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The map label for this gene is nanM [H]

Identifier: 16764487

GI number: 16764487

Start: 1219460

End: 1220620

Strand: Direct

Name: nanM [H]

Synonym: STM1130

Alternate gene names: 16764487

Gene position: 1219460-1220620 (Clockwise)

Preceding gene: 16764482

Following gene: 16764488

Centisome position: 25.11

GC content: 40.57

Gene sequence:

>1161_bases
ATGGGGATGCAGATGAAAAATTTTAAGAAAATGATGACGCTAATGGCGCTATGTTTCTCAGTTGCTATCACCACATCAGG
ATATGCAACGACGCTTCCTGATATACCAGAACCACTGAAAAATGGTACTGGCGCTATTGATAATAATGGCGTGATTTATG
TCGGCTTAGGTACCGCAGGGACATCCTGGTATAAAATTGATCTTAAAAAGCAACATAAAGACTGGGAGCGTATAAAGTCG
TTTCCTGGTGGAGCTCGTGAGCAATCCGTGTCGGTATTTTTAAATGATGAGCTTTATGTTTTTGGTGGCGTAGGGAAAAA
AAACAGTGAATCACCGTTGCAGGTTTATAGCGATGTGTACAAATACTCACCGGTGAAAAATACATGGCAAAAAGTTGACA
CTATATCTCCAGTTGGATTAACAGGGCATACGGGAGTAAAATTAAATGAAACGATGGTACTTATTACCGGAGGGGTTAAT
GAGCATATCTTTGATAAGTATTTTATTGATATAGCGGCTGCGGCTGCGGATGAAAGTGAAAAAAATAAAGTCATCTATAA
TTATTTTAATAAACCTGCCAAAGATTATTTTTTTAATAAAATCGTATTTATCTACAATGCTAAAGAGAACACATGGAAGA
ATGCCGGTGAGCTGCCAGGCGCGGGGACGGCAGGATCGTCATCGGTAATGGGAAATAATTTCCTGATGCTGATTAATGGT
GAGCTCAAACCGGGTTTACGTACCGATGTGATTTACCGCGCCATGTGGGATAACGATAAGCTAACATGGTTGAAGAACAG
CCAGTTACCGCCATCGCCTGGAGAACAACAGCAGGAAGGGTTGGCCGGAGCATTTTCGGGCTATAGTCACGGTGTCCTGC
TTGTCGGTGGTGGCGCGAATTTTCCGGGAGCAAAACAAAATTATACTAATGGAAAGTTTTATTCCCACGAAGGGATAAAT
AAAAAATGGCGAGATGAAGTCTATGGTTTGATTAATGGTCATTGGCAATATATGGGTAAAATGAAACAACCTCTCGGCTA
TGGTGTATCAGTAAGTTATGGTGATGAAGTTTTCCTTATTGGTGGTGAAAATGCTAAAGGGAAACCTGTTTCGTCTGTAA
CCTCCTTTACCATGCGTGATGGTAATTTATTAATAAAATAA

Upstream 100 bases:

>100_bases
TTATTTTTAGCGCTTGGTCACATTTTGTCATTGTCATTGTTGAAATTGTGCACCATAAGATCACTAATGATGAAGCTTTA
CTCCAATTGTATTTCTTCGC

Downstream 100 bases:

>100_bases
TTTTTTAAATACAAAAATAAAGTTAATTGATGAGCGGAGTATTTTATGAAAATCAACAAATATCTTCTGGGTATGGTTTC
GTTTATAGCATTTTCATCAT

Product: N-acetylneuraminic acid mutarotase

Products: NA

Alternate protein names: N-acetylneuraminate mutarotase; Neu5Ac mutarotase; Sialic acid epimerase [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MGMQMKNFKKMMTLMALCFSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKS
FPGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVN
EHIFDKYFIDIAAAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMGNNFLMLING
ELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGIN
KKWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK

Sequences:

>Translated_386_residues
MGMQMKNFKKMMTLMALCFSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKS
FPGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVN
EHIFDKYFIDIAAAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMGNNFLMLING
ELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGIN
KKWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK
>Mature_385_residues
GMQMKNFKKMMTLMALCFSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKSF
PGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNE
HIFDKYFIDIAAAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMGNNFLMLINGE
LKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINK
KWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK

Specific function: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, whic

COG id: COG3055

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 7 Kelch repeats [H]

Homologues:

Organism=Escherichia coli, GI87082419, Length=374, Percent_Identity=40.9090909090909, Blast_Score=297, Evalue=9e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015915
- InterPro:   IPR006652
- InterPro:   IPR019936 [H]

Pfam domain/function: PF01344 Kelch_1 [H]

EC number: NA

Molecular weight: Translated: 42492; Mature: 42361

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMQMKNFKKMMTLMALCFSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCCCCCCEEEEEECCCC
TSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVY
CEEEEEEEHHHCCHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHH
KYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNEHIFDKYFIDIAAAAADESE
HCCCCHHHHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
KNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMGNNFLMLING
CCCEEEECCCCCHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
ELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGAN
CCCCCCCHHEEEEEEECCCCEEEEECCCCCCCCCCHHHHCCHHHCCCCCCCEEEEECCCC
FPGAKQNYTNGKFYSHEGINKKWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLI
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCEEEEE
GGENAKGKPVSSVTSFTMRDGNLLIK
ECCCCCCCCHHHHEEEEEECCCEEEC
>Mature Secondary Structure 
GMQMKNFKKMMTLMALCFSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAG
CCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCCCCCCEEEEEECCCC
TSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVY
CEEEEEEEHHHCCHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCHHHHHHHHH
KYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNEHIFDKYFIDIAAAAADESE
HCCCCHHHHHHHHCCCCCCCCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
KNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMGNNFLMLING
CCCEEEECCCCCHHHHHCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
ELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGAN
CCCCCCCHHEEEEEEECCCCEEEEECCCCCCCCCCHHHHCCHHHCCCCCCCEEEEECCCC
FPGAKQNYTNGKFYSHEGINKKWRDEVYGLINGHWQYMGKMKQPLGYGVSVSYGDEVFLI
CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEECCCEEEEE
GGENAKGKPVSSVTSFTMRDGNLLIK
ECCCCCCCCHHHHEEEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA