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The map label for this gene is cbiO1 [H]

Identifier: 16766375

GI number: 16766375

Start: 3235022

End: 3235699

Strand: Direct

Name: cbiO1 [H]

Synonym: STM3074

Alternate gene names: 16766375

Gene position: 3235022-3235699 (Clockwise)

Preceding gene: 16766374

Following gene: 16766376

Centisome position: 66.6

GC content: 55.9

Gene sequence:

>678_bases
ATGGTTACGTTAGAGCAGTTTCGTTATCTTCCGTCCGATGCGACACGCCCGCCGGCATGTTTTGATTTCCACTATTCAAC
ACCCGGAATAGTGGCGATAGTCGGCGATAACGGCAGCGGAAAAAGTACGCTGGCGCAACTGATGGCTGGCTGGTATCCGG
ATTATCTCCCCGGTGATATTGACGGCACAGGCTTACTGCTTGGCGTCCCTATCGGGCGGCTCCCGCTGGTAGAACAGTCG
CCCACCATCCAATTGGTGCAGCAATCGCCTTATTTACAGCTTTCCGGCTGTACCTTTAGCGTAGAGGAAGAGGTGGCGTT
TGGCCCGGAGAATCTCGGCCTCCATGAAGCGGAGATTCTACGGCGCATTGACGAGGCGCTGACCCTGACAAACTGCCAGT
CGTTACGCCATCGCCATCCCGGCACGCTCTCCGGCGGCGAAACGCAGCGGGTAGTAATTGCCAGCGCGCTTGCCATGCAG
CCCAGACTGTTAATTCTTGATGAAGCCTTCAGTCGGCTGACGTCAGCGGCCACCGGGATGCTGCTGGAACGGTTACAACA
GTGGGCGCTGGAACGTCATTCTCTCATTGTGCTTTTTGAGCGTAATCATTTTCCTTTTCTGACGCGATGCCAGCGGGTAT
GGCAATTGCGCGACGGAGCGCTAACCCCATTATGTTGA

Upstream 100 bases:

>100_bases
GAGCCCGAACCACGCTGTGGGCGCCGAAAGATAGCGTGTTACAACGGGTTGCGCGGTATGGCATGGTACTGCTAATACTG
GCGGAAGCGGGAGTATGGAT

Downstream 100 bases:

>100_bases
CGTTAAATCAGGTCGCTTATCGCTGGCCGGATGCCGCAGCCGACTGTTTGCACGCTATCTCGCTTAAACTTCGTGACGGC
GAATGGCTGGCGTTGACCGG

Product: ABC-type cobalt transport system ATP-binding component

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVEQS
PTIQLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQ
PRLLILDEAFSRLTSAATGMLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRDGALTPLC

Sequences:

>Translated_225_residues
MVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVEQS
PTIQLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQ
PRLLILDEAFSRLTSAATGMLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRDGALTPLC
>Mature_225_residues
MVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVEQS
PTIQLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQ
PRLLILDEAFSRLTSAATGMLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRDGALTPLC

Specific function: Part of the ABC transporter complex CbiONQ involved in cobalt import. Responsible for energy coupling to the transport system [H]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=178, Percent_Identity=35.9550561797753, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI4505771, Length=178, Percent_Identity=33.1460674157303, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI9961252, Length=178, Percent_Identity=33.1460674157303, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI9961250, Length=181, Percent_Identity=33.7016574585635, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=166, Percent_Identity=33.7349397590361, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=214, Percent_Identity=31.3084112149533, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786653, Length=202, Percent_Identity=31.1881188118812, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787029, Length=181, Percent_Identity=30.3867403314917, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789891, Length=202, Percent_Identity=33.1683168316832, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789032, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=172, Percent_Identity=30.8139534883721, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788450, Length=177, Percent_Identity=30.5084745762712, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787792, Length=203, Percent_Identity=30.5418719211823, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786398, Length=228, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788761, Length=169, Percent_Identity=28.4023668639053, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87081709, Length=162, Percent_Identity=28.3950617283951, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=31.2796208530806, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=205, Percent_Identity=33.6585365853659, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565938, Length=179, Percent_Identity=35.195530726257, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17533971, Length=178, Percent_Identity=33.1460674157303, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=193, Percent_Identity=33.160621761658, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17541710, Length=172, Percent_Identity=33.7209302325581, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17567269, Length=174, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=174, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534520, Length=177, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=178, Percent_Identity=31.4606741573034, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569145, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=200, Percent_Identity=29.5, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=202, Percent_Identity=29.7029702970297, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=202, Percent_Identity=29.7029702970297, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=202, Percent_Identity=29.7029702970297, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574744, Length=176, Percent_Identity=28.4090909090909, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24653245, Length=153, Percent_Identity=34.640522875817, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281363262, Length=153, Percent_Identity=34.640522875817, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136662, Length=203, Percent_Identity=33.4975369458128, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015856
- InterPro:   IPR003593
- InterPro:   IPR022112 [H]

Pfam domain/function: PF00005 ABC_tran; PF12370 CoABC_C [H]

EC number: NA

Molecular weight: Translated: 24940; Mature: 24940

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDI
CCCHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
DGTGLLLGVPIGRLPLVEQSPTIQLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEIL
CCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCEEEECHHHHCCCCCCCCCHHHHH
RRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQPRLLILDEAFSRLTSAATGM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHH
LLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRDGALTPLC
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDI
CCCHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
DGTGLLLGVPIGRLPLVEQSPTIQLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEIL
CCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCEEEECHHHHCCCCCCCCCHHHHH
RRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQPRLLILDEAFSRLTSAATGM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHH
LLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRDGALTPLC
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA