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The map label for this gene is atsB [H]

Identifier: 16766423

GI number: 16766423

Start: 3282394

End: 3283578

Strand: Reverse

Name: atsB [H]

Synonym: STM3123

Alternate gene names: 16766423

Gene position: 3283578-3282394 (Counterclockwise)

Preceding gene: 16766425

Following gene: 16766422

Centisome position: 67.6

GC content: 49.87

Gene sequence:

>1185_bases
ATGTTGAATCTCAACACATTACGGCAACAACAAATCCCCGTAATGACGGAATATCGCGCGCAGATACCCTTTCATATTCT
GGCAAAGCCCATAGGCCCTGCATGTAATCTGGCCTGCCGCTATTGTTATTATCCACAGGGCGAAACGCCCGTAGAAAAAA
TGAATGAATCAACGCTGGAGATTTTTATTTGTCGCTATATTGCGGCGCAACCTGCCAGTGCGCGTGAAATTAATTTTGTC
TGGCAAGGCGGTGAACCGCTTTTAGCCGGAATCGGTTTTTATAAAAAGGTAATAGCGCTTCAACAACGATATGCGCCTGA
CGGCGTGACGATCAGTAATAGTCTGCAAACGAATGCGACGTTGTTAAACGATGCCTGGTGCCGTCTGTTTCGCGACAATA
ATTTTACTATTGGCATCAGTCTTGAGGGCAGTGAAGACTTGCAAAATCATCATCGTCCGGGCAAACGCGGCGAGGCCAGC
TATCCGGCGGTGTTGCGGGGAATCACATTGTTACAACACTATCGAGTCGATTTTAATGTACTGATTGTCGTGCATGATGA
CATGGCTCGCCATGCGGCAGCCATCTACGATCATGTTGTTAGCCTTGGCGTTCGTTATCTGCAATTTCAGCCACTGATGA
ACGAAGGCAACGCCCTACAGCAACGTTACCAATTGAGTGCGGATAACTGGGGACGTTTCATGATTGATATCTGGCGTCAA
TGGCGCAAACGCGGCGATATGGGACGGGTTTTTGTGATCAACATTGAACAGGCATGGGCACAATATTTTACGCATATCAG
CGCCACCTGTGTCCATTCCGCCCGCTGCGGAACGAATCTGGTCATGGAGCCGGACGGCAAACTCTATGCCTGCGATCATC
TGATTAATAGCCAGCATTACCTGGGACAGCTTGCTAATAATACGTTAGCGCCAGCCGTAGATTCCGCAACCCGGCTTCCC
TTTGGTATTAAGAAAAGCCAGCGCCGGGAGTGTCAACGGTGTTCTGTGAAAATAGTCTGCCAGGGAGGCTGCCCCGCACA
TATCAACAGTGCCGGCTACAACCGACTTTGTAGCGGCTATTACTCTTTTTTCACGGAGATTCTGGCTCCGCTACGCGCCT
GGCCCCGGGATCTGAATGGACTGAAAGCCTGGCGTGCTGACGTTATGGGTAGATTTTCGGGCTGA

Upstream 100 bases:

>100_bases
ACAGCCTGCTCTCGGCATTCTGCCCGCAGCGCCAGACGAACGCTATTGCGAAATGTGAGTCATGTCTCCGCATCAGAAAT
GATAACTACAGGACAGAATA

Downstream 100 bases:

>100_bases
TGGTTCCTCTTGCCGCATTTGCCCGCCGCTCTTGTACAACATCCGTAGTCTGAAATGGAGAATAAGCCGTGAAAAAAGAA
GTAACACTTGCCACACTTAG

Product: arylsulfatase regulator

Products: NA

Alternate protein names: AnSME; Arylsulfatase-activating protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MLNLNTLRQQQIPVMTEYRAQIPFHILAKPIGPACNLACRYCYYPQGETPVEKMNESTLEIFICRYIAAQPASAREINFV
WQGGEPLLAGIGFYKKVIALQQRYAPDGVTISNSLQTNATLLNDAWCRLFRDNNFTIGISLEGSEDLQNHHRPGKRGEAS
YPAVLRGITLLQHYRVDFNVLIVVHDDMARHAAAIYDHVVSLGVRYLQFQPLMNEGNALQQRYQLSADNWGRFMIDIWRQ
WRKRGDMGRVFVINIEQAWAQYFTHISATCVHSARCGTNLVMEPDGKLYACDHLINSQHYLGQLANNTLAPAVDSATRLP
FGIKKSQRRECQRCSVKIVCQGGCPAHINSAGYNRLCSGYYSFFTEILAPLRAWPRDLNGLKAWRADVMGRFSG

Sequences:

>Translated_394_residues
MLNLNTLRQQQIPVMTEYRAQIPFHILAKPIGPACNLACRYCYYPQGETPVEKMNESTLEIFICRYIAAQPASAREINFV
WQGGEPLLAGIGFYKKVIALQQRYAPDGVTISNSLQTNATLLNDAWCRLFRDNNFTIGISLEGSEDLQNHHRPGKRGEAS
YPAVLRGITLLQHYRVDFNVLIVVHDDMARHAAAIYDHVVSLGVRYLQFQPLMNEGNALQQRYQLSADNWGRFMIDIWRQ
WRKRGDMGRVFVINIEQAWAQYFTHISATCVHSARCGTNLVMEPDGKLYACDHLINSQHYLGQLANNTLAPAVDSATRLP
FGIKKSQRRECQRCSVKIVCQGGCPAHINSAGYNRLCSGYYSFFTEILAPLRAWPRDLNGLKAWRADVMGRFSG
>Mature_394_residues
MLNLNTLRQQQIPVMTEYRAQIPFHILAKPIGPACNLACRYCYYPQGETPVEKMNESTLEIFICRYIAAQPASAREINFV
WQGGEPLLAGIGFYKKVIALQQRYAPDGVTISNSLQTNATLLNDAWCRLFRDNNFTIGISLEGSEDLQNHHRPGKRGEAS
YPAVLRGITLLQHYRVDFNVLIVVHDDMARHAAAIYDHVVSLGVRYLQFQPLMNEGNALQQRYQLSADNWGRFMIDIWRQ
WRKRGDMGRVFVINIEQAWAQYFTHISATCVHSARCGTNLVMEPDGKLYACDHLINSQHYLGQLANNTLAPAVDSATRLP
FGIKKSQRRECQRCSVKIVCQGGCPAHINSAGYNRLCSGYYSFFTEILAPLRAWPRDLNGLKAWRADVMGRFSG

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of serine ('Ser-72' in the arylsulfatase AtsA) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemica

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=387, Percent_Identity=36.4341085271318, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI87081923, Length=368, Percent_Identity=33.695652173913, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 44695; Mature: 44695

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLNTLRQQQIPVMTEYRAQIPFHILAKPIGPACNLACRYCYYPQGETPVEKMNESTLE
CCCCHHHHHHCCCCHHHHHHCCCHHEEECCCCCHHHHHEEEEECCCCCCCHHHHCCHHHH
IFICRYIAAQPASAREINFVWQGGEPLLAGIGFYKKVIALQQRYAPDGVTISNSLQTNAT
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHH
LLNDAWCRLFRDNNFTIGISLEGSEDLQNHHRPGKRGEASYPAVLRGITLLQHYRVDFNV
HHHHHHHHHEECCCEEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
LIVVHDDMARHAAAIYDHVVSLGVRYLQFQPLMNEGNALQQRYQLSADNWGRFMIDIWRQ
EEEEECCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHH
WRKRGDMGRVFVINIEQAWAQYFTHISATCVHSARCGTNLVMEPDGKLYACDHLINSQHY
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEHHHHCCHHH
LGQLANNTLAPAVDSATRLPFGIKKSQRRECQRCSVKIVCQGGCPAHINSAGYNRLCSGY
HHHHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHH
YSFFTEILAPLRAWPRDLNGLKAWRADVMGRFSG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLNLNTLRQQQIPVMTEYRAQIPFHILAKPIGPACNLACRYCYYPQGETPVEKMNESTLE
CCCCHHHHHHCCCCHHHHHHCCCHHEEECCCCCHHHHHEEEEECCCCCCCHHHHCCHHHH
IFICRYIAAQPASAREINFVWQGGEPLLAGIGFYKKVIALQQRYAPDGVTISNSLQTNAT
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHH
LLNDAWCRLFRDNNFTIGISLEGSEDLQNHHRPGKRGEASYPAVLRGITLLQHYRVDFNV
HHHHHHHHHEECCCEEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
LIVVHDDMARHAAAIYDHVVSLGVRYLQFQPLMNEGNALQQRYQLSADNWGRFMIDIWRQ
EEEEECCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHH
WRKRGDMGRVFVINIEQAWAQYFTHISATCVHSARCGTNLVMEPDGKLYACDHLINSQHY
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEHHHHCCHHH
LGQLANNTLAPAVDSATRLPFGIKKSQRRECQRCSVKIVCQGGCPAHINSAGYNRLCSGY
HHHHHCCCCCCCCCCHHCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHH
YSFFTEILAPLRAWPRDLNGLKAWRADVMGRFSG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180918 [H]