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The map label for this gene is rhmR [H]

Identifier: 16766819

GI number: 16766819

Start: 3697979

End: 3698734

Strand: Reverse

Name: rhmR [H]

Synonym: STM3533

Alternate gene names: 16766819

Gene position: 3698734-3697979 (Counterclockwise)

Preceding gene: 16766820

Following gene: 16766816

Centisome position: 76.15

GC content: 50.53

Gene sequence:

>756_bases
ATGAAAAAGATTACGACATCTATTCCGGCTCTCGATAAAATTATGCGCGTATTTGCTTACCTTCTGGAGTGCGATGGCGC
AACGTTTACCCAGATCCATCAAAATTCAGGGATTGCGAAAAGCAGTACCTCATCTTTGCTCAACGGCATGGTGGAGCATG
GGTTATTACGCCAGGAAAAAGACAAGTATTATCTGGGGCTACGCCTGTATGAATTAGGTAATAAAGCGGCGGAACAGTAC
GATATTAAAAAAATCGCGTTACCGATTCTTGAAGAGATTCGCGATAACACCGGCCTGACCTGCCATCTTGGCGTTCTGGA
GGGCGATGCCCCTATTTACCTTCTGAAAGTCGAAAGCCCACAGGCTATTGTGATTCGAAGCTGGGAGGGCAAGCGCCTCT
CATTACATAGCTCAGGGCTGGGAAAGGTGCTGATTGCATGGCTTAGCGGGGAAGAGCTGGAGGAGTTGCTGCCTCCAGAT
CAGATATTAACGCGTTTTACGGATACGACGATCACGGATGTGAATATCCTTAAGCAGGAGTTAGCAGGAATTCGCCGTCG
CGGCTGGGGTTATGATAACGAAGAAGACTCCCTTGGCGTGCGCTGCATTGCGGTGCCGGTATTCAATACGCAGGGGAAAG
TGATCGCCGCCCTGAGCGTATCCGGCGTTACGTTCCAGATCCCCGATGATAAACGCGAGTCGCTTGCTACGCTGATGATG
GATGCCAGCCGTAGCCTGACGCGTCTGATGTGCTGA

Upstream 100 bases:

>100_bases
CTGCTGAATCTGTTAGCGGCACTTGGTCTCTGTCATGGAAAAAGGGTCGAGTACTGGTGTATAGTATTAGCAGAAAAATC
CATAATTAATTGATAATAAT

Downstream 100 bases:

>100_bases
AATAAAAAGACATAGCGGGCAAGAAGCCCGCTTTCGTCATCGCTTAAAGTCCCGCACGCTGTAAGATCTGCTTCAAATTC
GAAATATGTTCTTCATTTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKKITTSIPALDKIMRVFAYLLECDGATFTQIHQNSGIAKSSTSSLLNGMVEHGLLRQEKDKYYLGLRLYELGNKAAEQY
DIKKIALPILEEIRDNTGLTCHLGVLEGDAPIYLLKVESPQAIVIRSWEGKRLSLHSSGLGKVLIAWLSGEELEELLPPD
QILTRFTDTTITDVNILKQELAGIRRRGWGYDNEEDSLGVRCIAVPVFNTQGKVIAALSVSGVTFQIPDDKRESLATLMM
DASRSLTRLMC

Sequences:

>Translated_251_residues
MKKITTSIPALDKIMRVFAYLLECDGATFTQIHQNSGIAKSSTSSLLNGMVEHGLLRQEKDKYYLGLRLYELGNKAAEQY
DIKKIALPILEEIRDNTGLTCHLGVLEGDAPIYLLKVESPQAIVIRSWEGKRLSLHSSGLGKVLIAWLSGEELEELLPPD
QILTRFTDTTITDVNILKQELAGIRRRGWGYDNEEDSLGVRCIAVPVFNTQGKVIAALSVSGVTFQIPDDKRESLATLMM
DASRSLTRLMC
>Mature_251_residues
MKKITTSIPALDKIMRVFAYLLECDGATFTQIHQNSGIAKSSTSSLLNGMVEHGLLRQEKDKYYLGLRLYELGNKAAEQY
DIKKIALPILEEIRDNTGLTCHLGVLEGDAPIYLLKVESPQAIVIRSWEGKRLSLHSSGLGKVLIAWLSGEELEELLPPD
QILTRFTDTTITDVNILKQELAGIRRRGWGYDNEEDSLGVRCIAVPVFNTQGKVIAALSVSGVTFQIPDDKRESLATLMM
DASRSLTRLMC

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788581, Length=250, Percent_Identity=38.8, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1790752, Length=249, Percent_Identity=35.7429718875502, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786468, Length=224, Percent_Identity=38.8392857142857, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788131, Length=252, Percent_Identity=32.9365079365079, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI87082359, Length=248, Percent_Identity=28.2258064516129, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786715, Length=241, Percent_Identity=26.9709543568465, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789999, Length=201, Percent_Identity=31.3432835820896, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27896; Mature: 27896

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITTSIPALDKIMRVFAYLLECDGATFTQIHQNSGIAKSSTSSLLNGMVEHGLLRQEK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCC
DKYYLGLRLYELGNKAAEQYDIKKIALPILEEIRDNTGLTCHLGVLEGDAPIYLLKVESP
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCC
QAIVIRSWEGKRLSLHSSGLGKVLIAWLSGEELEELLPPDQILTRFTDTTITDVNILKQE
CEEEEECCCCCEEEECCCCCCEEEEEECCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHH
LAGIRRRGWGYDNEEDSLGVRCIAVPVFNTQGKVIAALSVSGVTFQIPDDKRESLATLMM
HHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCEEEECCCCHHHHHHHHHH
DASRSLTRLMC
HHHHHHHHHCC
>Mature Secondary Structure
MKKITTSIPALDKIMRVFAYLLECDGATFTQIHQNSGIAKSSTSSLLNGMVEHGLLRQEK
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCC
DKYYLGLRLYELGNKAAEQYDIKKIALPILEEIRDNTGLTCHLGVLEGDAPIYLLKVESP
CCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCC
QAIVIRSWEGKRLSLHSSGLGKVLIAWLSGEELEELLPPDQILTRFTDTTITDVNILKQE
CEEEEECCCCCEEEECCCCCCEEEEEECCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHH
LAGIRRRGWGYDNEEDSLGVRCIAVPVFNTQGKVIAALSVSGVTFQIPDDKRESLATLMM
HHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCEEEECCCCHHHHHHHHHH
DASRSLTRLMC
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]