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The map label for this gene is sipD

Identifier: 16766189

GI number: 16766189

Start: 3026755

End: 3027786

Strand: Reverse

Name: sipD

Synonym: STM2883

Alternate gene names: 16766189

Gene position: 3027786-3026755 (Counterclockwise)

Preceding gene: 16766190

Following gene: 16766188

Centisome position: 62.33

GC content: 47.29

Gene sequence:

>1032_bases
ATGCTTAATATTCAAAATTATTCCGCTTCTCCTCATCCGGGGATCGTTGCCGAACGGCCGCAGACTCCCTCGGCGAGCGA
GCACGTCGAGACTGCCGTGGTACCGTCTACCACAGAACATCGCGGTACAGATATCATTTCATTATCGCAGGCGGCTACTA
AAATCCACCAGGCACAGCAGACGCTGCAGTCAACGCCACCGATCTCTGAAGAGAATAATGACGAGCGCACGCTGGCGCGC
CAGCAGTTGACCAGCAGCCTGAATGCGCTGGCGAAGTCCGGCGTGTCATTATCCGCAGAACAAAATGAGAACCTGCGGAG
CGCGTTTTCTGCGCCGACGTCGGCCTTATTTAGCGCTTCGCCTATGGCGCAGCCGAGAACAACCATTTCTGATGCTGAGA
TTTGGGATATGGTTTCCCAAAATATATCGGCGATAGGTGACAGCTATCTGGGCGTTTATGAAAACGTTGTCGCAGTCTAT
ACCGATTTTTATCAGGCCTTCAGTGATATTCTTTCCAAAATGGGAGGCTGGTTATTACCAGGTAAGGACGGTAATACCGT
TAAGCTAGATGTTACCTCACTCAAAAATGATTTAAACAGTTTAGTCAATAAATATAATCAAATAAACAGTAATACCGTTT
TATTTCCAGCGCAGTCAGGCAGCGGCGTTAAAGTAGCCACTGAAGCGGAAGCGAGACAGTGGCTCAGTGAATTGAATTTA
CCGAATAGCTGCCTGAAATCTTATGGATCCGGTTATGTCGTCACCGTTGATCTGACGCCATTACAAAAAATGGTTCAGGA
TATTGATGGTTTAGGCGCGCCGGGAAAAGACTCAAAACTCGAAATGGATAACGCCAAATATCAAGCCTGGCAGTCGGGTT
TTAAAGCGCAGGAAGAAAATATGAAAACCACATTACAGACGCTGACGCAAAAATATAGCAATGCCAATTCATTGTACGAC
AACCTGGTAAAAGTGCTGAGCAGTACGATAAGTAGCAGCCTGGAAACCGCCAAAAGCTTCCTGCAAGGATAA

Upstream 100 bases:

>100_bases
GCTGCTATCGCAGGCAATATTCGCGCTTAATCTGAAAGGTCATCTATACGCCATCATGGGTGTGATTTAATCGCGCTCCT
GATGGCGAACTGGGGATATT

Downstream 100 bases:

>100_bases
CAGAAGAGGATATTAATAATGGTTACAAGTGTAAGGACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAA
AACGCAGGCCACGAATCTTG

Product: translocation machinery component

Products: NA

Alternate protein names: Salmonella invasion protein D

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIHQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLLPGKDGNTVKLDVTSLKNDLNSLVNKYNQINSNTVLFPAQSGSGVKVATEAEARQWLSELNL
PNSCLKSYGSGYVVTVDLTPLQKMVQDIDGLGAPGKDSKLEMDNAKYQAWQSGFKAQEENMKTTLQTLTQKYSNANSLYD
NLVKVLSSTISSSLETAKSFLQG

Sequences:

>Translated_343_residues
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIHQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLLPGKDGNTVKLDVTSLKNDLNSLVNKYNQINSNTVLFPAQSGSGVKVATEAEARQWLSELNL
PNSCLKSYGSGYVVTVDLTPLQKMVQDIDGLGAPGKDSKLEMDNAKYQAWQSGFKAQEENMKTTLQTLTQKYSNANSLYD
NLVKVLSSTISSSLETAKSFLQG
>Mature_343_residues
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIHQAQQTLQSTPPISEENNDERTLAR
QQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
TDFYQAFSDILSKMGGWLLPGKDGNTVKLDVTSLKNDLNSLVNKYNQINSNTVLFPAQSGSGVKVATEAEARQWLSELNL
PNSCLKSYGSGYVVTVDLTPLQKMVQDIDGLGAPGKDSKLEMDNAKYQAWQSGFKAQEENMKTTLQTLTQKYSNANSLYD
NLVKVLSSTISSSLETAKSFLQG

Specific function: Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of sipA, sipB, and sipC

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the invasin protein D family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SIPD_SALTY (Q56026)

Other databases:

- EMBL:   U30491
- EMBL:   U40013
- EMBL:   AE006468
- PIR:   S70549
- RefSeq:   NP_461804.1
- ProteinModelPortal:   Q56026
- SMR:   Q56026
- PRIDE:   Q56026
- GeneID:   1254406
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2883
- NMPDR:   fig|99287.1.peg.2780
- HOGENOM:   HBG671452
- OMA:   NYLGVYE
- ProtClustDB:   PRK15330
- BioCyc:   STYP99287:STM2883-MONOMER
- GO:   GO:0009405
- InterPro:   IPR009483
- InterPro:   IPR013386
- TIGRFAMs:   TIGR02553

Pfam domain/function: PF06511 IpaD

EC number: NA

Molecular weight: Translated: 37113; Mature: 37113

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIHQAQQ
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSAS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHCCC
PMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLLP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
GKDGNTVKLDVTSLKNDLNSLVNKYNQINSNTVLFPAQSGSGVKVATEAEARQWLSELNL
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECHHHHHHHHHHCCC
PNSCLKSYGSGYVVTVDLTPLQKMVQDIDGLGAPGKDSKLEMDNAKYQAWQSGFKAQEEN
CHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MKTTLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNIQNYSASPHPGIVAERPQTPSASEHVETAVVPSTTEHRGTDIISLSQAATKIHQAQQ
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQNENLRSAFSAPTSALFSAS
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHCCC
PMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVYTDFYQAFSDILSKMGGWLLP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
GKDGNTVKLDVTSLKNDLNSLVNKYNQINSNTVLFPAQSGSGVKVATEAEARQWLSELNL
CCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEECHHHHHHHHHHCCC
PNSCLKSYGSGYVVTVDLTPLQKMVQDIDGLGAPGKDSKLEMDNAKYQAWQSGFKAQEEN
CHHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MKTTLQTLTQKYSNANSLYDNLVKVLSSTISSSLETAKSFLQG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748032; 8522512; 11677609; 10692170