Click here to switch to the map view.

The map label for this gene is emrR [H]

Identifier: 16766124

GI number: 16766124

Start: 2961121

End: 2961651

Strand: Direct

Name: emrR [H]

Synonym: STM2813

Alternate gene names: 16766124

Gene position: 2961121-2961651 (Clockwise)

Preceding gene: 16766123

Following gene: 16766125

Centisome position: 60.96

GC content: 48.78

Gene sequence:

>531_bases
ATGGATAGTTCGTTTACGCCCATTGAACAAATGCTAAAATTTCGCGCCAGCCGTCACGAAGACTTTCCTTATCAGGAAAT
TCTTTTGACTCGTCTTTGTATGCACATGCAAGGCAAGCTCCTGGAAAACCGCAATAAGATGCTGAAGGCTCAAGGGATTA
ACGAGACGTTGTTTATGGCGTTGATTACGCTGGAGTCTCAGGAAAACCACAGTATTCAGCCGTCTGAATTAAGCTGCGCG
CTGGGTTCATCTCGCACCAATGCGACACGCATTGCAGATGAGCTGGAAAAACGCGGCTGGATTGAGCGTCGTGAGAGCGA
TAACGACCGCCGTTGCCTGCATCTGCAATTAACGGAGAAAGGCCAGGCATTTTTGCAAGAAGTGCTTCCGCCTCAGCATC
ATTGTCTGCATCAACTCTGGTCATCACTTAGCACAGCCGAAAAAGATCAACTTGAGCACATCACTCGTAAACTCCTGACG
CGTCTTGATCAAATGGAGCAGGAAGGCACTGTTCTTGAGGCGCTGCGCTAA

Upstream 100 bases:

>100_bases
TGCTTTATAGCCTGAAAGAATGATTTTGTATTAATAATACATTTACTTTATTTGTCACTGTCGTTACTATATCGGCTGAA
ATTAATGAGGTCATGCCCAA

Downstream 100 bases:

>100_bases
AGCGCCGACCCGCTCAAAAATCCAGATTAATAACAGGAAAGCGGACAGGCCGGCACGCGTTACTGCTGGCCTTTCTGACA
ACAGGTCGGCTCAGCCGATG

Product: transcriptional repressor MprA

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA
LGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGQAFLQEVLPPQHHCLHQLWSSLSTAEKDQLEHITRKLLT
RLDQMEQEGTVLEALR

Sequences:

>Translated_176_residues
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA
LGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGQAFLQEVLPPQHHCLHQLWSSLSTAEKDQLEHITRKLLT
RLDQMEQEGTVLEALR
>Mature_176_residues
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA
LGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGQAFLQEVLPPQHHCLHQLWSSLSTAEKDQLEHITRKLLT
RLDQMEQEGTVLEALR

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=175, Percent_Identity=93.1428571428571, Blast_Score=337, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 20538; Mature: 20538

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMA
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEK
HHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEECHH
GQAFLQEVLPPQHHCLHQLWSSLSTAEKDQLEHITRKLLTRLDQMEQEGTVLEALR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQGKLLENRNKMLKAQGINETLFMA
CCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEK
HHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEECHH
GQAFLQEVLPPQHHCLHQLWSSLSTAEKDQLEHITRKLLTRLDQMEQEGTVLEALR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]