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The map label for this gene is ttdR [H]

Identifier: 167625800

GI number: 167625800

Start: 4728211

End: 4729125

Strand: Reverse

Name: ttdR [H]

Synonym: Shal_3895

Alternate gene names: 167625800

Gene position: 4729125-4728211 (Counterclockwise)

Preceding gene: 167625801

Following gene: 167625797

Centisome position: 90.48

GC content: 46.34

Gene sequence:

>915_bases
ATGCAACTTAACGATCTCAGACTTTTTGTGCGGGTAGCCGATTGCGGTAGTTTGACTTCGGCAGCTGTTGAGTTAGATAT
TTCCTCTGCGGTAGCGAGTGCAGGACTCAAACGATTAGAGAAGGAGTTAGGCACAACCTTATTTATTCGCAGTACGCGAA
GCTTAAGATTAACCGATGCGGGTGAACGATATCTTATTCATTGTCGTCGTGCTTTATCCGATTTAGAGGTGGGTCAGCGA
GCGATAGAAAGCACTCAGGCGAGTATTTCAGGCTTAGTGAGTCTGTCTGTGCCCTCTGACGTCGGTCGCAATGTCTTGCT
CCCCTGGCTCGATGCGTTTCTACTTGAATACCCTGAGCTAAAGTTGCGTCTACATATAGGCGATAACTTGTCGGATTTTT
ATCGTGACAAGATAGATGTGGCGCTACGCTCAGGCAAACCTAAAGACTCAGCGCTGGTAGCTTTTAAGATCTGTAACTCT
CGTCGTGTACTCTGTGCCTCGCCGGACTACATTAAGCGCTTTGGTGAGGTAAGCTCATTGGAGCAGTTGTCACAGCATAA
TTGTTTGTTTTTTATGCTAGATGAGCGTACCCATGATCAATGGGTTTTCAATAAAAATGGTCAACAGTATAAAGTAAGAG
TGAGTGCTAACCGTACCTGTAATGATGCCGATATAGCGCGGCGTTGGGCGGTTGCAGGCCAGGGGCTGGTATTTAAGTCT
TGGTTAGATCTAACCGATGATATCGAGTCGGGTCGTTTAGTGCCTTTGCTTAATGATTATCAAGGGGAAGAGGCGGATCT
GTACTTAGTTTGTCCGGGCCGGGAGCATGTGACTCCAGTGATCTTGTTGCTTAGAGATATGCTCAGAGAGCGTTGTAAGC
AGCGTTTAAATGGAGTTAAAAGGCTTATGGATTAG

Upstream 100 bases:

>100_bases
AAAGCCTGCTTTCGCAGGCTTTTTTAATGGGTGACGTTTAGCGCAGTATTATCTACAATTTGCTTTAAATTAAAGCTTAT
TTGCAAATGGAATATTGATA

Downstream 100 bases:

>100_bases
TGCCTAACGAATGTTAGCTATAAATAACAGATACAAAAAAACCGCACGAATGCGGTTTTTTTAGTTTATACCAACCTAGG
GTCAGTATAGTAAAAGCTCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MQLNDLRLFVRVADCGSLTSAAVELDISSAVASAGLKRLEKELGTTLFIRSTRSLRLTDAGERYLIHCRRALSDLEVGQR
AIESTQASISGLVSLSVPSDVGRNVLLPWLDAFLLEYPELKLRLHIGDNLSDFYRDKIDVALRSGKPKDSALVAFKICNS
RRVLCASPDYIKRFGEVSSLEQLSQHNCLFFMLDERTHDQWVFNKNGQQYKVRVSANRTCNDADIARRWAVAGQGLVFKS
WLDLTDDIESGRLVPLLNDYQGEEADLYLVCPGREHVTPVILLLRDMLRERCKQRLNGVKRLMD

Sequences:

>Translated_304_residues
MQLNDLRLFVRVADCGSLTSAAVELDISSAVASAGLKRLEKELGTTLFIRSTRSLRLTDAGERYLIHCRRALSDLEVGQR
AIESTQASISGLVSLSVPSDVGRNVLLPWLDAFLLEYPELKLRLHIGDNLSDFYRDKIDVALRSGKPKDSALVAFKICNS
RRVLCASPDYIKRFGEVSSLEQLSQHNCLFFMLDERTHDQWVFNKNGQQYKVRVSANRTCNDADIARRWAVAGQGLVFKS
WLDLTDDIESGRLVPLLNDYQGEEADLYLVCPGREHVTPVILLLRDMLRERCKQRLNGVKRLMD
>Mature_304_residues
MQLNDLRLFVRVADCGSLTSAAVELDISSAVASAGLKRLEKELGTTLFIRSTRSLRLTDAGERYLIHCRRALSDLEVGQR
AIESTQASISGLVSLSVPSDVGRNVLLPWLDAFLLEYPELKLRLHIGDNLSDFYRDKIDVALRSGKPKDSALVAFKICNS
RRVLCASPDYIKRFGEVSSLEQLSQHNCLFFMLDERTHDQWVFNKNGQQYKVRVSANRTCNDADIARRWAVAGQGLVFKS
WLDLTDDIESGRLVPLLNDYQGEEADLYLVCPGREHVTPVILLLRDMLRERCKQRLNGVKRLMD

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=27.2108843537415, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=31.2714776632302, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1786401, Length=256, Percent_Identity=31.25, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=26.7123287671233, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=27.5167785234899, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789639, Length=268, Percent_Identity=28.7313432835821, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787128, Length=279, Percent_Identity=25.089605734767, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1789173, Length=269, Percent_Identity=28.2527881040892, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786448, Length=290, Percent_Identity=28.6206896551724, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI157672245, Length=229, Percent_Identity=27.5109170305677, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=126, Percent_Identity=35.7142857142857, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787601, Length=131, Percent_Identity=28.2442748091603, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788706, Length=300, Percent_Identity=25.6666666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790208, Length=199, Percent_Identity=26.6331658291457, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790011, Length=312, Percent_Identity=26.6025641025641, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34372; Mature: 34372

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNDLRLFVRVADCGSLTSAAVELDISSAVASAGLKRLEKELGTTLFIRSTRSLRLTDA
CCCCCEEEEEEEECCCCCCHHHEEEEHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECC
GERYLIHCRRALSDLEVGQRAIESTQASISGLVSLSVPSDVGRNVLLPWLDAFLLEYPEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCE
KLRLHIGDNLSDFYRDKIDVALRSGKPKDSALVAFKICNSRRVLCASPDYIKRFGEVSSL
EEEEEECCCHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCEEEECCCHHHHHHCCHHHH
EQLSQHNCLFFMLDERTHDQWVFNKNGQQYKVRVSANRTCNDADIARRWAVAGQGLVFKS
HHHHHCCEEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEHH
WLDLTDDIESGRLVPLLNDYQGEEADLYLVCPGREHVTPVILLLRDMLRERCKQRLNGVK
HHCHHCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLMD
HHCC
>Mature Secondary Structure
MQLNDLRLFVRVADCGSLTSAAVELDISSAVASAGLKRLEKELGTTLFIRSTRSLRLTDA
CCCCCEEEEEEEECCCCCCHHHEEEEHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECC
GERYLIHCRRALSDLEVGQRAIESTQASISGLVSLSVPSDVGRNVLLPWLDAFLLEYPEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCCCE
KLRLHIGDNLSDFYRDKIDVALRSGKPKDSALVAFKICNSRRVLCASPDYIKRFGEVSSL
EEEEEECCCHHHHHHHHHHHHEECCCCCCCEEEEEEECCCCEEEECCCHHHHHHCCHHHH
EQLSQHNCLFFMLDERTHDQWVFNKNGQQYKVRVSANRTCNDADIARRWAVAGQGLVFKS
HHHHHCCEEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEHH
WLDLTDDIESGRLVPLLNDYQGEEADLYLVCPGREHVTPVILLLRDMLRERCKQRLNGVK
HHCHHCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RLMD
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]