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The map label for this gene is sseD

Identifier: 16764751

GI number: 16764751

Start: 1486467

End: 1487054

Strand: Direct

Name: sseD

Synonym: STM1401

Alternate gene names: 16764751

Gene position: 1486467-1487054 (Clockwise)

Preceding gene: 16764750

Following gene: 16764752

Centisome position: 30.6

GC content: 49.15

Gene sequence:

>588_bases
ATGGAAGCGAGTAACGTAGCACTGGTATTACCAGCGCCTTCCTTGTTAACACCTTCTTCCACTCCATCTCCCTCCGGGGA
GGGAATGGGTACTGAATCAATGCTTCTGTTATTTGATGATATCTGGATGAAGCTAATGGAGCTTGCCAAAAAGCTGCGCG
ATATCATGCGCAGCTATAACGTAGAAAAACAACGGCTGGCCTGGGAACTGCAAGTCAATGTTTTACAGACGCAAATGAAA
ACAATTGATGAAGCGTTTAGAGCATCAATGATTACTGCGGGTGGCGCAATGTTGTCGGGTGTACTGACGATAGGATTAGG
GGCCGTAGGCGGGGAAACCGGTCTTATAGCGGGTCAAGCCGTAGGCCACACAGCTGGGGGCGTCATGGGCCTGGGGGCTG
GTGTAGCGCAACGTCAAAGTGATCAAGATAAAGCGATTGCCGACCTGCAACAAAATGGGGCCCAATCTTATAATAAATCC
CTGACGGAAATTATGGAGAAAGCAACTGAAATTATGCAGCAAATCATCGGCGTGGGGTCGTCACTGGTCACGGTTCTTGC
TGAAATACTCCGGGCATTAACGAGGTAA

Upstream 100 bases:

>100_bases
GAGCGGTGCCGCGCTTAGAGATGTATTAGATACCATTGATCACTATAGTAGCGTTCAGGCGAGAATAGCTGGCTATCGCG
CTTAATCTGAGGATAAAAAT

Downstream 100 bases:

>100_bases
ACATGGTGCAAGAAATAGAGCAATGGTTACGTCGGCATCAGGTGTTTACTGAGCCTGCATATTTAGGGGAGACCGCCATA
TTACTTGGGCAGCAGTTTAT

Product: translocation machinery component

Products: NA

Alternate protein names: Secretion system effector D

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMKLMELAKKLRDIMRSYNVEKQRLAWELQVNVLQTQMK
TIDEAFRASMITAGGAMLSGVLTIGLGAVGGETGLIAGQAVGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGAQSYNKS
LTEIMEKATEIMQQIIGVGSSLVTVLAEILRALTR

Sequences:

>Translated_195_residues
MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMKLMELAKKLRDIMRSYNVEKQRLAWELQVNVLQTQMK
TIDEAFRASMITAGGAMLSGVLTIGLGAVGGETGLIAGQAVGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGAQSYNKS
LTEIMEKATEIMQQIIGVGSSLVTVLAEILRALTR
>Mature_195_residues
MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMKLMELAKKLRDIMRSYNVEKQRLAWELQVNVLQTQMK
TIDEAFRASMITAGGAMLSGVLTIGLGAVGGETGLIAGQAVGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGAQSYNKS
LTEIMEKATEIMQQIIGVGSSLVTVLAEILRALTR

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 TTSS). After secretion, localizes mainly on the surface of the bacterial cell

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSED_SALTY (Q9R803)

Other databases:

- EMBL:   AJ224892
- EMBL:   AF020808
- EMBL:   AE006468
- RefSeq:   NP_460366.1
- IntAct:   Q9R803
- GeneID:   1252919
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1401
- NMPDR:   fig|99287.1.peg.1357
- HOGENOM:   HBG671310
- OMA:   GWELQVN
- ProtClustDB:   PRK15361
- BioCyc:   STYP99287:STM1401-MONOMER
- GO:   GO:0009405

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20592; Mature: 20592

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMKLMELAKKLRDIMRSYN
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEKQRLAWELQVNVLQTQMKTIDEAFRASMITAGGAMLSGVLTIGLGAVGGETGLIAGQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECHH
VGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGAQSYNKSLTEIMEKATEIMQQIIGVGS
HCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SLVTVLAEILRALTR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMKLMELAKKLRDIMRSYN
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEKQRLAWELQVNVLQTQMKTIDEAFRASMITAGGAMLSGVLTIGLGAVGGETGLIAGQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECHH
VGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGAQSYNKSLTEIMEKATEIMQQIIGVGS
HCCCCCCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SLVTVLAEILRALTR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9786193; 9786194; 11677609