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The map label for this gene is csdA [C]

Identifier: 169627311

GI number: 169627311

Start: 216223

End: 217419

Strand: Direct

Name: csdA [C]

Synonym: MAB_0206

Alternate gene names: 169627311

Gene position: 216223-217419 (Clockwise)

Preceding gene: 169627304

Following gene: 169627313

Centisome position: 4.27

GC content: 66.75

Gene sequence:

>1197_bases
ATGGCATATGACGTCGCCCGGGTGCGTGGTTTGCACCCGACCCTCGGCGACGGGTGGGTACATTTCGATACCCAGGCCGG
GATGTTGATTCCCGATGCGGTTGCTACGACTGTATCCACAGCTTTCCGGGGATCCTTTTCCGACACGCGGGGCCCGCACC
CCAGCGCGCGCCGCAGCGCTGCCGTTCTGGAGGCCGCCCGACACGCCGCCGCCGACCTGGTGGGCGCTGACGCGCGCGGC
GTGGTGCTGGGCAGCGATCGTGCGATTCTGCTCAACTCCCTGGCCGAGGGATCGTCGTCCAAGGCGGGACTCGGCTATGA
GCTGGTGGTATCCAGACTCGACGAAGAGGCCAACGTGCAGCCATGGCTGCGGTCCGCCAACCGGTACGGCGCCAAGGTCA
AGTGGGCCGAGGTCGACATCGAGTCGGGTGATCTGCCGTCCTGGCAGTGGGAGTCTTTGATTACCAAGCCGACTCGTCTG
GTGGCGGTGACGGCAGCGTCGTCGACGCTGGGCACGGTGCCGGACCTGCAGCAGGCCACCAAGCTCGCACACGCGGTCGG
TGGCCTGGTGGTGATGGACTGCTCAAGCCTGGTGCCGTATCGGGCCTTCGATATCGAAGACCTGGACGCCGACGTGATCG
CCTTCAACGCAACCGCCTGGGGCGGACCGCCGGTGGGCGCGTTGGTCTTCCGCGACCCCGCTCTACTGGATTCGATCAGC
TCCATCTCGCTCAACCCGCTGGCGAGCGGACCCGCGCGGTTGGAGCTGGGTGGACACCAGTTCGCGATGCTGGCCGGACT
GGTGGCCAGTGTGGAATACCTGGCCGGTTTAGACGAGTCGGCGTCCGGCACCCGGCGTGAGCGGCTGCTGACGTCTCTGA
ACTCTGCGGGCGCATATCTGGACTGGCTGTTCCGGTACCTGGTGAGCGCGCTGAGGACTCTGCCACGGGTCATGGTCATC
GGTGCCCCCGAGGACCGGATTCCGGCGCTCAGCTTCACCGTGATCGGGGTTCCGGCGGATCGGGTGGTGCAGCGGTTGGC
CGACAACGGGGTCTGCGCGATCGCCAACACCAGCTCCCGGGTGCTCGATGCCATCGGCGTAAACGAGATCGGCGGCGCGA
TAACAGTTGGTCTGGGCCACTATTCGACGGCCGCCGAGGTCGATCAACTGGTGCGCGCGGTCGCCTCGCTGGGCTGA

Upstream 100 bases:

>100_bases
ATGACTACACGAGACGGCGCCGCTAACCGTCGTCCGTCGGGGCATGGTGCAACGACGGGTTCAGCGCCGTGACCTGTGGT
GAGCATCTAAGGTGTCTGGC

Downstream 100 bases:

>100_bases
TCCACCCCCTGCCGGGTCAGCGGGTCAGCAGCACCTTGCCCACCACCGCGCCGTTCTCCAGCAGGCGATGTGCCTCGGCG
GCCTGGCTCAGCGGGATCTC

Product: aminotransferase/cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTRGPHPSARRSAAVLEAARHAAADLVGADARG
VVLGSDRAILLNSLAEGSSSKAGLGYELVVSRLDEEANVQPWLRSANRYGAKVKWAEVDIESGDLPSWQWESLITKPTRL
VAVTAASSTLGTVPDLQQATKLAHAVGGLVVMDCSSLVPYRAFDIEDLDADVIAFNATAWGGPPVGALVFRDPALLDSIS
SISLNPLASGPARLELGGHQFAMLAGLVASVEYLAGLDESASGTRRERLLTSLNSAGAYLDWLFRYLVSALRTLPRVMVI
GAPEDRIPALSFTVIGVPADRVVQRLADNGVCAIANTSSRVLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG

Sequences:

>Translated_398_residues
MAYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTRGPHPSARRSAAVLEAARHAAADLVGADARG
VVLGSDRAILLNSLAEGSSSKAGLGYELVVSRLDEEANVQPWLRSANRYGAKVKWAEVDIESGDLPSWQWESLITKPTRL
VAVTAASSTLGTVPDLQQATKLAHAVGGLVVMDCSSLVPYRAFDIEDLDADVIAFNATAWGGPPVGALVFRDPALLDSIS
SISLNPLASGPARLELGGHQFAMLAGLVASVEYLAGLDESASGTRRERLLTSLNSAGAYLDWLFRYLVSALRTLPRVMVI
GAPEDRIPALSFTVIGVPADRVVQRLADNGVCAIANTSSRVLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG
>Mature_397_residues
AYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTRGPHPSARRSAAVLEAARHAAADLVGADARGV
VLGSDRAILLNSLAEGSSSKAGLGYELVVSRLDEEANVQPWLRSANRYGAKVKWAEVDIESGDLPSWQWESLITKPTRLV
AVTAASSTLGTVPDLQQATKLAHAVGGLVVMDCSSLVPYRAFDIEDLDADVIAFNATAWGGPPVGALVFRDPALLDSISS
ISLNPLASGPARLELGGHQFAMLAGLVASVEYLAGLDESASGTRRERLLTSLNSAGAYLDWLFRYLVSALRTLPRVMVIG
APEDRIPALSFTVIGVPADRVVQRLADNGVCAIANTSSRVLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789175, Length=410, Percent_Identity=27.3170731707317, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787970, Length=413, Percent_Identity=24.9394673123487, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994898, Length=343, Percent_Identity=24.4897959183673, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319831, Length=396, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41718; Mature: 41586

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTRGPHPSARRSA
CCCCCHHHCCCCCCCCCCEEEEECCCCEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
AVLEAARHAAADLVGADARGVVLGSDRAILLNSLAEGSSSKAGLGYELVVSRLDEEANVQ
HHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
PWLRSANRYGAKVKWAEVDIESGDLPSWQWESLITKPTRLVAVTAASSTLGTVPDLQQAT
HHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
KLAHAVGGLVVMDCSSLVPYRAFDIEDLDADVIAFNATAWGGPPVGALVFRDPALLDSIS
HHHHHHCCEEEEEHHHCCCEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHH
SISLNPLASGPARLELGGHQFAMLAGLVASVEYLAGLDESASGTRRERLLTSLNSAGAYL
HCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
DWLFRYLVSALRTLPRVMVIGAPEDRIPALSFTVIGVPADRVVQRLADNGVCAIANTSSR
HHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEECCHHHHHHHHHCCCEEEEECCCHH
VLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG
HHHHCCCHHCCCEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYDVARVRGLHPTLGDGWVHFDTQAGMLIPDAVATTVSTAFRGSFSDTRGPHPSARRSA
CCCCHHHCCCCCCCCCCEEEEECCCCEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
AVLEAARHAAADLVGADARGVVLGSDRAILLNSLAEGSSSKAGLGYELVVSRLDEEANVQ
HHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
PWLRSANRYGAKVKWAEVDIESGDLPSWQWESLITKPTRLVAVTAASSTLGTVPDLQQAT
HHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHH
KLAHAVGGLVVMDCSSLVPYRAFDIEDLDADVIAFNATAWGGPPVGALVFRDPALLDSIS
HHHHHHCCEEEEEHHHCCCEEECCCCCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHH
SISLNPLASGPARLELGGHQFAMLAGLVASVEYLAGLDESASGTRRERLLTSLNSAGAYL
HCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHH
DWLFRYLVSALRTLPRVMVIGAPEDRIPALSFTVIGVPADRVVQRLADNGVCAIANTSSR
HHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEEEECCHHHHHHHHHCCCEEEEECCCHH
VLDAIGVNEIGGAITVGLGHYSTAAEVDQLVRAVASLG
HHHHCCCHHCCCEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA