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The map label for this gene is yfhD [H]

Identifier: 16765887

GI number: 16765887

Start: 2712397

End: 2713941

Strand: Direct

Name: yfhD [H]

Synonym: STM2567

Alternate gene names: 16765887

Gene position: 2712397-2713941 (Clockwise)

Preceding gene: 16765886

Following gene: 16765892

Centisome position: 55.84

GC content: 51.78

Gene sequence:

>1545_bases
TTGAAAAAATTAAAGATTAATTATCTGTTCATCGGCATATTGACGCTGCTGCTGGCAGCAGCCCTTTGGCCCTCAATCCC
CTGGTTCGGTAAAACCGAAAACCATATCGCCGCGATTCAAGCCCGGGGGGTACTGCGCGTCAGTACGATCGACTCGCCAT
TAACCTATTCCGTTATCAACGGTAAAAAATATGGTCTGGACTATGAACTGGCGCAGCAGTTCGCCAACTATCTCGGCGTG
AAGCTGAAAGTGACGGTGCGCCAGAATATCAGCCAGTTGTTTGACGATCTGGATAACGGCAATGCCGACCTGCTCGCGGC
TGGGCTGGTCTACGACAGCGCACGCGTTAAAAACTATCAGCCCGGCCCCATGTATTATTCAGTTTCGCAACAGCTCGTCT
ACCGGGTCGGACAATATCGCCCACGTTCGCTGGCGACCGTTAACGAGAATCAGCTTACCATTGCGCCAGGGCACGTCGTG
GTCAATGATTTACAGCGTTTAAAAGAGACAAAGTTTCCCGACCTGAGCTGGAAAGTGGATGATAAAAAAGGCTCGACGAC
GCTGCTGGAAGAGGTCATCAGCGGCAAACTGGATTACACCATTGCCGATTCAGTGGCGATCAGTCTGTTTCAGCGCGTTC
ATCCCGAGCTGGCCGTGGCGCTGGATGTCACGGATGAACAGCCCGTGACCTGGTTTAGCCGACTGGACGACGATAATACG
CTCTCCGCCGCGCTGCTCGATTTTTTCAATTCGATCAATGAAGACGGTTCTCTGGCGCGGATCGAAGAGAAATATCTGGG
ACATGGCGATGATTTCGACTACGTTGATACCCGCTCTTTCCTGCGAGCGGTAGATAACGTCCTGCCGGAGCTGGAACCGT
TATTTAAAAAATATGCCAAAGAGATAGACTGGCGCCTGCTGGCGGCGATTTCTTATCAGGAATCACACTGGGACCCGCTG
GCGACCTCGCCAACCGGCGTGCGCGGCCTGATGATGCTGACTAAAAATACCGCCCAAAGTCTGGGGCTGACCGACCGTAC
CGATGCGGAGCAAAGCATCAGCGGCGGCGCTCGCTATCTTGAAGATATGATGGCTAAAGTTCCCGAAACCGTTCCGGAAG
ACGAGCGTATCTGGTTTGCTTTAGCCGCCTACAATATGGGTTATGCGCACATGCTCGATGCCAGATCGTTGACGGTAAAA
ACCAAAGGCAATCCGGATAGCTGGACCGATGTGAAGCAGCGTTTGCCTCTGTTAAGCCAAAAACCGTATTACAGTAAGCT
AACCTACGGTTACGCGCGTGGACATGAGGCTTATGCTTATGTGGAAAATATCCGTAAATACCAGATAAGTTTGGTGGGGT
ATTTGCAGGAAAAAGAAAAGCAGGAAGCGGAAGCTATGAAACTGGCGCAGGATTACCCGGCGGTGTCGCCGGAGGAGCTG
AATAAAGCCCCCTTCCCCTTCCTGTCGTTTTTATCGCAGTCATCAGGCTACCTGACGCATTCGCCGTCTTTACTGTTTAC
GCCGCAGAAGAAAGAAGAAAAATAG

Upstream 100 bases:

>100_bases
GGCGCATTGTTACGCAAAATGCCGCTCATTAATGACTTATCTATTGCAGCAAAACATCTTTTTCAGCCCGAGGCAACGCA
CGATCCAGAGAATTAACTAA

Downstream 100 bases:

>100_bases
CGCGATGGTCTTATCGGATGGCGACGCGCAACGTCTTATCCGGCATTGCGCTATACTGCCGGCCCCGCGCCTTCCGCACG
GTCGGCTTTCTTCAGAGCTT

Product: transglycosylase

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGVLRVSTIDSPLTYSVINGKKYGLDYELAQQFANYLGV
KLKVTVRQNISQLFDDLDNGNADLLAAGLVYDSARVKNYQPGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVV
VNDLQRLKETKFPDLSWKVDDKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSRLDDDNT
LSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVDTRSFLRAVDNVLPELEPLFKKYAKEIDWRLLAAISYQESHWDPL
ATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYLEDMMAKVPETVPEDERIWFALAAYNMGYAHMLDARSLTVK
TKGNPDSWTDVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQEAEAMKLAQDYPAVSPEEL
NKAPFPFLSFLSQSSGYLTHSPSLLFTPQKKEEK

Sequences:

>Translated_514_residues
MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGVLRVSTIDSPLTYSVINGKKYGLDYELAQQFANYLGV
KLKVTVRQNISQLFDDLDNGNADLLAAGLVYDSARVKNYQPGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVV
VNDLQRLKETKFPDLSWKVDDKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSRLDDDNT
LSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVDTRSFLRAVDNVLPELEPLFKKYAKEIDWRLLAAISYQESHWDPL
ATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYLEDMMAKVPETVPEDERIWFALAAYNMGYAHMLDARSLTVK
TKGNPDSWTDVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQEAEAMKLAQDYPAVSPEEL
NKAPFPFLSFLSQSSGYLTHSPSLLFTPQKKEEK
>Mature_514_residues
MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGVLRVSTIDSPLTYSVINGKKYGLDYELAQQFANYLGV
KLKVTVRQNISQLFDDLDNGNADLLAAGLVYDSARVKNYQPGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVV
VNDLQRLKETKFPDLSWKVDDKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSRLDDDNT
LSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVDTRSFLRAVDNVLPELEPLFKKYAKEIDWRLLAAISYQESHWDPL
ATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYLEDMMAKVPETVPEDERIWFALAAYNMGYAHMLDARSLTVK
TKGNPDSWTDVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQEAEAMKLAQDYPAVSPEEL
NKAPFPFLSFLSQSSGYLTHSPSLLFTPQKKEEK

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=516, Percent_Identity=84.4961240310078, Blast_Score=881, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 58040; Mature: 58040

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGVLRVSTIDSPLTYSVIN
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCEEEEEECCCCCEEEEEC
GKKYGLDYELAQQFANYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYDSARVKNYQ
CCCCCCCHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHCCCCHHEEEEHHHCCCHHCCCCC
PGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVVVNDLQRLKETKFPDLSWKVD
CCCCEEHHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEC
DKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSRLDDDNT
CCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCCH
LSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVDTRSFLRAVDNVLPELEPLFKKYAK
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIDWRLLAAISYQESHWDPLATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYL
HHCHHEEHEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCHHHHCCHHHHH
EDMMAKVPETVPEDERIWFALAAYNMGYAHMLDARSLTVKTKGNPDSWTDVKQRLPLLSQ
HHHHHHCCCCCCCCCCEEEEEEECCCCHHHEECCCEEEEEECCCCCHHHHHHHHCCCCCC
KPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQEAEAMKLAQDYPAVSPEEL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHC
NKAPFPFLSFLSQSSGYLTHSPSLLFTPQKKEEK
CCCCCHHHHHHHCCCCCEEECCCEEECCCCCCCC
>Mature Secondary Structure
MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGVLRVSTIDSPLTYSVIN
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCEEEEEECCCCCEEEEEC
GKKYGLDYELAQQFANYLGVKLKVTVRQNISQLFDDLDNGNADLLAAGLVYDSARVKNYQ
CCCCCCCHHHHHHHHHHHCEEEEEHHHHHHHHHHHHHCCCCHHEEEEHHHCCCHHCCCCC
PGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVVVNDLQRLKETKFPDLSWKVD
CCCCEEHHHHHHHHHHHCCCCCCEEEECCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEC
DKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSRLDDDNT
CCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHCCCCCH
LSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVDTRSFLRAVDNVLPELEPLFKKYAK
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIDWRLLAAISYQESHWDPLATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYL
HHCHHEEHEEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCCCCCHHHHCCHHHHH
EDMMAKVPETVPEDERIWFALAAYNMGYAHMLDARSLTVKTKGNPDSWTDVKQRLPLLSQ
HHHHHHCCCCCCCCCCEEEEEEECCCCHHHEECCCEEEEEECCCCCHHHHHHHHCCCCCC
KPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQEAEAMKLAQDYPAVSPEEL
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHC
NKAPFPFLSFLSQSSGYLTHSPSLLFTPQKKEEK
CCCCCHHHHHHHCCCCCEEECCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA