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The map label for this gene is bcfB [H]

Identifier: 16763412

GI number: 16763412

Start: 25112

End: 25798

Strand: Direct

Name: bcfB [H]

Synonym: STM0022

Alternate gene names: 16763412

Gene position: 25112-25798 (Clockwise)

Preceding gene: 16763411

Following gene: 16763413

Centisome position: 0.52

GC content: 50.95

Gene sequence:

>687_bases
ATGAAAAAAAACGTACCGATTTTCCTTCGATTATTGCTACTGCTGTCGGCGGCCGGCCTGTCGTTTGCCGCGCAGGCGGG
AGGCATTGCGCTGGGCGCGACCAGGGTGATTTATCCGCAGGGAAGTAAGCAAACCTCCTTGCCGATTATTAATTCTTCTG
CCAGCAATGTTTTTTTAATTCAGTCATGGGTCGCCAATGCCGATGGTTCACGCTCGACGGATTTTATCATTACGCCGCCT
CTCTTTGTGATCCAGCCTAAAAAAGAAAATATATTACGTATTATGTATGTCGGGCCGTCATTACCGACCGATCGCGAAAG
CGTATTTTATTTAAACAGTAAAGCGATACCCTCTGTCGATAAAAATAAATTGACCGGCAACTCCCTGCAAATTGCGACGC
AAAGCGTGATTAAGCTATTTATCCGCCCGAAAAATCTGGCGGAGGCGCCAGCTCATGCCCCGTCGACGCTTCGCTGCCGT
AACGAGCGCGGCCAGCTAACGATTACTAACCCTTCGCCGTACTACGTTTCGATGGTTGAACTGTATAGCGCGGGGAAAAA
ACTGCCGAATACTATGGTACCGCCGAAAGGCGCGATCACTCTCCCGGCGACGCCCGGCCAGGTATCTTTGCGCACGGTAA
ACGATTTTGGCGCAACGACGCCAGCACGCGTTTGTCCAGCTTCATGA

Upstream 100 bases:

>100_bases
TTCCTTATCGGGATTTTTTTCTCGTCTGTTGGGAGGCGAGAAAGGGGCGTTACGCGCGTCACTGCGCGTAACAAACCGAC
GGCATCAGGATATTACGCAG

Downstream 100 bases:

>100_bases
TGTTATGCGTAATCAGCTTTTCATGACGCGATATTACTCCAGCGTAACTAAACCCGTATTAACCCCGCTGGCGTTGGCTA
TCGCACTGGCGCCTGCGCCG

Product: fimbrial chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKKNVPIFLRLLLLLSAAGLSFAAQAGGIALGATRVIYPQGSKQTSLPIINSSASNVFLIQSWVANADGSRSTDFIITPP
LFVIQPKKENILRIMYVGPSLPTDRESVFYLNSKAIPSVDKNKLTGNSLQIATQSVIKLFIRPKNLAEAPAHAPSTLRCR
NERGQLTITNPSPYYVSMVELYSAGKKLPNTMVPPKGAITLPATPGQVSLRTVNDFGATTPARVCPAS

Sequences:

>Translated_228_residues
MKKNVPIFLRLLLLLSAAGLSFAAQAGGIALGATRVIYPQGSKQTSLPIINSSASNVFLIQSWVANADGSRSTDFIITPP
LFVIQPKKENILRIMYVGPSLPTDRESVFYLNSKAIPSVDKNKLTGNSLQIATQSVIKLFIRPKNLAEAPAHAPSTLRCR
NERGQLTITNPSPYYVSMVELYSAGKKLPNTMVPPKGAITLPATPGQVSLRTVNDFGATTPARVCPAS
>Mature_228_residues
MKKNVPIFLRLLLLLSAAGLSFAAQAGGIALGATRVIYPQGSKQTSLPIINSSASNVFLIQSWVANADGSRSTDFIITPP
LFVIQPKKENILRIMYVGPSLPTDRESVFYLNSKAIPSVDKNKLTGNSLQIATQSVIKLFIRPKNLAEAPAHAPSTLRCR
NERGQLTITNPSPYYVSMVELYSAGKKLPNTMVPPKGAITLPATPGQVSLRTVNDFGATTPARVCPAS

Specific function: Required for the biogenesis of type 1 fimbriae. Binds and interact with fimH [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786743, Length=215, Percent_Identity=50.2325581395349, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1790771, Length=214, Percent_Identity=49.0654205607477, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1787171, Length=217, Percent_Identity=47.926267281106, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1789532, Length=209, Percent_Identity=35.8851674641148, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1786333, Length=213, Percent_Identity=34.2723004694836, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87081806, Length=227, Percent_Identity=31.2775330396476, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87082203, Length=231, Percent_Identity=30.3030303030303, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1786936, Length=219, Percent_Identity=30.5936073059361, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788677, Length=200, Percent_Identity=34, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788428, Length=187, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 24476; Mature: 24476

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNVPIFLRLLLLLSAAGLSFAAQAGGIALGATRVIYPQGSKQTSLPIINSSASNVFLI
CCCCHHHHHHHHHHHHHCCCCEECCCCCEEECCEEEEECCCCCCCCCEEEECCCCCEEEE
QSWVANADGSRSTDFIITPPLFVIQPKKENILRIMYVGPSLPTDRESVFYLNSKAIPSVD
EEECCCCCCCCCCCEEECCCEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCC
KNKLTGNSLQIATQSVIKLFIRPKNLAEAPAHAPSTLRCRNERGQLTITNPSPYYVSMVE
CCCCCCCEEHHHHHHHHHHEECCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCEEHHHH
LYSAGKKLPNTMVPPKGAITLPATPGQVSLRTVNDFGATTPARVCPAS
HHHHHCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKKNVPIFLRLLLLLSAAGLSFAAQAGGIALGATRVIYPQGSKQTSLPIINSSASNVFLI
CCCCHHHHHHHHHHHHHCCCCEECCCCCEEECCEEEEECCCCCCCCCEEEECCCCCEEEE
QSWVANADGSRSTDFIITPPLFVIQPKKENILRIMYVGPSLPTDRESVFYLNSKAIPSVD
EEECCCCCCCCCCCEEECCCEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCC
KNKLTGNSLQIATQSVIKLFIRPKNLAEAPAHAPSTLRCRNERGQLTITNPSPYYVSMVE
CCCCCCCEEHHHHHHHHHHEECCCCCCCCCCCCCCEEEEECCCCCEEEECCCCCEEHHHH
LYSAGKKLPNTMVPPKGAITLPATPGQVSLRTVNDFGATTPARVCPAS
HHHHHCCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]