Click here to switch to the map view.

The map label for this gene is yjjN [H]

Identifier: 16766383

GI number: 16766383

Start: 3243347

End: 3244363

Strand: Reverse

Name: yjjN [H]

Synonym: STM3082

Alternate gene names: 16766383

Gene position: 3244363-3243347 (Counterclockwise)

Preceding gene: 16766384

Following gene: 16766382

Centisome position: 66.79

GC content: 51.72

Gene sequence:

>1017_bases
ATGAAAACGCTTATCTGTAATAATCCGGGAAATATCGAATACATTGAAAGGGATATTCCTCATTTAAAAGACGATGAAGT
ACTGTTAAAAATTAAAGCGGTTGGTATTTGCGGCACCGATATCCATGCGTTTGCCGGTCGCCAGCCCTTTTTTGCCTATC
CGCGCGTGCTGGGTCATGAAATTTGCGGCGTGGCTGAAATGTTAGGTAAATCGTGCAGCACGGCGAAGGTCGGCCAACGC
TATAGCGTTATTCCCTGTATTCCTTGCGGCGCTTGCGCAGCCTGCCGGGAAGGAAAAACCAACTGCTGTGAGAACGTCTC
GCTGTATGGTGTTCACCAGGACGGCGGCTTTAGCGAATATCTGGCCGTTCGTGAACAAAATCTGGTTGAACTGTCGGATA
ACCTCACTGACAGCGCGGGCGCGCTGGTTGAGTGTTTCGCCATCAGCGCCCATGCAGTACGCCGCGCTGACGTGAAGCCG
CAGCAAAACATTGTGGTGGTCGGCGCCGGGCCGATTGGGCTGGCCGCCGCCGCGATAGCAAAAGCCAAAGGCGCTCGCGT
CGCGGTAGCTGATATTGACGCCGAACGCCGTCGTCTGGTCGCCGAAAAGGTAGGCGTTGCAACGCTCGATCCGTCGTCAG
ACGACTATATTGATGCGCTGAAAGCCTGTTTCTCCGGTGAATTAGCCGGCACTGTGCTTGATGCCACCGGCAATAAATCC
TCCATGAGCCGCGCTGTCGATCTGATTCGTCACGGCGGAAAAATCGTCTTCATCGGGCTGTATATCGGCGAGCTCGTCAT
TGACGATCCGACCTTCCATAAAAAAGAGACCACGCTATTGAGCAGCCGTAACGCGACGCGGGAAGACTTCGAATGTGTCA
TTGAGCTAATGGCTCAGGGCGCTATTAGCGAAACAATGATGAAAAACCAGGAATTCGATTTCTATACGTTCGGCAACCAG
TACCAGAAGAACGTGGTAGAAAACAAAAAATTGGTTAAAGGCGTTATCAAATTTTAA

Upstream 100 bases:

>100_bases
ACAACGCAGACTTTTTAAACAACATTCAGCAGGCCTTTAACCATATTGAATTACATGGCGTCACGGCCACCATTCACCGT
TTATCTTCAAAGGGTTAAGT

Downstream 100 bases:

>100_bases
TAGCGGGATAGTTATGTCAACAATATTAGTCAAAGAAAATGAATTGAAAGCGCTGGCGTTTAATAAACTCACCCAGGCGG
GTCTTGACGCGCAAACGGCG

Product: zinc-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKTLICNNPGNIEYIERDIPHLKDDEVLLKIKAVGICGTDIHAFAGRQPFFAYPRVLGHEICGVAEMLGKSCSTAKVGQR
YSVIPCIPCGACAACREGKTNCCENVSLYGVHQDGGFSEYLAVREQNLVELSDNLTDSAGALVECFAISAHAVRRADVKP
QQNIVVVGAGPIGLAAAAIAKAKGARVAVADIDAERRRLVAEKVGVATLDPSSDDYIDALKACFSGELAGTVLDATGNKS
SMSRAVDLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFECVIELMAQGAISETMMKNQEFDFYTFGNQ
YQKNVVENKKLVKGVIKF

Sequences:

>Translated_338_residues
MKTLICNNPGNIEYIERDIPHLKDDEVLLKIKAVGICGTDIHAFAGRQPFFAYPRVLGHEICGVAEMLGKSCSTAKVGQR
YSVIPCIPCGACAACREGKTNCCENVSLYGVHQDGGFSEYLAVREQNLVELSDNLTDSAGALVECFAISAHAVRRADVKP
QQNIVVVGAGPIGLAAAAIAKAKGARVAVADIDAERRRLVAEKVGVATLDPSSDDYIDALKACFSGELAGTVLDATGNKS
SMSRAVDLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFECVIELMAQGAISETMMKNQEFDFYTFGNQ
YQKNVVENKKLVKGVIKF
>Mature_338_residues
MKTLICNNPGNIEYIERDIPHLKDDEVLLKIKAVGICGTDIHAFAGRQPFFAYPRVLGHEICGVAEMLGKSCSTAKVGQR
YSVIPCIPCGACAACREGKTNCCENVSLYGVHQDGGFSEYLAVREQNLVELSDNLTDSAGALVECFAISAHAVRRADVKP
QQNIVVVGAGPIGLAAAAIAKAKGARVAVADIDAERRRLVAEKVGVATLDPSSDDYIDALKACFSGELAGTVLDATGNKS
SMSRAVDLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFECVIELMAQGAISETMMKNQEFDFYTFGNQ
YQKNVVENKKLVKGVIKF

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=279, Percent_Identity=30.8243727598566, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4501939, Length=226, Percent_Identity=27.4336283185841, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI156523966, Length=226, Percent_Identity=27.4336283185841, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI71743840, Length=215, Percent_Identity=31.6279069767442, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI262073058, Length=215, Percent_Identity=31.6279069767442, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4501929, Length=236, Percent_Identity=32.2033898305085, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI34577061, Length=234, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI71565154, Length=215, Percent_Identity=30.6976744186047, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI71565152, Length=288, Percent_Identity=26.7361111111111, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4501933, Length=236, Percent_Identity=29.2372881355932, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI194239674, Length=281, Percent_Identity=23.8434163701068, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI13236495, Length=281, Percent_Identity=23.8434163701068, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI226510992, Length=338, Percent_Identity=54.7337278106509, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1787863, Length=319, Percent_Identity=33.2288401253918, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788073, Length=344, Percent_Identity=32.2674418604651, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1790045, Length=255, Percent_Identity=32.156862745098, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI87082125, Length=278, Percent_Identity=32.3741007194245, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788407, Length=338, Percent_Identity=25.7396449704142, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790718, Length=306, Percent_Identity=27.4509803921569, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788075, Length=317, Percent_Identity=27.4447949526814, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081918, Length=337, Percent_Identity=25.5192878338279, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786825, Length=315, Percent_Identity=26.3492063492064, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1786552, Length=284, Percent_Identity=28.169014084507, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082401, Length=138, Percent_Identity=31.8840579710145, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=253, Percent_Identity=32.4110671936759, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17562878, Length=233, Percent_Identity=32.1888412017167, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17562584, Length=302, Percent_Identity=29.1390728476821, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988145, Length=300, Percent_Identity=26.3333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562582, Length=301, Percent_Identity=28.9036544850498, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI25146526, Length=277, Percent_Identity=24.9097472924188, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71997431, Length=277, Percent_Identity=23.826714801444, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=341, Percent_Identity=28.1524926686217, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319257, Length=338, Percent_Identity=28.1065088757396, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6319955, Length=341, Percent_Identity=28.1524926686217, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323099, Length=323, Percent_Identity=28.4829721362229, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319258, Length=242, Percent_Identity=30.1652892561983, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6319621, Length=305, Percent_Identity=26.8852459016393, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=309, Percent_Identity=24.5954692556634, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323961, Length=304, Percent_Identity=25.6578947368421, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=285, Percent_Identity=28.4210526315789, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=306, Percent_Identity=26.4705882352941, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323980, Length=272, Percent_Identity=30.1470588235294, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319949, Length=294, Percent_Identity=25.8503401360544, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737897, Length=240, Percent_Identity=34.1666666666667, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17137530, Length=332, Percent_Identity=30.1204819277108, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI221457811, Length=260, Percent_Identity=29.2307692307692, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45551930, Length=260, Percent_Identity=29.2307692307692, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45550770, Length=260, Percent_Identity=29.2307692307692, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI17737895, Length=290, Percent_Identity=27.2413793103448, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 36498; Mature: 36498

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLICNNPGNIEYIERDIPHLKDDEVLLKIKAVGICGTDIHAFAGRQPFFAYPRVLGHE
CCEEEECCCCCCEEECCCCCCCCCCCEEEEEEEEEEECCCHHHHCCCCCCHHHHHHHHHH
ICGVAEMLGKSCSTAKVGQRYSVIPCIPCGACAACREGKTNCCENVSLYGVHQDGGFSEY
HHHHHHHHCCCCCCHHCCCCEEEEECCCCCHHHHHHCCCCHHHCCCEEEEEECCCCHHHH
LAVREQNLVELSDNLTDSAGALVECFAISAHAVRRADVKPQQNIVVVGAGPIGLAAAAIA
HHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHH
KAKGARVAVADIDAERRRLVAEKVGVATLDPSSDDYIDALKACFSGELAGTVLDATGNKS
HCCCCEEEEEECCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCHH
SMSRAVDLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFECVIELMAQG
HHHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCC
AISETMMKNQEFDFYTFGNQYQKNVVENKKLVKGVIKF
HHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLICNNPGNIEYIERDIPHLKDDEVLLKIKAVGICGTDIHAFAGRQPFFAYPRVLGHE
CCEEEECCCCCCEEECCCCCCCCCCCEEEEEEEEEEECCCHHHHCCCCCCHHHHHHHHHH
ICGVAEMLGKSCSTAKVGQRYSVIPCIPCGACAACREGKTNCCENVSLYGVHQDGGFSEY
HHHHHHHHCCCCCCHHCCCCEEEEECCCCCHHHHHHCCCCHHHCCCEEEEEECCCCHHHH
LAVREQNLVELSDNLTDSAGALVECFAISAHAVRRADVKPQQNIVVVGAGPIGLAAAAIA
HHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHH
KAKGARVAVADIDAERRRLVAEKVGVATLDPSSDDYIDALKACFSGELAGTVLDATGNKS
HCCCCEEEEEECCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCCCCEEEECCCCHH
SMSRAVDLIRHGGKIVFIGLYIGELVIDDPTFHKKETTLLSSRNATREDFECVIELMAQG
HHHHHHHHHHCCCEEEEEEEEECEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHCC
AISETMMKNQEFDFYTFGNQYQKNVVENKKLVKGVIKF
HHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]