCGATTCAGA
TCAACCCGCTCGAGCTGTCCAACGTGGCGGCCACCTTGGCCTCCGGCGGCAAGTGGTGCCCGCCGAACCCCATCGACAAG
GTCTTCGATCGTCACGGCAAGGAAGTACCGACGACGGTCGAGGCCTGTGAGCAGGTGGTGCCTACCGGGCTGGCCAACAC
CCTGGCCAACGCCCTGAGCAAGGACGATCAACCCGGCGGTACTGCCGCCGGTTCGGCCGGATCGGTCGGATGGAACCTGC
CGCTGTCCAGCAAGACCGGTACCACCGAGGCGCACCGCTCATCGGCGTTCCTGGGGTACACCAACAACCTGGCCGGGGCG
AGCTACATCTACGACGACTCGACCACCCCGGGCGATCTGTGCTCGTTCCCGCTGCGCAAGTGCGGCGACGGAAATCTGTA
CGGCGGTAATGAGCCCGCGCGCGCCTGGTTCGAGGCGATGAAGCCGATCGCCGACAACTACGGCCCGACGGTGCTGCCGC
CCACCGAACCCCGATACGTCGAAGGCGGCCCGGGATCGAAGGTGCCCAGCATCAACGGTCTGCGCGAGCCCGAGGCGCGT
GACGTTCTCAAGAAGGCGGGCTTCAGGGTGGCCGATCAGGCCAGCTCGGTGAACAGCACGGCACCGTTCAACGAGGTCGT
GGGCACCAGCCCGTCCGGGACCACCATTCCTGGCTCCGTGATCACCATCCTGATGAGCAATGGCATCCCGCCGGCGCCAC
CACCCCTTGTCATTCCGGGTATCCCCGGCGCTCCGCCTGGCGAGATGACCACCACGATCGTCAACATCCCGGGCCTGCCG
CCCATCACCGTGCCGGTGCTGGCGCCACCCCCGTGA

Upstream 100 bases:

>100_bases
CGGTTGTGCCGACAACGTCTTTTCATCGCCCCGAGCGAGCCCCGTGTTACCAATCAACTACCCCGCAGACACCTCTGGGG
ATGCCACGTACCCTGTGCCT

Downstream 100 bases:

>100_bases
TCTAGCTCTCGGTCGTCGCACCAGGCTGCTCATCCGTGACGAGAAATGCGCCACGTTTTGTGCAGGTGATCCGGGGTCCC
TCAGCATTCGGAGTTACCCT

Product: bifunctional membrane-associated penicillin-binding protein PonA2/glycosyl transferase

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 811; Mature: 810

Protein sequence:

>811_residues
MPERLSPQIPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRASDVVANGSTQLLQGEVPAVTTVEDAKGNKIAYL
YTQRRFEVSADEIADTMKLALLSIEDKRFTSHNGVDWKGTLGGLAGYASGDEDTRGGSTIEQQYVKNYQLLVVAKTDAER
KAAIETTPARKLREIRMALRLDQTFTKQEILTRYLNLVSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGL
NPYVNPERALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGDRAFFCDYVLDYLAKSGISKDQVM
KGGYLIRTTLDPDVQNSVKQAVSHVADPGLNGIANVMSVIKPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVGDGA
GSIFKIFTVAAAMDMGMGINTVLDVPPTFAAKGLGSSDGSKGCPKDNWCVKNVGNYRSPMSVTDALATSPNTAFAKLIQS
IGVSKAVDMAVKLGMRSYAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELSNVAATLASGGKWCPPNPIDK
VFDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQPGGTAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGA
SYIYDDSTTPGDLCSFPLRKCGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEPRYVEGGPGSKVPSINGLREPEAR
DVLKKAGFRVADQASSVNSTAPFNEVVGTSPSGTTIPGSVITILMSNGIPPAPPPLVIPGIPGAPPGEMTTTIVNIPGLP
PITVPVLAPPP

Sequences:

>Translated_811_residues
MPERLSPQIPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRASDVVANGSTQLLQGEVPAVTTVEDAKGNKIAYL
YTQRRFEVSADEIADTMKLALLSIEDKRFTSHNGVDWKGTLGGLAGYASGDEDTRGGSTIEQQYVKNYQLLVVAKTDAER
KAAIETTPARKLREIRMALRLDQTFTKQEILTRYLNLVSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGL
NPYVNPERALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGDRAFFCDYVLDYLAKSGISKDQVM
KGGYLIRTTLDPDVQNSVKQAVSHVADPGLNGIANVMSVIKPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVGDGA
GSIFKIFTVAAAMDMGMGINTVLDVPPTFAAKGLGSSDGSKGCPKDNWCVKNVGNYRSPMSVTDALATSPNTAFAKLIQS
IGVSKAVDMAVKLGMRSYAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELSNVAATLASGGKWCPPNPIDK
VFDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQPGGTAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGA
SYIYDDSTTPGDLCSFPLRKCGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEPRYVEGGPGSKVPSINGLREPEAR
DVLKKAGFRVADQASSVNSTAPFNEVVGTSPSGTTIPGSVITILMSNGIPPAPPPLVIPGIPGAPPGEMTTTIVNIPGLP
PITVPVLAPPP
>Mature_810_residues
PERLSPQIPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRASDVVANGSTQLLQGEVPAVTTVEDAKGNKIAYLY
TQRRFEVSADEIADTMKLALLSIEDKRFTSHNGVDWKGTLGGLAGYASGDEDTRGGSTIEQQYVKNYQLLVVAKTDAERK
AAIETTPARKLREIRMALRLDQTFTKQEILTRYLNLVSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGLN
PYVNPERALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGDRAFFCDYVLDYLAKSGISKDQVMK
GGYLIRTTLDPDVQNSVKQAVSHVADPGLNGIANVMSVIKPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVGDGAG
SIFKIFTVAAAMDMGMGINTVLDVPPTFAAKGLGSSDGSKGCPKDNWCVKNVGNYRSPMSVTDALATSPNTAFAKLIQSI
GVSKAVDMAVKLGMRSYAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELSNVAATLASGGKWCPPNPIDKV
FDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQPGGTAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGAS
YIYDDSTTPGDLCSFPLRKCGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEPRYVEGGPGSKVPSINGLREPEARD
VLKKAGFRVADQASSVNSTAPFNEVVGTSPSGTTIPGSVITILMSNGIPPAPPPLVIPGIPGAPPGEMTTTIVNIPGLPP
ITVPVLAPPP

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI87082258, Length=322, Percent_Identity=29.5031055900621, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1786343, Length=583, Percent_Identity=25.557461406518, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789601, Length=176, Percent_Identity=35.2272727272727, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1788867, Length=200, Percent_Identity=29.5, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.-; 3.4.-.- [C]

Molecular weight: Translated: 85281; Mature: 85150

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERLSPQIPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRASDVVANGSTQLLQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEECCCCCEEE
GEVPAVTTVEDAKGNKIAYLYTQRRFEVSADEIADTMKLALLSIEDKRFTSHNGVDWKGT
CCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCC
LGGLAGYASGDEDTRGGSTIEQQYVKNYQLLVVAKTDAERKAAIETTPARKLREIRMALR
CCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHH
LDQTFTKQEILTRYLNLVSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
NPYVNPERALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGDRAF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHCCCCHH
FCDYVLDYLAKSGISKDQVMKGGYLIRTTLDPDVQNSVKQAVSHVADPGLNGIANVMSVI
HHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVGDGAGSIFKIFTVAAAMDMGMGIN
CCCCCCCCEEEEECCCEECCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCC
TVLDVPPTFAAKGLGSSDGSKGCPKDNWCVKNVGNYRSPMSVTDALATSPNTAFAKLIQS
CEECCCCHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHH
IGVSKAVDMAVKLGMRSYAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELS
HCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCEEECCEEHH
NVAATLASGGKWCPPNPIDKVFDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQPGG
HHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
TAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGASYIYDDSTTPGDLCSFPLRK
CCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEECCCCCCCEEEECCCCCCHHHHHCHHHH
CGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEPRYVEGGPGSKVPSINGLREPEAR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
DVLKKAGFRVADQASSVNSTAPFNEVVGTSPSGTTIPGSVITILMSNGIPPAPPPLVIPG
HHHHHCCCEEHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECC
IPGAPPGEMTTTIVNIPGLPPITVPVLAPPP
CCCCCCCCCEEEEEECCCCCCCEEECCCCCC
>Mature Secondary Structure 
PERLSPQIPPSVTLAKLAGCGLVAAVILAGLMFPFAGGFGLASNRASDVVANGSTQLLQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEECCCCCEEE
GEVPAVTTVEDAKGNKIAYLYTQRRFEVSADEIADTMKLALLSIEDKRFTSHNGVDWKGT
CCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCC
LGGLAGYASGDEDTRGGSTIEQQYVKNYQLLVVAKTDAERKAAIETTPARKLREIRMALR
CCCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEEEECCCCHHHHCCCCHHHHHHHHHHHHH
LDQTFTKQEILTRYLNLVSFGNNSFGVQDAAQTYFGVDAKDLNWQQAALLAGMVQSTSGL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
NPYVNPERALARRNLVLDTMIANSPDKKGELLAAKAQPLGVLPQPNELPRGCIAAGDRAF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHCCCCHH
FCDYVLDYLAKSGISKDQVMKGGYLIRTTLDPDVQNSVKQAVSHVADPGLNGIANVMSVI
HHHHHHHHHHHCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KPGQTSHPILAMASSRTYGLDGNAFQTMQPQPFSLVGDGAGSIFKIFTVAAAMDMGMGIN
CCCCCCCCEEEEECCCEECCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCC
TVLDVPPTFAAKGLGSSDGSKGCPKDNWCVKNVGNYRSPMSVTDALATSPNTAFAKLIQS
CEECCCCHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHH
IGVSKAVDMAVKLGMRSYAEPGTAKPYDPEGDESLAEYIKKYNLGSFTLGPIQINPLELS
HCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCEEECCEEHH
NVAATLASGGKWCPPNPIDKVFDRHGKEVPTTVEACEQVVPTGLANTLANALSKDDQPGG
HHHHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
TAAGSAGSVGWNLPLSSKTGTTEAHRSSAFLGYTNNLAGASYIYDDSTTPGDLCSFPLRK
CCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEECCCCCCCEEEECCCCCCHHHHHCHHHH
CGDGNLYGGNEPARAWFEAMKPIADNYGPTVLPPTEPRYVEGGPGSKVPSINGLREPEAR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCHHH
DVLKKAGFRVADQASSVNSTAPFNEVVGTSPSGTTIPGSVITILMSNGIPPAPPPLVIPG
HHHHHCCCEEHHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECC
IPGAPPGEMTTTIVNIPGLPPITVPVLAPPP
CCCCCCCCCEEEEEECCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]