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The map label for this gene is narP [H]

Identifier: 16765574

GI number: 16765574

Start: 2346702

End: 2347349

Strand: Direct

Name: narP [H]

Synonym: STM2246

Alternate gene names: 16765574

Gene position: 2346702-2347349 (Clockwise)

Preceding gene: 16765572

Following gene: 16765590

Centisome position: 48.31

GC content: 52.62

Gene sequence:

>648_bases
ATGCCTGAAGTAACACCTTTTCAGGTGCTTATTGTGGACGACCATCCACTTATGCGGCGAGGTATTCGTCAATTACTGGA
ACTGGACCCGGCTTTTCATGTCGTTGCCGAAGCGGGTGACGGGGCGAGTGCGATCGATCTGGCGAATCGCATTGAGCCCG
ATCTGATCCTGCTGGATCTGAATATGAAAGGTCTGAGCGGGTTAGATACCCTGAACGCGCTACGCCGGGATGGTGTGACG
GCGCAAATTATTATTCTTACCGTCTCGGATTCCGCCAGCGACATCTACGCGCTGATCGACGCCGGCGCCGACGGTTATCT
GCTCAAAGATAGCGATCCGGAAGTGCTGCTGGAGGCCATTCGCAAAGGCGCTAACGGCGGTAAAGTCTTTAGCGATCGGG
TCAATGAATATCTGCGTGAGCGCGAACGGTTTGGCGCGCAGGAAGATCCCTTTAGTATCCTGACCGAACGAGAGTTAGAT
GTCTTGCATGAGCTGGCGCAGGGGCTTTCTAACAAACAAATTGCGTCAGTACTGAATATTTCTGAGCAGACGGTTAAGGT
GCACATTCGTAATCTACTTCGCAAGCTAAACGTGCGCTCGCGCGTCGCGGCGACCATTCTATTTTTACAAACACGCGGAA
TGCAGTAA

Upstream 100 bases:

>100_bases
ACTAATTAGGGTAAAATTTACGCGCTTGACAATGTGGCAAATCTGGACGATTTCCGCGCTGAAAACAATAATCATTCTAA
TAAAACTCAGGAGATACAGC

Downstream 100 bases:

>100_bases
CAAGCCAGGCCCGGTGGCGCCGCGCCACCGGGCCGTCAGGGTCTTATTTCTCCTGCGCCAGCCGGATACTGCGCTCTATC
ACCGCCCGCCGGGCGTCACC

Product: transcriptional regulator NarP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPEVTPFQVLIVDDHPLMRRGIRQLLELDPAFHVVAEAGDGASAIDLANRIEPDLILLDLNMKGLSGLDTLNALRRDGVT
AQIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAIRKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELD
VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ

Sequences:

>Translated_215_residues
MPEVTPFQVLIVDDHPLMRRGIRQLLELDPAFHVVAEAGDGASAIDLANRIEPDLILLDLNMKGLSGLDTLNALRRDGVT
AQIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAIRKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELD
VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ
>Mature_214_residues
PEVTPFQVLIVDDHPLMRRGIRQLLELDPAFHVVAEAGDGASAIDLANRIEPDLILLDLNMKGLSGLDTLNALRRDGVTA
QIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAIRKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELDV
LHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=215, Percent_Identity=88.3720930232558, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1787473, Length=209, Percent_Identity=43.5406698564593, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1788222, Length=205, Percent_Identity=32.6829268292683, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790102, Length=194, Percent_Identity=36.0824742268041, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=29.6482412060301, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=27.7486910994764, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788546, Length=200, Percent_Identity=28.5, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=34.1880341880342, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23777; Mature: 23645

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEVTPFQVLIVDDHPLMRRGIRQLLELDPAFHVVAEAGDGASAIDLANRIEPDLILLDL
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHCCCCCEEEEEC
NMKGLSGLDTLNALRRDGVTAQIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAI
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHH
RKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELDVLHELAQGLSNKQIASVLNI
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
SEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PEVTPFQVLIVDDHPLMRRGIRQLLELDPAFHVVAEAGDGASAIDLANRIEPDLILLDL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHCCCCCEEEEEC
NMKGLSGLDTLNALRRDGVTAQIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAI
CCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHHHH
RKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELDVLHELAQGLSNKQIASVLNI
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
SEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501030; 9278503 [H]