Click here to switch to the map view.

The map label for this gene is yafV [C]

Identifier: 167625738

GI number: 167625738

Start: 4650059

End: 4650889

Strand: Reverse

Name: yafV [C]

Synonym: Shal_3833

Alternate gene names: 167625738

Gene position: 4650889-4650059 (Counterclockwise)

Preceding gene: 167625739

Following gene: 167625737

Centisome position: 88.98

GC content: 50.66

Gene sequence:

>831_bases
ATGCAAGTCAGCCTACTGCAATGTCAAAGCAGCCGCAGCGTATCGGACAACCTAGCGTTTATCGAATCGCAGCTTAGCCA
GTTACCCCGTAAAGTAGATGAGCCACAGTTGGTGGTGCTGCCGGAGTGTTGCCTGCTCTTTGGTGGTCAGGAAAGCCAGC
AGCTGCAATATGCGGTGGATGCCAAAGATAGCAAACTCAAGCACGATTTAGCTAAGTTAGCGGCGCTATATCGCGTTGTG
ATGGTCGCTGGCAGCATTCCTATTTTGGCCGAGGATGGCCGCGTTTATAATCGCTGTTATGTTTTCGATGCCGATGGCAG
TATCTTAGGTCAATACGATAAATTGCACCTGTTTGATGTTGAGGTGTCTGATGGTACTAAGCAGTATCGGGAAAGCGATG
CGTTTTGCCCCGGTAAGCAGATAGTTGTGGTCGATACCCCTATGGGGAAGTTGGGGCTGGCGATTTGCTACGATATCCGC
TTCCCAGATCTTTTCAGGGCGCTGCGCGAGGCGGGCGCTGAAATGATCGCTGTACCTGCTGCATTTACCAAAGTGACGGG
TGAAGCCCATTGGCAGGTGCTGTTACAGGCTCGCGCTATCGAAACCCAATGTTTTGTCTTAGGGGCTGCACAGTGGGGGC
AACATAATCAAGGTAGCCGAGAGACCTGGGGACAAAGTATGATAGTCGGTCCTTGGGGAAACATTCTTGCCCAAAAAGCG
CAAGGTACGGGTTGGATTCAAGCCGAGATTGAGCTGCAAAGCTTGCAAGAACTTCGCGCTAAAATGCCGGTGATGACTCA
TAATCGATTTGTGTCGCCAAAGCTTAAATAA

Upstream 100 bases:

>100_bases
ACCCTGATAGAGGGCAAGCCGAGTGAGCAAGCGCCTAGTGAGGCCCAAGTTGAGTCATCACCAAAGCCACTGCTAGATGG
GAATAAAGAGGGAGAGTTAG

Downstream 100 bases:

>100_bases
CTCAATAAATTTAGGGGAAGCCGAAACTTGCAGTGAGTGAGACTCGGTTTGCCGAAGTATTTTATCGAATTAATATAAAG
AGAGAAGAGATGTCATTTAT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MQVSLLQCQSSRSVSDNLAFIESQLSQLPRKVDEPQLVVLPECCLLFGGQESQQLQYAVDAKDSKLKHDLAKLAALYRVV
MVAGSIPILAEDGRVYNRCYVFDADGSILGQYDKLHLFDVEVSDGTKQYRESDAFCPGKQIVVVDTPMGKLGLAICYDIR
FPDLFRALREAGAEMIAVPAAFTKVTGEAHWQVLLQARAIETQCFVLGAAQWGQHNQGSRETWGQSMIVGPWGNILAQKA
QGTGWIQAEIELQSLQELRAKMPVMTHNRFVSPKLK

Sequences:

>Translated_276_residues
MQVSLLQCQSSRSVSDNLAFIESQLSQLPRKVDEPQLVVLPECCLLFGGQESQQLQYAVDAKDSKLKHDLAKLAALYRVV
MVAGSIPILAEDGRVYNRCYVFDADGSILGQYDKLHLFDVEVSDGTKQYRESDAFCPGKQIVVVDTPMGKLGLAICYDIR
FPDLFRALREAGAEMIAVPAAFTKVTGEAHWQVLLQARAIETQCFVLGAAQWGQHNQGSRETWGQSMIVGPWGNILAQKA
QGTGWIQAEIELQSLQELRAKMPVMTHNRFVSPKLK
>Mature_276_residues
MQVSLLQCQSSRSVSDNLAFIESQLSQLPRKVDEPQLVVLPECCLLFGGQESQQLQYAVDAKDSKLKHDLAKLAALYRVV
MVAGSIPILAEDGRVYNRCYVFDADGSILGQYDKLHLFDVEVSDGTKQYRESDAFCPGKQIVVVDTPMGKLGLAICYDIR
FPDLFRALREAGAEMIAVPAAFTKVTGEAHWQVLLQARAIETQCFVLGAAQWGQHNQGSRETWGQSMIVGPWGNILAQKA
QGTGWIQAEIELQSLQELRAKMPVMTHNRFVSPKLK

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=177, Percent_Identity=46.3276836158192, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI297632348, Length=177, Percent_Identity=46.3276836158192, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI297632350, Length=177, Percent_Identity=46.3276836158192, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI9910460, Length=275, Percent_Identity=33.0909090909091, Blast_Score=165, Evalue=4e-41,
Organism=Homo sapiens, GI297632346, Length=100, Percent_Identity=44, Blast_Score=95, Evalue=6e-20,
Organism=Escherichia coli, GI1786412, Length=184, Percent_Identity=32.6086956521739, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17556280, Length=237, Percent_Identity=39.2405063291139, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=35.2159468438538, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323383, Length=280, Percent_Identity=31.7857142857143, Blast_Score=162, Evalue=7e-41,
Organism=Drosophila melanogaster, GI17933642, Length=265, Percent_Identity=40, Blast_Score=181, Evalue=6e-46,
Organism=Drosophila melanogaster, GI21355835, Length=272, Percent_Identity=31.6176470588235, Blast_Score=169, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30644; Mature: 30644

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVSLLQCQSSRSVSDNLAFIESQLSQLPRKVDEPQLVVLPECCLLFGGQESQQLQYAVD
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCCCCCCEEEEEEC
AKDSKLKHDLAKLAALYRVVMVAGSIPILAEDGRVYNRCYVFDADGSILGQYDKLHLFDV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEECCCCEEEEEEE
EVSDGTKQYRESDAFCPGKQIVVVDTPMGKLGLAICYDIRFPDLFRALREAGAEMIAVPA
EECCCHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEECH
AFTKVTGEAHWQVLLQARAIETQCFVLGAAQWGQHNQGSRETWGQSMIVGPWGNILAQKA
HHHHCCCCHHHHHHHHHHHHCEEEEEEECHHCCCCCCCCHHHCCCEEEECCCHHHHHHHC
QGTGWIQAEIELQSLQELRAKMPVMTHNRFVSPKLK
CCCEEEEEEEEHHHHHHHHHHCCEEECCCCCCCCCC
>Mature Secondary Structure
MQVSLLQCQSSRSVSDNLAFIESQLSQLPRKVDEPQLVVLPECCLLFGGQESQQLQYAVD
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHCCCCCCCEEEEEEC
AKDSKLKHDLAKLAALYRVVMVAGSIPILAEDGRVYNRCYVFDADGSILGQYDKLHLFDV
CCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCEECCCCEEEEEEE
EVSDGTKQYRESDAFCPGKQIVVVDTPMGKLGLAICYDIRFPDLFRALREAGAEMIAVPA
EECCCHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEECH
AFTKVTGEAHWQVLLQARAIETQCFVLGAAQWGQHNQGSRETWGQSMIVGPWGNILAQKA
HHHHCCCCHHHHHHHHHHHHCEEEEEEECHHCCCCCCCCHHHCCCEEEECCCHHHHHHHC
QGTGWIQAEIELQSLQELRAKMPVMTHNRFVSPKLK
CCCEEEEEEEEHHHHHHHHHHCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]