Click here to switch to the map view.

The map label for this gene is yicL

Identifier: 16767049

GI number: 16767049

Start: 3965692

End: 3966594

Strand: Direct

Name: yicL

Synonym: STM3765

Alternate gene names: 16767049

Gene position: 3965692-3966594 (Clockwise)

Preceding gene: 16767045

Following gene: 16767058

Centisome position: 81.64

GC content: 53.49

Gene sequence:

>903_bases
ATGGGTTCCACCAGAAAAGGGATGCTAAACGTCCTGATTGCCGCCGTATTGTGGGGGAGTTCAGGCGTTTGCGCGCAGTA
CATCATGGAGCAAAGCCGTATGTCGTCACAGTTCCTGACGATGATACGTTTGTTATTCGCCGGGCTGATACTGGTGACCT
TCTCCTTTATGCACGGCGATAAGATATTTTCAATTCTTAAAAACCGCAAAGATGCCCTGAGTCTGCTGATTTTCTCCGTG
GTGGGCGCGCTCACCGTTCAGCTAACCTTCCTGCTCACGATTGAAAAATCCAATGCCGCCACCGCGACAGTGCTGCAATT
TTTATCGCCGACCATTATTGTAGCGTGGTTTGCATTAGCGCGAAGAACACGACCAGGCATTCTGGTCTTAACCGCCATTC
TTACATCGCTTATCGGCACCTTTTTACTGGTGACTCACGGCAATCCAACATCGCTGTCGATCTCTTCAGCCGCGCTGTTC
TGGGGTATCGCCTCCGCATTTGCCGCCGCCTTTTATACGACCTGGCCTTCCAGGCTAATCGCCCAATACGGCACACTGCC
AGTGGTCGGCTGGAGTATGTCCTTTGGCGGCCTTATTCTGCTGCCCTTCTACGCTAAAGAAGGAACGCACTTTGCGGTGA
GCGGCAGCCTGATTCTGGCCTTTTTCTACCTGGTGGTGATCGGTACATCGCTGACGTTCAGCCTGTATTTGAAAGGCGCG
CAACTGATTGGTGGCCCCAAAGCCAGCATTTTAAGCTGCGCGGAACCGTTAAGCAGCGCCCTGCTGTCGCTACTGCTGTT
GGGGATTAGTTTTACCTTGCCGGACTGGCTGGGCACGCTGCTCATTCTCTCGTCAGTGATTCTGATCTCCCTCGATTCCC
GTCGACGCGCGCGGGCCGCTTAA

Upstream 100 bases:

>100_bases
TCGTCTGAAATCATTAAACAATAAATTCCTGCTTAATACCGGCGATAGCTCTGTTATGATGCCTGCACGTAAAAAAATAA
AACAACATGACGAGGAAAAA

Downstream 100 bases:

>100_bases
CGCCGTTGATAATCACGATGACCGGGCGGAAGAGGGAAAAGTTTAATGGCGCTTTGCCTTAATCTCTTCGTCAGAAAGCC
CGGTAATCATCAGCACCATC

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRLLFAGLILVTFSFMHGDKIFSILKNRKDALSLLIFSV
VGALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFALARRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSAALF
WGIASAFAAAFYTTWPSRLIAQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLILAFFYLVVIGTSLTFSLYLKGA
QLIGGPKASILSCAEPLSSALLSLLLLGISFTLPDWLGTLLILSSVILISLDSRRRARAA

Sequences:

>Translated_300_residues
MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRLLFAGLILVTFSFMHGDKIFSILKNRKDALSLLIFSV
VGALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFALARRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSAALF
WGIASAFAAAFYTTWPSRLIAQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLILAFFYLVVIGTSLTFSLYLKGA
QLIGGPKASILSCAEPLSSALLSLLLLGISFTLPDWLGTLLILSSVILISLDSRRRARAA
>Mature_299_residues
GSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRLLFAGLILVTFSFMHGDKIFSILKNRKDALSLLIFSVV
GALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFALARRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSAALFW
GIASAFAAAFYTTWPSRLIAQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLILAFFYLVVIGTSLTFSLYLKGAQ
LIGGPKASILSCAEPLSSALLSLLLLGISFTLPDWLGTLLILSSVILISLDSRRRARAA

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains

Homologues:

Organism=Escherichia coli, GI1790092, Length=298, Percent_Identity=89.9328859060403, Blast_Score=508, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YICL_SALTY (O33787)

Other databases:

- EMBL:   AE006468
- EMBL:   AJ000509
- RefSeq:   NP_462664.1
- GeneID:   1255289
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM3765
- NMPDR:   fig|99287.1.peg.3639
- HOGENOM:   HBG702365
- OMA:   VSTEWLV
- ProtClustDB:   CLSK880756
- BioCyc:   STYP99287:STM3765-MONOMER
- GO:   GO:0006810
- InterPro:   IPR004779
- InterPro:   IPR000620
- TIGRFAMs:   TIGR00950

Pfam domain/function: PF00892 DUF6

EC number: NA

Molecular weight: Translated: 32212; Mature: 32081

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11e36c10)-; HASH(0x12988020)-; HASH(0xf3c32e0)-; HASH(0x40981030)-; HASH(0x12e45ff8)-; HASH(0x12550820)-; HASH(0x12966074)-; HASH(0x128f8bb4)-; HASH(0x12e48d30)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRLLFAGLILVTFSFMHGD
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIFSILKNRKDALSLLIFSVVGALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFALA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSAALFWGIASAFAAAFYTTWPSRLI
HCCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLILAFFYLVVIGTSLTFSLYLKGA
HHHCCCCEEECCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCH
QLIGGPKASILSCAEPLSSALLSLLLLGISFTLPDWLGTLLILSSVILISLDSRRRARAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHCCCH
>Mature Secondary Structure 
GSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRLLFAGLILVTFSFMHGD
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIFSILKNRKDALSLLIFSVVGALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFALA
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSAALFWGIASAFAAAFYTTWPSRLI
HCCCCCHHHHHHHHHHHHHHHEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLILAFFYLVVIGTSLTFSLYLKGA
HHHCCCCEEECCCCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCH
QLIGGPKASILSCAEPLSSALLSLLLLGISFTLPDWLGTLLILSSVILISLDSRRRARAA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677609; 9311997