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The map label for this gene is pduP [H]

Identifier: 16765381

GI number: 16765381

Start: 2126221

End: 2127615

Strand: Direct

Name: pduP [H]

Synonym: STM2051

Alternate gene names: 16765381

Gene position: 2126221-2127615 (Clockwise)

Preceding gene: 16765380

Following gene: 16765382

Centisome position: 43.77

GC content: 58.64

Gene sequence:

>1395_bases
ATGAATACTTCTGAACTCGAAACCCTGATTCGCACCATTCTTAGCGAGCAATTAACCACGCCGGCGCAAACGCCGGTCCA
GCCTCAGGGCAAAGGGATTTTCCAGTCCGTGAGCGAGGCCATCGACGCCGCGCACCAGGCGTTCTTACGTTATCAGCAGT
GCCCGCTAAAAACCCGCAGCGCCATTATCAGCGCGATGCGTCAGGAGCTGACGCCGCTGCTGGCGCCCCTGGCGGAAGAG
AGCGCCAATGAAACGGGGATGGGCAACAAAGAAGATAAATTTCTCAAAAACAAGGCTGCGCTGGACAACACGCCGGGCGT
AGAAGATCTCACCACCACCGCGCTGACCGGCGACGGCGGCATGGTGCTGTTTGAATACTCACCGTTTGGCGTTATCGGTT
CGGTCGCCCCAAGCACCAACCCGACGGAAACCATCATCAACAACAGTATCAGCATGCTGGCGGCGGGCAACAGTATCTAC
TTTAGCCCGCATCCGGGAGCGAAAAAGGTCTCTCTGAAGCTGATTAGCCTGATTGAAGAGATTGCCTTCCGCTGCTGCGG
CATCCGCAATCTGGTGGTGACCGTGGCGGAACCCACCTTCGAAGCGACCCAGCAGATGATGGCCCACCCGCGAATCGCAG
TACTGGCCATTACCGGCGGCCCGGGCATTGTGGCAATGGGCATGAAGAGCGGTAAGAAGGTGATTGGCGCTGGCGCGGGT
AACCCGCCCTGCATCGTTGATGAAACGGCGGACCTGGTGAAAGCGGCGGAAGATATCATCAACGGCGCGTCATTCGATTA
CAACCTGCCCTGCATTGCCGAGAAGAGCCTGATCGTAGTGGAGAGTGTCGCCGAACGTCTGGTGCAGCAAATGCAAACCT
TCGGCGCGCTGCTGTTAAGCCCTGCCGATACCGACAAACTCCGCGCCGTCTGCCTGCCTGAAGGCCAGGCGAATAAAAAA
CTGGTCGGCAAGAGCCCATCGGCCATGCTGGAAGCCGCCGGGATCGCTGTCCCTGCAAAAGCGCCGCGTCTGCTGATTGC
GCTGGTTAACGCTGACGATCCGTGGGTCACCAGCGAACAGTTGATGCCGATGCTGCCAGTGGTAAAAGTCAGCGATTTCG
ATAGCGCGCTGGCGCTGGCCCTGAAGGTTGAAGAGGGGCTGCATCATACCGCCATTATGCACTCGCAGAACGTGTCACGC
CTGAACCTCGCGGCCCGCACGCTGCAAACCTCGATATTCGTCAAAAACGGCCCCTCTTATGCCGGGATCGGCGTCGGCGG
CGAAGGCTTTACCACCTTCACTATCGCCACACCAACCGGTGAAGGGACCACGTCAGCGCGTACTTTTGCCCGTTCCCGGC
GCTGCGTACTGACCAACGGCTTTTCTATTCGCTAA

Upstream 100 bases:

>100_bases
GCATATTAATTGGGGGTCTTGGCATCAGCGGCGGCAGCGTTGAGCAGGACATGGACATAGCACAGACCGCCATCGCGGCT
ATTAACGTGGGAACTCATCA

Downstream 100 bases:

>100_bases
CTGAGGTCGCGATGAATACCTTCTCACTACAAACGCGGTTGTACAGCGGTCAGGGCAGCCTGGCGGTGCTCAAGCGCTTT
ACCAATAAGCACATCTGGAT

Product: CoA-dependent propionaldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNTSELETLIRTILSEQLTTPAQTPVQPQGKGIFQSVSEAIDAAHQAFLRYQQCPLKTRSAIISAMRQELTPLLAPLAEE
SANETGMGNKEDKFLKNKAALDNTPGVEDLTTTALTGDGGMVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIY
FSPHPGAKKVSLKLISLIEEIAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAITGGPGIVAMGMKSGKKVIGAGAG
NPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKSLIVVESVAERLVQQMQTFGALLLSPADTDKLRAVCLPEGQANKK
LVGKSPSAMLEAAGIAVPAKAPRLLIALVNADDPWVTSEQLMPMLPVVKVSDFDSALALALKVEEGLHHTAIMHSQNVSR
LNLAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFARSRRCVLTNGFSIR

Sequences:

>Translated_464_residues
MNTSELETLIRTILSEQLTTPAQTPVQPQGKGIFQSVSEAIDAAHQAFLRYQQCPLKTRSAIISAMRQELTPLLAPLAEE
SANETGMGNKEDKFLKNKAALDNTPGVEDLTTTALTGDGGMVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIY
FSPHPGAKKVSLKLISLIEEIAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAITGGPGIVAMGMKSGKKVIGAGAG
NPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKSLIVVESVAERLVQQMQTFGALLLSPADTDKLRAVCLPEGQANKK
LVGKSPSAMLEAAGIAVPAKAPRLLIALVNADDPWVTSEQLMPMLPVVKVSDFDSALALALKVEEGLHHTAIMHSQNVSR
LNLAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFARSRRCVLTNGFSIR
>Mature_464_residues
MNTSELETLIRTILSEQLTTPAQTPVQPQGKGIFQSVSEAIDAAHQAFLRYQQCPLKTRSAIISAMRQELTPLLAPLAEE
SANETGMGNKEDKFLKNKAALDNTPGVEDLTTTALTGDGGMVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIY
FSPHPGAKKVSLKLISLIEEIAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAITGGPGIVAMGMKSGKKVIGAGAG
NPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKSLIVVESVAERLVQQMQTFGALLLSPADTDKLRAVCLPEGQANKK
LVGKSPSAMLEAAGIAVPAKAPRLLIALVNADDPWVTSEQLMPMLPVVKVSDFDSALALALKVEEGLHHTAIMHSQNVSR
LNLAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFARSRRCVLTNGFSIR

Specific function: May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI153266822, Length=314, Percent_Identity=24.8407643312102, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788797, Length=471, Percent_Identity=45.4352441613588, Blast_Score=370, Evalue=1e-103,
Organism=Escherichia coli, GI1787493, Length=362, Percent_Identity=32.3204419889503, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787684, Length=425, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI115534176, Length=478, Percent_Identity=22.8033472803347, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=358, Percent_Identity=25.1396648044693, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24666674, Length=404, Percent_Identity=22.029702970297, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012408
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: NA

Molecular weight: Translated: 49046; Mature: 49046

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSELETLIRTILSEQLTTPAQTPVQPQGKGIFQSVSEAIDAAHQAFLRYQQCPLKTRS
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AIISAMRQELTPLLAPLAEESANETGMGNKEDKFLKNKAALDNTPGVEDLTTTALTGDGG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHEEEEEECCCC
MVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIYFSPHPGAKKVSLKLISLIEE
EEEEEECCCCEEECCCCCCCCHHHHHCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHH
IAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAITGGPGIVAMGMKSGKKVIGAGAG
HHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCEEEECCCC
NPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKSLIVVESVAERLVQQMQTFGALLLS
CCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
PADTDKLRAVCLPEGQANKKLVGKSPSAMLEAAGIAVPAKAPRLLIALVNADDPWVTSEQ
CCCCCCEEEEECCCCCCCCEECCCCHHHHHHHCCEECCCCCCEEEEEEECCCCCCCCHHH
LMPMLPVVKVSDFDSALALALKVEEGLHHTAIMHSQNVSRLNLAARTLQTSIFVKNGPSY
HCCCCCEEEECCCCCHHEEEEEHHHCCCHHHHHCCCCCHHHHHHHHHHEEEEEEECCCCE
AGIGVGGEGFTTFTIATPTGEGTTSARTFARSRRCVLTNGFSIR
EEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure
MNTSELETLIRTILSEQLTTPAQTPVQPQGKGIFQSVSEAIDAAHQAFLRYQQCPLKTRS
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
AIISAMRQELTPLLAPLAEESANETGMGNKEDKFLKNKAALDNTPGVEDLTTTALTGDGG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHEEEEEECCCC
MVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIYFSPHPGAKKVSLKLISLIEE
EEEEEECCCCEEECCCCCCCCHHHHHCCCEEEEEECCEEEECCCCCCHHHHHHHHHHHHH
IAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAITGGPGIVAMGMKSGKKVIGAGAG
HHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCEEEECCCC
NPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKSLIVVESVAERLVQQMQTFGALLLS
CCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEC
PADTDKLRAVCLPEGQANKKLVGKSPSAMLEAAGIAVPAKAPRLLIALVNADDPWVTSEQ
CCCCCCEEEEECCCCCCCCEECCCCHHHHHHHCCEECCCCCCEEEEEEECCCCCCCCHHH
LMPMLPVVKVSDFDSALALALKVEEGLHHTAIMHSQNVSRLNLAARTLQTSIFVKNGPSY
HCCCCCEEEECCCCCHHEEEEEHHHCCCHHHHHCCCCCHHHHHHHHHHEEEEEEECCCCE
AGIGVGGEGFTTFTIATPTGEGTTSARTFARSRRCVLTNGFSIR
EEECCCCCCEEEEEEECCCCCCCHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]