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The map label for this gene is yfiC

Identifier: 16765962

GI number: 16765962

Start: 2782035

End: 2782772

Strand: Reverse

Name: yfiC

Synonym: STM2642

Alternate gene names: 16765962

Gene position: 2782772-2782035 (Counterclockwise)

Preceding gene: 16765964

Following gene: 16765960

Centisome position: 57.29

GC content: 53.66

Gene sequence:

>738_bases
ATGTCTCAGTCTGGCTCCGTTCTTCGTCGTAACGGATTTACGTTTAAACAGTTTTTTGTCGCACACGATCGGTGTGCGAT
GAAAGTGGGAACTGACGGTATTTTACTCGGGGCGTGGGCGCCGGTCGCGGATGTAAAGCGAATTCTGGATATCGGTACTG
GAAGCGGTCTGCTGGCGTTAATGCTGGCGCAGCGGACGGATGACAATGTGCCTATTGACGCCGTGGAACTGGATGCCGGG
GCTGCCATGCAAGCGCAGGAAAACGTTGCTCACTCTCCCTGGCCGCATCGAATAACGGTGCATACTGACGATATTCAGCG
TTGGGCGCCTCGCCAGACGGTACGCTTTGATCTTATTATCAGCAACCCGCCTTATTACGAACCCGGTGTGGAATGCGCCA
CGCCGCAGCGGGAGCAGGCGCGTTACACCGCTACGCTGGATCACCAGACGTTATTGGCTATTGCGGCGGATTGTATTACC
GAAGATGGCTTTTTTTGCGTAGTCTTGCCGGAACAAATAGGTAACGCTTTTACGCAGCAAGCGCTCAACATGGGATGGCA
TTTGCGGCTACGTACTGACGTTGCGGAAAACGAAGCGCGCTTGCCGCACCGGGTTTTGCTCGCATTCTCCCCGCAAGCCG
GGGAGTGCTTTAGCGACAGATTAGTAATTCGCGGGTCAGACCAGCATTATTCTGAAAGTTATACGGCGCTGACCCAGGCA
TTTTATCTATTTATGTGA

Upstream 100 bases:

>100_bases
GACGTTACGGCCGCAATCTTCATCTGTTTGTATGGATATCCCTTCTCAGGTATTGTTTTCACCCGGCGCTGTCGCCGTTT
TTTTGCAAGGTTGTTTTTAC

Downstream 100 bases:

>100_bases
GGCGTTAACGGCGAAAGGATCGATGGGCCTGATTCAGCCAGTTGTTGCGGATAATCCAGCGTAAAGTGCAGCCCCCGACT
CTCTTTACGCATCATCGCAC

Product: transferase

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MSQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVADVKRILDIGTGSGLLALMLAQRTDDNVPIDAVELDAG
AAMQAQENVAHSPWPHRITVHTDDIQRWAPRQTVRFDLIISNPPYYEPGVECATPQREQARYTATLDHQTLLAIAADCIT
EDGFFCVVLPEQIGNAFTQQALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGSDQHYSESYTALTQA
FYLFM

Sequences:

>Translated_245_residues
MSQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVADVKRILDIGTGSGLLALMLAQRTDDNVPIDAVELDAG
AAMQAQENVAHSPWPHRITVHTDDIQRWAPRQTVRFDLIISNPPYYEPGVECATPQREQARYTATLDHQTLLAIAADCIT
EDGFFCVVLPEQIGNAFTQQALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGSDQHYSESYTALTQA
FYLFM
>Mature_244_residues
SQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVADVKRILDIGTGSGLLALMLAQRTDDNVPIDAVELDAGA
AMQAQENVAHSPWPHRITVHTDDIQRWAPRQTVRFDLIISNPPYYEPGVECATPQREQARYTATLDHQTLLAIAADCITE
DGFFCVVLPEQIGNAFTQQALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGSDQHYSESYTALTQAF
YLFM

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val)

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family

Homologues:

Organism=Escherichia coli, GI87082131, Length=245, Percent_Identity=84.4897959183673, Blast_Score=434, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMN6_SALCH (Q57L59)

Other databases:

- EMBL:   AE017220
- ProteinModelPortal:   Q57L59
- GenomeReviews:   AE017220_GR
- KEGG:   sec:SC2647
- NMPDR:   fig|321314.4.peg.3099
- HOGENOM:   HBG307609
- OMA:   FKQFHIN
- ProtClustDB:   CLSK2391290
- BioCyc:   SENT321314:SCH_2647-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01872
- InterPro:   IPR002052
- InterPro:   IPR007848
- InterPro:   IPR022882

Pfam domain/function: PF05175 MTS

EC number: =2.1.1.55

Molecular weight: Translated: 27307; Mature: 27176

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVADVKRILDIGTGSGLLAL
CCCCCCEEECCCCCHHHHHHHHCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHH
MLAQRTDDNVPIDAVELDAGAAMQAQENVAHSPWPHRITVHTDDIQRWAPRQTVRFDLII
HHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECCHHHHCCCCCEEEEEEEE
SNPPYYEPGVECATPQREQARYTATLDHQTLLAIAADCITEDGFFCVVLPEQIGNAFTQQ
CCCCCCCCCCCCCCCCHHHCEEEEECCHHHHHHHHHHHHCCCCEEEEECHHHHCHHHHHH
ALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGSDQHYSESYTALTQA
HHCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
FYLFM
HHHCC
>Mature Secondary Structure 
SQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVADVKRILDIGTGSGLLAL
CCCCCEEECCCCCHHHHHHHHCCEEEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHH
MLAQRTDDNVPIDAVELDAGAAMQAQENVAHSPWPHRITVHTDDIQRWAPRQTVRFDLII
HHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECCHHHHCCCCCEEEEEEEE
SNPPYYEPGVECATPQREQARYTATLDHQTLLAIAADCITEDGFFCVVLPEQIGNAFTQQ
CCCCCCCCCCCCCCCCHHHCEEEEECCHHHHHHHHHHHHCCCCEEEEECHHHHCHHHHHH
ALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGSDQHYSESYTALTQA
HHCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
FYLFM
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA