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The map label for this gene is ansP [H]

Identifier: 16764928

GI number: 16764928

Start: 1670649

End: 1672142

Strand: Direct

Name: ansP [H]

Synonym: STM1584

Alternate gene names: 16764928

Gene position: 1670649-1672142 (Clockwise)

Preceding gene: 16764925

Following gene: 16764931

Centisome position: 34.39

GC content: 53.48

Gene sequence:

>1494_bases
ATGAAAACACAGACTACGCACGCCGCAGAACAACATGCGGCGAAACGACGCTGGCTGAACGCCCATGAAGAGGGGTATCA
CAAAGCGATGGGGAATCGTCAGGTTCAGATGATTGCTATCGGCGGCGCGATTGGCACCGGTTTATTTTTAGGTGCAGGCG
CCCGATTGCAAATGGCCGGACCGGCACTGGCGCTGGTCTATCTGATATGCGGCATTTTTTCTTTTTTCATTTTACGCGCG
CTGGGCGAACTGGTATTGCATCGCCCTTCCAGCGGGAGCTTCGTCTCCTACGCCCGTGAATTTTTGGGTGAAAAAGCGGC
CTACGTCGCAGGCTGGATGTACTTTATTAACTGGGCGATGACCGGGATCGTCGATATCACCGCAGTGGCGTTATACATGC
ACTACTGGGGCGCATTTGGCGACGTTCCGCAATGGGTGTTCGCGCTCGGCGCGTTAACCATTGTCGGTACCATGAACATG
ATCGGCGTAAAATGGTTTGCCGAAATGGAGTTCTGGTTCGCGCTGATAAAAGTACTCGCCATTGTTATCTTCCTGGTGGT
AGGCACGATTTTTCTCGGTACCGGTCAACCGCTTGAGGGTAATGCCACCGGTTTTCACCTGATTACAGATAATGGCGGCT
TTTTCCCGCACGGCCTGTTGCCCGCGCTGGTACTGATTCAGGGCGTGGTGTTCGCTTTTGCTTCGATTGAACTGGTCGGT
ACCGCCGCTGGGGAGTGCAAAGATCCACAGAAGATGGTGCCAAAAGCCATCAATAGCGTGATCTGGCGTATTGGTCTTTT
CTATGTAGGATCGGTCGTATTGCTGGTTTTGCTGCTGCCGTGGAACGCCTACCAGGCGGGGCAAAGTCCGTTTGTCACCT
TCTTTTCTAAACTTGGCGTGCCTTATATCGGCAGTATTATGAATATCGTGGTGTTAACCGCCGCGCTTTCCAGCCTGAAC
TCCGGGCTTTACTGTACGGGGAGAATTTTACGTTCAATGTCGATGGGGGGTTCCGCGCCGAAATTCATGGCGAAAATGAG
CCGTCAGCATGTGCCCTATGCGGGTATTCTGGCGACTCTGGTGGTTTACGTGGTCGGCGTGTTCCTGAATTACCTGGTCC
CCTCCCGCGTGTTCGAGATCGTTCTTAATTTTGCCTCGCTCGGCATTATCGCGTCGTGGGCGTTTATCATGGTGTGCCAG
ATGCGTTTACGCCAGGCGATAAAAGAAGGCAAAGCCGCAGACGTCAGTTTTAAACTGCCCGGCGCGCCTTTTACCTCCTG
GCTAACACTGCTGTTTTTACTAAGCGTGCTGGTACTCATGGCGTTTGACTACCCGAATGGAACTTATACTATCGCCTCGT
TGCCGCTGATCGCTATTCTGCTGGTCGCCGGCTGGTTTGGCGTGCGACGTCGCGTGGCGGAGATCCATCGCACTGCGCCA
GTGACGGCGGATTCGACAGAGAGTGTCGTATTGAAAGAAGAAGCAGCGACATAA

Upstream 100 bases:

>100_bases
CAGGGAAAAGCGGCATTCGCCATTGCAGGCAATCGATTGGTGAGCGCCCGTCGCGGCATAAGGAATTTTTCTGTCAGGAC
AGGCTATAACAGGTAACGTA

Downstream 100 bases:

>100_bases
CATTCCCCTTCCCCGGCAGCCCCAGGCCTGCCGGGTTTAATGCGCGTTGCCGCCAACACCGCATCGCGCCCAATGCTTAG
TCAGCCTTAATCAACTGCGC

Product: L-asparagine transport protein

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
TAAGECKDPQKMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLN
SGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQ
MRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
VTADSTESVVLKEEAAT

Sequences:

>Translated_497_residues
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
TAAGECKDPQKMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLN
SGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQ
MRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
VTADSTESVVLKEEAAT
>Mature_497_residues
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGIFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
TAAGECKDPQKMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLN
SGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQ
MRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
VTADSTESVVLKEEAAT

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=429, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI258645169, Length=413, Percent_Identity=21.7917675544794, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI110347453, Length=406, Percent_Identity=22.6600985221675, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI258614005, Length=414, Percent_Identity=21.256038647343, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI258614003, Length=414, Percent_Identity=21.256038647343, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081915, Length=499, Percent_Identity=91.3827655310621, Blast_Score=904, Evalue=0.0,
Organism=Escherichia coli, GI1786302, Length=446, Percent_Identity=38.1165919282511, Blast_Score=316, Evalue=3e-87,
Organism=Escherichia coli, GI1786789, Length=461, Percent_Identity=37.527114967462, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1790653, Length=459, Percent_Identity=37.037037037037, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1786602, Length=453, Percent_Identity=37.5275938189845, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI48994972, Length=421, Percent_Identity=38.9548693586698, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI87081708, Length=453, Percent_Identity=33.9955849889625, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789017, Length=440, Percent_Identity=33.1818181818182, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1788480, Length=395, Percent_Identity=34.4303797468354, Blast_Score=234, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17532491, Length=437, Percent_Identity=21.9679633867277, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533459, Length=447, Percent_Identity=23.489932885906, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=455, Percent_Identity=22.4175824175824, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=448, Percent_Identity=30.8035714285714, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320772, Length=438, Percent_Identity=31.0502283105023, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6322892, Length=431, Percent_Identity=33.6426914153132, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324990, Length=498, Percent_Identity=27.5100401606426, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324924, Length=440, Percent_Identity=29.3181818181818, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6324059, Length=466, Percent_Identity=30.0429184549356, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6321629, Length=428, Percent_Identity=28.9719626168224, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321053, Length=427, Percent_Identity=26.9320843091335, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324553, Length=399, Percent_Identity=30.0751879699248, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322967, Length=423, Percent_Identity=28.1323877068558, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319543, Length=426, Percent_Identity=28.4037558685446, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6320717, Length=416, Percent_Identity=28.3653846153846, Blast_Score=146, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6319824, Length=414, Percent_Identity=27.7777777777778, Blast_Score=143, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6324981, Length=423, Percent_Identity=28.3687943262411, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320251, Length=433, Percent_Identity=27.0207852193995, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6319608, Length=449, Percent_Identity=25.8351893095768, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319542, Length=405, Percent_Identity=27.4074074074074, Blast_Score=133, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24666159, Length=437, Percent_Identity=21.7391304347826, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI221512776, Length=437, Percent_Identity=21.7391304347826, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24668806, Length=429, Percent_Identity=23.3100233100233, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356285, Length=429, Percent_Identity=23.3100233100233, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24668802, Length=429, Percent_Identity=23.3100233100233, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54005; Mature: 54005

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAG
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEECC
PALALVYLICGIFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNMIGVKWFAEMEFWFALIKVLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TAAGECKDPQKMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
VVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQMRLRQAIKEGKAADVSFKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTADSTESVVLKEEAAT
CCCCCCCCEEECCCCCC
>Mature Secondary Structure
MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAG
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCEEECC
PALALVYLICGIFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
TGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNMIGVKWFAEMEFWFALIKVLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIELVG
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
TAAGECKDPQKMVPKAINSVIWRIGLFYVGSVVLLVLLLPWNAYQAGQSPFVTFFSKLGV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHCCC
PYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMSMGGSAPKFMAKMSRQHVPYAGILATL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHH
VVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIMVCQMRLRQAIKEGKAADVSFKLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
GAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIASLPLIAILLVAGWFGVRRRVAEIHRTAP
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VTADSTESVVLKEEAAT
CCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]