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The map label for this gene is tldD [H]

Identifier: 167625737

GI number: 167625737

Start: 4648521

End: 4649969

Strand: Reverse

Name: tldD [H]

Synonym: Shal_3832

Alternate gene names: 167625737

Gene position: 4649969-4648521 (Counterclockwise)

Preceding gene: 167625738

Following gene: 167625736

Centisome position: 88.96

GC content: 49.48

Gene sequence:

>1449_bases
ATGTCATTTATAACCCAAGTTGGACAAAGCTTATTACAAGATGGGCTAGCAATCGATGATCTACAAAGCTATTTAAAGCG
TATTCATGAACATCAAATTGATTTCTCAGATCTTTATTTTCAAGGCAGTCGTCACGAATCTTGGGTATTGGAAGATGGCA
TCGTTAAAGATGGTAGCTTTCATATTGAGCGTGGTGTTGGCGTTCGTGCCATTAGTGGCGAGAAAACCGGCTTTGCCTAT
GCCGATGAAATTACACCTGCGGCATTAGAAGCGGCGGCAACCGCTGCTCGTGGTATTGCTACAGCTGGTGGCAATGCGCA
AGTTAATGCTTGGCAGCAACAACAGAGTAAGGCGCTGTATATCAGTTCTGATCCGATTGCTGCAATGGAAGAGGTGAAAA
AGATTGAGCTGCTTAAGCAGGCCGACGTTTATATCCGCAGCTTAGATAGCCGAATTATTCAAGTTGTAGTGAGCTTGTCT
GGTGTTCACGAAGAGATTTTAGTCGCGGCAAGCGATGGCACACTTGCTGCCGATATCCGTCCTTTAGTGCGCTTTAACTG
TAGCGTTATTTTAGAAGAAGACGGTAAGCGCGAGCGCGGCGCCTCTGGCGGCGGCGGGCGTCATGATTACAGCGTGCTAT
TAGAAGATGATAGCGATGGCCTACCTTACTGCTTCGGTTTTGCTCGTGAAGCGGTGCGTCAAGCTCAAGTGAACCTACAC
GCAATTGATGCGCCTGCGGGCGAGATGCCTGTGGTACTCGGTGCTGGCTGGCCGGGCGTGTTACTACACGAAGCCGTGGG
TCATGGCCTTGAAGGTGACTTTAACCGTAAGGGTAGCAGTGCCTTTAGCGGCAAAGTGGGGCAGAAAGTCGCGTCAGAAT
TAGTGACGGTAGTCGATGATGGCACTATGGATAATCGCCGCGGCTCACTGAGTATCGATGACGAAGGTGTACCGACTCAG
AAGACAGTATTGATTGAGAACGGGATCTTAAAAGGCTATATGCAAGATAAGCTCAATGCGCGCCTGATGGGTGAGCAATC
AACGGGTAATGGCCGTCGTGAATCTTATGCACATCTGCCGATGCCACGTATGACAAACACCTATATGGAAGCGGGGGAGT
CAGATCCAGCCGAGATCATCAAGTCGGTTAAGAAGGGTGTCTATGCGCCTAACTTTGGTGGCGGCCAGGTGGATATTACC
TCGGGTAAGTTTGTGTTCTCGGCATCAGAAGCCTATTTGATTGAAAACGGTGAGATCACTCAAGCGATCAAGGGCGCGAC
TCTGATTGGTAATGGTCCTGAATCGATGAGCCAGATCTCTATGGTCGGTAACGATTTAGCGCTGGATAAGGGCGTAGGCG
TCTGCGGTAAAGATGGTCAAAGCGTACCTGTCGGAGTCGGCCAGCCGACATTGAAACTGGATAAGTTGACTGTTGGTGGT
ACAGCGTAA

Upstream 100 bases:

>100_bases
AGCTTAAATAACTCAATAAATTTAGGGGAAGCCGAAACTTGCAGTGAGTGAGACTCGGTTTGCCGAAGTATTTTATCGAA
TTAATATAAAGAGAGAAGAG

Downstream 100 bases:

>100_bases
AGTTAAAACTTTAACCTCCGCTAGGATTTAGTGAGTAAAATATCGACTAAGTCCTAGCGAGTAAGATGTTGCGATGGTAG
TATCTACCGATTAAAAAATA

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSFITQVGQSLLQDGLAIDDLQSYLKRIHEHQIDFSDLYFQGSRHESWVLEDGIVKDGSFHIERGVGVRAISGEKTGFAY
ADEITPAALEAAATAARGIATAGGNAQVNAWQQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLDSRIIQVVVSLS
GVHEEILVAASDGTLAADIRPLVRFNCSVILEEDGKRERGASGGGGRHDYSVLLEDDSDGLPYCFGFAREAVRQAQVNLH
AIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQKVASELVTVVDDGTMDNRRGSLSIDDEGVPTQ
KTVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYAPNFGGGQVDIT
SGKFVFSASEAYLIENGEITQAIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQPTLKLDKLTVGG
TA

Sequences:

>Translated_482_residues
MSFITQVGQSLLQDGLAIDDLQSYLKRIHEHQIDFSDLYFQGSRHESWVLEDGIVKDGSFHIERGVGVRAISGEKTGFAY
ADEITPAALEAAATAARGIATAGGNAQVNAWQQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLDSRIIQVVVSLS
GVHEEILVAASDGTLAADIRPLVRFNCSVILEEDGKRERGASGGGGRHDYSVLLEDDSDGLPYCFGFAREAVRQAQVNLH
AIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQKVASELVTVVDDGTMDNRRGSLSIDDEGVPTQ
KTVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYAPNFGGGQVDIT
SGKFVFSASEAYLIENGEITQAIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQPTLKLDKLTVGG
TA
>Mature_481_residues
SFITQVGQSLLQDGLAIDDLQSYLKRIHEHQIDFSDLYFQGSRHESWVLEDGIVKDGSFHIERGVGVRAISGEKTGFAYA
DEITPAALEAAATAARGIATAGGNAQVNAWQQQQSKALYISSDPIAAMEEVKKIELLKQADVYIRSLDSRIIQVVVSLSG
VHEEILVAASDGTLAADIRPLVRFNCSVILEEDGKRERGASGGGGRHDYSVLLEDDSDGLPYCFGFAREAVRQAQVNLHA
IDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQKVASELVTVVDDGTMDNRRGSLSIDDEGVPTQK
TVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLPMPRMTNTYMEAGESDPAEIIKSVKKGVYAPNFGGGQVDITS
GKFVFSASEAYLIENGEITQAIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQPTLKLDKLTVGGT
A

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=474, Percent_Identity=67.9324894514768, Blast_Score=617, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51225; Mature: 51094

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFITQVGQSLLQDGLAIDDLQSYLKRIHEHQIDFSDLYFQGSRHESWVLEDGIVKDGSF
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHEEECCCCCCEEECCCCCCCCCE
HIERGVGVRAISGEKTGFAYADEITPAALEAAATAARGIATAGGNAQVNAWQQQQSKALY
EEECCCCEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCEECCCCCEEEHHHHCCCCEEE
ISSDPIAAMEEVKKIELLKQADVYIRSLDSRIIQVVVSLSGVHEEILVAASDGTLAADIR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHH
PLVRFNCSVILEEDGKRERGASGGGGRHDYSVLLEDDSDGLPYCFGFAREAVRQAQVNLH
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEE
AIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQKVASELVTVVDD
EEECCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GTMDNRRGSLSIDDEGVPTQKTVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLP
CCCCCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCC
MPRMTNTYMEAGESDPAEIIKSVKKGVYAPNFGGGQVDITSGKFVFSASEAYLIENGEIT
CCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCHH
QAIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQPTLKLDKLTVGG
HHHCCCEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
TA
CC
>Mature Secondary Structure 
SFITQVGQSLLQDGLAIDDLQSYLKRIHEHQIDFSDLYFQGSRHESWVLEDGIVKDGSF
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHEEECCCCCCEEECCCCCCCCCE
HIERGVGVRAISGEKTGFAYADEITPAALEAAATAARGIATAGGNAQVNAWQQQQSKALY
EEECCCCEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCEECCCCCEEEHHHHCCCCEEE
ISSDPIAAMEEVKKIELLKQADVYIRSLDSRIIQVVVSLSGVHEEILVAASDGTLAADIR
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEHHHH
PLVRFNCSVILEEDGKRERGASGGGGRHDYSVLLEDDSDGLPYCFGFAREAVRQAQVNLH
HHHHCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCEEE
AIDAPAGEMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFSGKVGQKVASELVTVVDD
EEECCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GTMDNRRGSLSIDDEGVPTQKTVLIENGILKGYMQDKLNARLMGEQSTGNGRRESYAHLP
CCCCCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCC
MPRMTNTYMEAGESDPAEIIKSVKKGVYAPNFGGGQVDITSGKFVFSASEAYLIENGEIT
CCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCHH
QAIKGATLIGNGPESMSQISMVGNDLALDKGVGVCGKDGQSVPVGVGQPTLKLDKLTVGG
HHHCCCEEECCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCC
TA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]