Click here to switch to the map view.

The map label for this gene is ligC [H]

Identifier: 169627384

GI number: 169627384

Start: 278241

End: 279272

Strand: Reverse

Name: ligC [H]

Synonym: MAB_0279c

Alternate gene names: 169627384

Gene position: 279272-278241 (Counterclockwise)

Preceding gene: 169627388

Following gene: 169627383

Centisome position: 5.51

GC content: 62.79

Gene sequence:

>1032_bases
ATGCTTGCCAAACCTGTCGCAAAAATCCCTGACGGCGCCTCCTACGAACCCAAGTGGGATGGATTCAGGTCGATCGTCTT
TCGCGACGGCGACGAGGTGGAGCTGGGTAGCCGCAATGAGAAGCCACTGACCCGGTACTTCCCCGAGTTGGTAGCGGCGG
TGCTCGCCGAACTACCGCCACGGTGTGTCGTCGACGGTGAGATCGTGATCGCCACCGAGGCGGGTCTGGATTTCGAGGCG
CTGCAACAACGGATCCACCCGGCGGATTCGCGGGTACGGCTGTTGGCCGAGCAGACACCCTCCTCCTTCATCGCATTCGA
CCTGCTCGCCTTGGGCGACGAGGACTACACCGGGCGGCCCTTCAGCGAGCGCCGTGCCGCGCTGACGGAAGCGCTCTCGA
GTGCCGGGACCTCGATACATCTGACCCCCGCCACCACAGATCAGGCACTGGCGCAGCGCTGGTTCGAGGAATTCGAGGGC
GCCGGTACCGACGGTCTCATCGCCAAACCGTTGGCCATCGCCTACCAACCCGACAAACGAGTGATGTTCAAGATCAAGCC
GGAGCGAACCGCCGATTGCGTGGTCGCGGGCTACCGAGTGCACAAATCGGGTGACGATGCCATCGGCTCGCTGCTGCTGG
GCCTGTACCAGGAGGACGGCATATTGGCGTCGGTCGGTGTGATCGGCGCGTTCCCCATGGCCGAACGCAAGCGCCTATTC
CAAGAACTGCAACCGTTGATCATCCCGCTCGAAAATCACCCGTGGAACTGGGCCGCACACGAAGCCGGCGAGCGCACTCC
GCAGAAGAACGCCGGCTCCCGCTGGAACGCGGGCAAGGATCTTTCGTTTGTCCCGCTGCGTCCCGAGCGAGTGGTGGAGG
TTCGCTACGACCACATGGAGGGTGTGCGGTTCCGTCATACCGCGCAGTTCAACCGCTGGCGCCCGGATCGCGACCCGCGA
TCCTGCACCTACGAGCAGCTAGAACAACCAATTACATTCAGCCTCAACGATATCGTTCCAGGTCTGGTGTGA

Upstream 100 bases:

>100_bases
GCCGGACGGCGATACCGTCGACATCCAGTTCCTCGGCGGGCGTGGGCATTACCGTCATCATATGGGAATGGACCTGCCCG
TCATGCCTCCAATCGCGCCA

Downstream 100 bases:

>100_bases
CCGGGGCAGGACGTTTCGCGCCGAGCCCGTCGGGCGATCTGCACATAGGAAATCTGCGGACGGCGCTGTTGGCGTGGCTG
CTCGCGCACTCGACGGGCCG

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLAKPVAKIPDGASYEPKWDGFRSIVFRDGDEVELGSRNEKPLTRYFPELVAAVLAELPPRCVVDGEIVIATEAGLDFEA
LQQRIHPADSRVRLLAEQTPSSFIAFDLLALGDEDYTGRPFSERRAALTEALSSAGTSIHLTPATTDQALAQRWFEEFEG
AGTDGLIAKPLAIAYQPDKRVMFKIKPERTADCVVAGYRVHKSGDDAIGSLLLGLYQEDGILASVGVIGAFPMAERKRLF
QELQPLIIPLENHPWNWAAHEAGERTPQKNAGSRWNAGKDLSFVPLRPERVVEVRYDHMEGVRFRHTAQFNRWRPDRDPR
SCTYEQLEQPITFSLNDIVPGLV

Sequences:

>Translated_343_residues
MLAKPVAKIPDGASYEPKWDGFRSIVFRDGDEVELGSRNEKPLTRYFPELVAAVLAELPPRCVVDGEIVIATEAGLDFEA
LQQRIHPADSRVRLLAEQTPSSFIAFDLLALGDEDYTGRPFSERRAALTEALSSAGTSIHLTPATTDQALAQRWFEEFEG
AGTDGLIAKPLAIAYQPDKRVMFKIKPERTADCVVAGYRVHKSGDDAIGSLLLGLYQEDGILASVGVIGAFPMAERKRLF
QELQPLIIPLENHPWNWAAHEAGERTPQKNAGSRWNAGKDLSFVPLRPERVVEVRYDHMEGVRFRHTAQFNRWRPDRDPR
SCTYEQLEQPITFSLNDIVPGLV
>Mature_343_residues
MLAKPVAKIPDGASYEPKWDGFRSIVFRDGDEVELGSRNEKPLTRYFPELVAAVLAELPPRCVVDGEIVIATEAGLDFEA
LQQRIHPADSRVRLLAEQTPSSFIAFDLLALGDEDYTGRPFSERRAALTEALSSAGTSIHLTPATTDQALAQRWFEEFEG
AGTDGLIAKPLAIAYQPDKRVMFKIKPERTADCVVAGYRVHKSGDDAIGSLLLGLYQEDGILASVGVIGAFPMAERKRLF
QELQPLIIPLENHPWNWAAHEAGERTPQKNAGSRWNAGKDLSFVPLRPERVVEVRYDHMEGVRFRHTAQFNRWRPDRDPR
SCTYEQLEQPITFSLNDIVPGLV

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 38305; Mature: 38305

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKPVAKIPDGASYEPKWDGFRSIVFRDGDEVELGSRNEKPLTRYFPELVAAVLAELPP
CCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCC
RCVVDGEIVIATEAGLDFEALQQRIHPADSRVRLLAEQTPSSFIAFDLLALGDEDYTGRP
CEEECCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC
FSERRAALTEALSSAGTSIHLTPATTDQALAQRWFEEFEGAGTDGLIAKPLAIAYQPDKR
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCEECCEEEEECCCCE
VMFKIKPERTADCVVAGYRVHKSGDDAIGSLLLGLYQEDGILASVGVIGAFPMAERKRLF
EEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCHHHHHHHH
QELQPLIIPLENHPWNWAAHEAGERTPQKNAGSRWNAGKDLSFVPLRPERVVEVRYDHME
HHCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCHHEEEEEHHHHC
GVRFRHTAQFNRWRPDRDPRSCTYEQLEQPITFSLNDIVPGLV
CCEEEEHHHHHCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCC
>Mature Secondary Structure
MLAKPVAKIPDGASYEPKWDGFRSIVFRDGDEVELGSRNEKPLTRYFPELVAAVLAELPP
CCCCCCCCCCCCCCCCCCCCCHHEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCC
RCVVDGEIVIATEAGLDFEALQQRIHPADSRVRLLAEQTPSSFIAFDLLALGDEDYTGRP
CEEECCCEEEEEECCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCC
FSERRAALTEALSSAGTSIHLTPATTDQALAQRWFEEFEGAGTDGLIAKPLAIAYQPDKR
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCEECCEEEEECCCCE
VMFKIKPERTADCVVAGYRVHKSGDDAIGSLLLGLYQEDGILASVGVIGAFPMAERKRLF
EEEEECCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCHHHHHHHH
QELQPLIIPLENHPWNWAAHEAGERTPQKNAGSRWNAGKDLSFVPLRPERVVEVRYDHME
HHCCCEEEEECCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCHHEEEEEHHHHC
GVRFRHTAQFNRWRPDRDPRSCTYEQLEQPITFSLNDIVPGLV
CCEEEEHHHHHCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA