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The map label for this gene is mlaC [H]

Identifier: 167625600

GI number: 167625600

Start: 4496369

End: 4497040

Strand: Reverse

Name: mlaC [H]

Synonym: Shal_3695

Alternate gene names: 167625600

Gene position: 4497040-4496369 (Counterclockwise)

Preceding gene: 167625601

Following gene: 167625599

Centisome position: 86.04

GC content: 42.41

Gene sequence:

>672_bases
ATGTTTAAAGGTTTTTATCGCAGCGTAATGTTAGCCATGATAGCACTGCTTAGTGTTAATTTGAGTGTTAGTGCTCATGC
AGAGGCAAGTATTGATATCGACCAGAGTAACCCTTTTACTATGGTTGAAGAGGTTGCTAACAAGACCTTTGCCCGCTTTC
ATCAAGATGAGAAGCTGATTGCAACGGATCCTGATCATTTAAAGGTGATCGTGACCGAAGAGTTGATGCCTTATGTTGAT
TATAAGTATGCCTCTTATAAGGTATTAGGTCAGTATCTACGTGATACCACTAAAGACCAGCGCGAGCGCTTTGTTGAAGC
ATTTAAAGGATATCTGATTTCGACTTATGCCCAAGCATTTACTGAGTATACTGACCAAACAGTAGAATATGGCAGAGCCG
AAGACTTTGCCGGTGAGAAGTTTGTCAGCGTCAATATTCAGGTTGTCGAGCAGGGTCGCCCTGCGATTAAGTTACAGTTC
AAGGCGCGTCGCTTAAAAGATGGCACTTGGAAAGCATTTGACTTAATTGCCGAAGGCGTTAGCTTGTTATCATCGAAGCA
ATCGGAGATCACCAACCTTGTGCGTCAGCAAGGGATCGAATCAGTGATTAACTTGCTGAAAGAGAAGACAAATCAGCATA
TTGATTTGGACGCTAACGAGAAAAAAAGCTAG

Upstream 100 bases:

>100_bases
CCCATTCTGCCTTAGTGCTGGAAGAGTTGATTGGCCAGTTCCTTTATAGCATGGGCAAAAAGGATTAGCCTTTTAGAATA
AGTAGTTGGAGTATTTTAAG

Downstream 100 bases:

>100_bases
TGGCCACATTTAAACAGCAAGGGGATAATTGCAGCGTATCGGGTCGTTTAGATCAGGATGCGGTGATCCGGCTGTGGAGT
GGTCGAAGCAATATTTTGGA

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MFKGFYRSVMLAMIALLSVNLSVSAHAEASIDIDQSNPFTMVEEVANKTFARFHQDEKLIATDPDHLKVIVTEELMPYVD
YKYASYKVLGQYLRDTTKDQRERFVEAFKGYLISTYAQAFTEYTDQTVEYGRAEDFAGEKFVSVNIQVVEQGRPAIKLQF
KARRLKDGTWKAFDLIAEGVSLLSSKQSEITNLVRQQGIESVINLLKEKTNQHIDLDANEKKS

Sequences:

>Translated_223_residues
MFKGFYRSVMLAMIALLSVNLSVSAHAEASIDIDQSNPFTMVEEVANKTFARFHQDEKLIATDPDHLKVIVTEELMPYVD
YKYASYKVLGQYLRDTTKDQRERFVEAFKGYLISTYAQAFTEYTDQTVEYGRAEDFAGEKFVSVNIQVVEQGRPAIKLQF
KARRLKDGTWKAFDLIAEGVSLLSSKQSEITNLVRQQGIESVINLLKEKTNQHIDLDANEKKS
>Mature_223_residues
MFKGFYRSVMLAMIALLSVNLSVSAHAEASIDIDQSNPFTMVEEVANKTFARFHQDEKLIATDPDHLKVIVTEELMPYVD
YKYASYKVLGQYLRDTTKDQRERFVEAFKGYLISTYAQAFTEYTDQTVEYGRAEDFAGEKFVSVNIQVVEQGRPAIKLQF
KARRLKDGTWKAFDLIAEGVSLLSSKQSEITNLVRQQGIESVINLLKEKTNQHIDLDANEKKS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=209, Percent_Identity=38.755980861244, Blast_Score=157, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 25468; Mature: 25468

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKGFYRSVMLAMIALLSVNLSVSAHAEASIDIDQSNPFTMVEEVANKTFARFHQDEKLI
CCHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEE
ATDPDHLKVIVTEELMPYVDYKYASYKVLGQYLRDTTKDQRERFVEAFKGYLISTYAQAF
ECCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TEYTDQTVEYGRAEDFAGEKFVSVNIQVVEQGRPAIKLQFKARRLKDGTWKAFDLIAEGV
HHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEHHHCCCCCHHHHHHHHHHH
SLLSSKQSEITNLVRQQGIESVINLLKEKTNQHIDLDANEKKS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MFKGFYRSVMLAMIALLSVNLSVSAHAEASIDIDQSNPFTMVEEVANKTFARFHQDEKLI
CCHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEE
ATDPDHLKVIVTEELMPYVDYKYASYKVLGQYLRDTTKDQRERFVEAFKGYLISTYAQAF
ECCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TEYTDQTVEYGRAEDFAGEKFVSVNIQVVEQGRPAIKLQFKARRLKDGTWKAFDLIAEGV
HHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEEHHHCCCCCHHHHHHHHHHH
SLLSSKQSEITNLVRQQGIESVINLLKEKTNQHIDLDANEKKS
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]