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The map label for this gene is recD [H]

Identifier: 169627502

GI number: 169627502

Start: 393871

End: 395529

Strand: Reverse

Name: recD [H]

Synonym: MAB_0398c

Alternate gene names: 169627502

Gene position: 395529-393871 (Counterclockwise)

Preceding gene: 169627503

Following gene: 169627501

Centisome position: 7.81

GC content: 68.23

Gene sequence:

>1659_bases
ATGAGCTTGGTGGAGGCGTTCGGCGAGATCCTCGAACCCGCGGATGTGCATGTGGCGCAGCGGCTGACGGCGTTGGCATC
CGAGACCGATGAGTCGGTGGAGCTGGCAATCGCGCTGGCGGTGCGGGCACTGCGCGGCGGGTCGGTGTGTGTGGATTTGC
GCGCGGTGGCGGCGCAGGTGGATATGCCCTCGCTGCCGTGGCCCGCTGCCGATGACTGGCTGGCGGCGGTGCGGGCCAGC
CCCTTGGCGGGTGAGCCGCCCGTGCTGCGGCTTTTCGGCGACCTGCTGTACCTCGATCGGTACTGGCGCGAGGAACAACA
GGTGTGCACAGATGTGCAAGCGTTGATGGCCGCCGCCCAACCACGCACCGAAGTGCCCACCTATGAGCGACTTTTCCCGC
AGGGATTCGAAGAGCAGCGCGCCGCTGCCGATATTGCGCTGTCACAGGGCCTGACCGTGCTGACGGGCGGGCCGGGCACG
GGCAAGACCACCACGGTGGCACGGCTGTTGGCGCTGCTGGCCGACCAGGCATCATCGGCGAGCGCCGCGCCGTTGCGTAT
CGCGCTGGCAGCACCGACAGGCAAGGCCGCGGCCCGGCTGCAGGAAGCGGTGCAGCTGGAGGTCAACCAGCTGGATGCCG
TCGACCGGTCGCGGTTGGCCGGGTTGCAGGCGACCACGCTGCATCGTCTGTTGGGATCGCGCCCCGACACGTCGTCCCGG
TTCAAACATGATCGCGGAAACCGGTTGCCGCACGATGTGATTGTGGTGGACGAGACGTCGATGGTGTCGCTGACCATGAT
GGCGCGACTGTTGGAGGCGGTGCGCCCGCAGGCCCGACTGCTGCTGGTGGGTGATCCTGATCAGCTGGCCTCGGTGGAGG
CGGGCGCGGTGCTGGCCGATCTGGTCGAGGGCCTGGAGTCCGAACGGGTGGCGGCACTGCGCACGTCGCACCGTTTCGGT
GCGGCGATTGGCGCGTTGGCGGCGGCGGTGCGTGACGGAGACGCGGATCGCGCGCTAGAGGTGCTGGCATCTGGCGATCC
GCATGTGGAGTGGTCGACGGATTCAGAGGGGTTACGCGATGTGCTTGTCCCCCAGGCACTTGCATTGCGTGCGGCAAGCC
TGTCCGGTGATGCCACAGCGGCGCTGGCCGTGCTCGACGAGCACCGGATGCTATGCGCGCATCGCCACGGGCCGTTCGGG
GTGACGCACTGGAACCGCCAGGTGGAGCGGTGGATCACCGAGGAGACGGGCGAGCCGCACTGGGCACCCTGGTATGCGGG
AAGACCGATCCTGGTCACCGCCAATGACTATGGCTTGCGTCTGTACAACGGTGACACCGGCGTGACGGTGGCCGGACCTG
ACGGGCTGCGCGCGGTGATCGGCGCAGCATCGTTTGCGACCAGCCGTCTGGTTGAGGTGGAGACCATGCACGCCATGACC
ATTCACAAGTCCCAGGGCAGCCAGGCGAATGAAGTGACGGTGCTGCTGCCGTCTGAAGATTCCCGGCTGCTGACACGCGA
GCTGTTCTACACGGCGGTCACGCGCGCCAAGCAGCGCGTGCGGGTGGTGGGCTCGGAGGCCGAGGTGCGGGCCGCGATCC
AGCGGCAGGCGGTGCGGGCGTCGGGGTTGGGGCGGCGACTGCGCCACAGCCCGAACTGA

Upstream 100 bases:

>100_bases
TGTGTGGCGCGACTACCCCGGTGGTAGAGGGGCATCCGGCCGGGGTGTTCAGCTGGCAGCCGCCCTCGGCGCTGGTGGTC
GCGCTGTCGGAGCTGCTGTC

Downstream 100 bases:

>100_bases
TGTCGACCAATCGATGCATTTGCGAATAGAACAATCACTCATCGAGGCGCGCGTTAGTAGTCCATCCCAACACACATACG
ATCTCGCCCATGGCAGACTC

Product: exodeoxyribonuclease V, alpha subunit (RecD)

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MSLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMPSLPWPAADDWLAAVRAS
PLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQPRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGT
GKTTTVARLLALLADQASSASAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR
FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLADLVEGLESERVAALRTSHRFG
AAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRDVLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFG
VTHWNRQVERWITEETGEPHWAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT
IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN

Sequences:

>Translated_552_residues
MSLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMPSLPWPAADDWLAAVRAS
PLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQPRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGT
GKTTTVARLLALLADQASSASAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR
FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLADLVEGLESERVAALRTSHRFG
AAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRDVLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFG
VTHWNRQVERWITEETGEPHWAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT
IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN
>Mature_551_residues
SLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQVDMPSLPWPAADDWLAAVRASP
LAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQPRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGTG
KTTTVARLLALLADQASSASAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSRF
KHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLADLVEGLESERVAALRTSHRFGA
AIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRDVLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGV
THWNRQVERWITEETGEPHWAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMTI
HKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRASGLGRRLRHSPN

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=598, Percent_Identity=36.6220735785953, Blast_Score=260, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 59221; Mature: 59090

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQV
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHC
DMPSLPWPAADDWLAAVRASPLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQ
CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGTGKTTTVARLLALLADQASSA
CCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
SAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLAD
HCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHH
LVEGLESERVAALRTSHRFGAAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRD
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCHHH
VLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGVTHWNRQVERWITEETGEPH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
WAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT
CCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEE
IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRA
EECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SGLGRRLRHSPN
HHHHHHHCCCCC
>Mature Secondary Structure 
SLVEAFGEILEPADVHVAQRLTALASETDESVELAIALAVRALRGGSVCVDLRAVAAQV
CHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHC
DMPSLPWPAADDWLAAVRASPLAGEPPVLRLFGDLLYLDRYWREEQQVCTDVQALMAAAQ
CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRTEVPTYERLFPQGFEEQRAAADIALSQGLTVLTGGPGTGKTTTVARLLALLADQASSA
CCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
SAAPLRIALAAPTGKAAARLQEAVQLEVNQLDAVDRSRLAGLQATTLHRLLGSRPDTSSR
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHH
FKHDRGNRLPHDVIVVDETSMVSLTMMARLLEAVRPQARLLLVGDPDQLASVEAGAVLAD
HCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHH
LVEGLESERVAALRTSHRFGAAIGALAAAVRDGDADRALEVLASGDPHVEWSTDSEGLRD
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEECCCCCCHHH
VLVPQALALRAASLSGDATAALAVLDEHRMLCAHRHGPFGVTHWNRQVERWITEETGEPH
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCC
WAPWYAGRPILVTANDYGLRLYNGDTGVTVAGPDGLRAVIGAASFATSRLVEVETMHAMT
CCCCCCCCEEEEEECCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEE
IHKSQGSQANEVTVLLPSEDSRLLTRELFYTAVTRAKQRVRVVGSEAEVRAAIQRQAVRA
EECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SGLGRRLRHSPN
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]