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The map label for this gene is steC

Identifier: 16765041

GI number: 16765041

Start: 1790157

End: 1791530

Strand: Reverse

Name: steC

Synonym: STM1698

Alternate gene names: 16765041

Gene position: 1791530-1790157 (Counterclockwise)

Preceding gene: 16765050

Following gene: 16765040

Centisome position: 36.88

GC content: 39.96

Gene sequence:

>1374_bases
ATGCCGTTTACATTTCAGATCGGAAATCATAGTTGCCAGATATCAGAAAGGTATTTAAGAGATATCATCGATAATAAAAG
AGAACATGTTTTTTCAACGTGTGAGAAATTTATAGATTTTTTCAGGAATATATTTACCAGGCGAAGTTTAATTTCTGATT
ATAGAGAAATCTATAATCTACTGTGCCAAAAAAAAGAGCATCCCGATATTAAAGGGCCTTTCTCTCCAGGACCATTTTCG
AAGCGAGATGAAGACTGTACACGATGGCGCCCCCTTCTTGGATATATTAAACTTATTGATGCCTCCAGACCTGAAACAAT
AGATAAATACACTGTAGAGGTATTAGCACATCAAGAAAATATGTTACTACTACAGATGTTTTACGATGGAGTATTAGTGA
CCGAGACGGAGTGTTCTGAACGTTGCGTCGATTTTTTAAAAGAAACGATGTTTAATTATAATAACGGGGAAATTACGCTT
GCCGCTTTGGGTAATGATAATCTACCGCCGAGCGAGGCAGGTAGTAATGGAATCTATGAGGCTTTTGAGCAACGTTTGAT
AGACTTCCTGACCACGCCCGCCACGGCGTCTGGTTATGAGAGCGGCGCTATTGATCAGACGGATGCATCACAACCAGCGG
CAATAGAGGCGTTTATTAACTCGCCGGAGTTTCAGAAAAATATTCGCATGCGTGATATTGAAAAAAATAAAATAGGTAGC
GGAAGTTATGGGACAGTCTATCGGTTACATGATGACTTTGTTGTTAAGATTCCAGTTAATGAGCGGGGAATAAAAGTGGA
TGTTAACTCTCCGGAGCATCGTAATTGTCATCCTGATCGTGTCAGTAAGTATTTGAATATGGCCAATGACGACAAGAATT
TTTCTCGTTCGGCCATCATGAATATTAATGGTAAAGACGTTACGGTTTTAGTTTCAAAATATATTCAAGGTCAGGAGTTC
GATGTTGAAGATGAAGATAACTATCGAATGGCGGAGGCGCTTCTTAAATCCCGGGGGGTTTATATGCATGATATAAATAT
CTTAGGTAATATTCTGGTTAAAGAGGGGGTTCTTTTCTTTGTGGATGGCGATCAAATCGTGTTATCACAAGAATCACGGC
AACAGCGAAGCGTTTCTCTTGCAACAAGGCAACTGGAAGAGCAAATTAAGGCCCATCACATGATAAAATTAAAGCGGGCC
GAGACCGAAGGAAATACTGAAGATGTTGAATATTATAAGTCACTTATTACGGATCTTGATGCGTTAATCGGAGAGGAAGA
ACAGACACCTGCGCCAGGAAGACGTTTTAAACTAGCCGCGCCGGAGGAAGGGACTCTTGTGGCTAAGGTATTAAAGGATG
AATTAAAAAAATAG

Upstream 100 bases:

>100_bases
AATATGAAAAATTTTGGAAATCAGGTGGTTACAGTAGTTACAAATCAGGTTTTTATATGTTTGCATGTGTATTATAATAA
ATTTTCAGAGGATGAGACAT

Downstream 100 bases:

>100_bases
CATTTAGTTCCGTTCTTTTCTGCGAATCGCCGGGGGCACATTCGCTACAGATTTACCGATCAATTATTGAGAGTTGCTAT
TCGCTTAAAGGTCGTTCGGG

Product: inner membrane protein

Products: NA

Alternate protein names: Salmonella translocated effector C

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MPFTFQIGNHSCQISERYLRDIIDNKREHVFSTCEKFIDFFRNIFTRRSLISDYREIYNLLCQKKEHPDIKGPFSPGPFS
KRDEDCTRWRPLLGYIKLIDASRPETIDKYTVEVLAHQENMLLLQMFYDGVLVTETECSERCVDFLKETMFNYNNGEITL
AALGNDNLPPSEAGSNGIYEAFEQRLIDFLTTPATASGYESGAIDQTDASQPAAIEAFINSPEFQKNIRMRDIEKNKIGS
GSYGTVYRLHDDFVVKIPVNERGIKVDVNSPEHRNCHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEF
DVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQESRQQRSVSLATRQLEEQIKAHHMIKLKRA
ETEGNTEDVEYYKSLITDLDALIGEEEQTPAPGRRFKLAAPEEGTLVAKVLKDELKK

Sequences:

>Translated_457_residues
MPFTFQIGNHSCQISERYLRDIIDNKREHVFSTCEKFIDFFRNIFTRRSLISDYREIYNLLCQKKEHPDIKGPFSPGPFS
KRDEDCTRWRPLLGYIKLIDASRPETIDKYTVEVLAHQENMLLLQMFYDGVLVTETECSERCVDFLKETMFNYNNGEITL
AALGNDNLPPSEAGSNGIYEAFEQRLIDFLTTPATASGYESGAIDQTDASQPAAIEAFINSPEFQKNIRMRDIEKNKIGS
GSYGTVYRLHDDFVVKIPVNERGIKVDVNSPEHRNCHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEF
DVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQESRQQRSVSLATRQLEEQIKAHHMIKLKRA
ETEGNTEDVEYYKSLITDLDALIGEEEQTPAPGRRFKLAAPEEGTLVAKVLKDELKK
>Mature_456_residues
PFTFQIGNHSCQISERYLRDIIDNKREHVFSTCEKFIDFFRNIFTRRSLISDYREIYNLLCQKKEHPDIKGPFSPGPFSK
RDEDCTRWRPLLGYIKLIDASRPETIDKYTVEVLAHQENMLLLQMFYDGVLVTETECSERCVDFLKETMFNYNNGEITLA
ALGNDNLPPSEAGSNGIYEAFEQRLIDFLTTPATASGYESGAIDQTDASQPAAIEAFINSPEFQKNIRMRDIEKNKIGSG
SYGTVYRLHDDFVVKIPVNERGIKVDVNSPEHRNCHPDRVSKYLNMANDDKNFSRSAIMNINGKDVTVLVSKYIQGQEFD
VEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFFVDGDQIVLSQESRQQRSVSLATRQLEEQIKAHHMIKLKRAE
TEGNTEDVEYYKSLITDLDALIGEEEQTPAPGRRFKLAAPEEGTLVAKVLKDELKK

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is a kinase, which is required for SPI-2 TTSS-dependent F-actin meshwork formation in infected host cells

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): STEC_SALT1 (D0ZIB5)

Other databases:

- EMBL:   CP001363
- PRIDE:   D0ZIB5
- GenomeReviews:   CP001363_GR
- GO:   GO:0009405

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52303; Mature: 52171

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: BINDING 256-256

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFTFQIGNHSCQISERYLRDIIDNKREHVFSTCEKFIDFFRNIFTRRSLISDYREIYNL
CCEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCQKKEHPDIKGPFSPGPFSKRDEDCTRWRPLLGYIKLIDASRPETIDKYTVEVLAHQEN
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
MLLLQMFYDGVLVTETECSERCVDFLKETMFNYNNGEITLAALGNDNLPPSEAGSNGIYE
EEEEEHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
AFEQRLIDFLTTPATASGYESGAIDQTDASQPAAIEAFINSPEFQKNIRMRDIEKNKIGS
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHCCCCEECCCCCCCC
GSYGTVYRLHDDFVVKIPVNERGIKVDVNSPEHRNCHPDRVSKYLNMANDDKNFSRSAIM
CCCCEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEE
NINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFF
ECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHCCEEEE
VDGDQIVLSQESRQQRSVSLATRQLEEQIKAHHMIKLKRAETEGNTEDVEYYKSLITDLD
ECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHH
ALIGEEEQTPAPGRRFKLAAPEEGTLVAKVLKDELKK
HHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PFTFQIGNHSCQISERYLRDIIDNKREHVFSTCEKFIDFFRNIFTRRSLISDYREIYNL
CEEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCQKKEHPDIKGPFSPGPFSKRDEDCTRWRPLLGYIKLIDASRPETIDKYTVEVLAHQEN
HHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
MLLLQMFYDGVLVTETECSERCVDFLKETMFNYNNGEITLAALGNDNLPPSEAGSNGIYE
EEEEEHHHCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHH
AFEQRLIDFLTTPATASGYESGAIDQTDASQPAAIEAFINSPEFQKNIRMRDIEKNKIGS
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCHHHHCCCCEECCCCCCCC
GSYGTVYRLHDDFVVKIPVNERGIKVDVNSPEHRNCHPDRVSKYLNMANDDKNFSRSAIM
CCCCEEEEECCCEEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEE
NINGKDVTVLVSKYIQGQEFDVEDEDNYRMAEALLKSRGVYMHDINILGNILVKEGVLFF
ECCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHCCEEEE
VDGDQIVLSQESRQQRSVSLATRQLEEQIKAHHMIKLKRAETEGNTEDVEYYKSLITDLD
ECCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHH
ALIGEEEQTPAPGRRFKLAAPEEGTLVAKVLKDELKK
HHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA