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The map label for this gene is argD [H]

Identifier: 167625516

GI number: 167625516

Start: 4404397

End: 4405614

Strand: Reverse

Name: argD [H]

Synonym: Shal_3610

Alternate gene names: 167625516

Gene position: 4405614-4404397 (Counterclockwise)

Preceding gene: 167625517

Following gene: 167625515

Centisome position: 84.29

GC content: 46.63

Gene sequence:

>1218_bases
ATGAGCGTAAATATGAATCTTACACGTGCCCAATTTGACGAAGTAATGGTGCCTAACTATGCGCCTTCAGCGGTTATTCC
AGTCCGTGGCGAAGGTAGCCGAGTTTGGGATCAAGAAGGTAAAGAGTACATCGACTTTGCTGGTGGTATTGCGGTTAACT
GTTTAGGTCATTGTCATCCTGCTTTGGTTGGCGCGCTAAAGACACAAGGCGAGAAGCTTTGGCATCTTTCTAACGTGATG
ACTAACGAGCCAGCTCTTGAACTTGCGACCAAGCTTGTTGAAGCGACATTTGCCGAACGCGTTTATTTTGCTAACTCAGG
TGCTGAAGCGAATGAAGCAGCGCTTAAGCTAGTACGTCGTTATGCCATGGATAAGTTTGGTGCTGAAAAAGATCAAATTA
TCGCATTCGATAAAGCCTTCCACGGCCGTACTTTCTTCACCGTAAGTGTTGGTGGTCAAGCGGCATACTCAGATGGATTT
GGTCCTAAGCCGCAGAGCATCACACATGTGCCATTTAACGATATTGAAGCATTAGAAGCCGTATTTTCTGATAAGACTTG
TGCGGTAATGATGGAGCCACTGCAAGGTGAAGGTGGCATTATTGATGCGGATCCTGAATTTTTAAAAGCGGTTCGTGCGC
TTTGTGATAAGCATAATGCACTGTTAGTTTTTGATGAAGTTCAAACTGGTGTGGGTCGTCTCGGTGAACTCTATGCGTAT
ATGCGTGGCGATGTCGTTCCTGATGTACTGACAACGGCAAAAGCACTCGGTGGTGGTTTCCCTATTGCTGCGATGCTAAC
GACAAAAGAGATCGCCGCTCACCTTAAGATCGGTACCCATGGTTCTACCTATGGCGGTAACCCGCTAGCTTGTGCTGTGG
GTAATGCGGTAATGGATGTGGTGAATACGCCAGAAGTATTGAACGGCGTTAAGCACCGTGAACAACTGTTTCGCGATGGT
CTAAATAAGATCAACGACAAGTATGATGTATTCTCTGAAATTCGTGGCCAAGGTCTATTGATTGGTGCAGTCGTCAACAG
CAAGTATCAAGGACGCGCAAAAGAGTTCTTGGTTGCAGGCATTAACGAAGGCGTAATGAGCCTTGTTGCTGGTGCAAATG
TTGTTCGCTTTACGCCTTCTCTAGTGATCCCTGAAACCGATATTGCTGAAGGTCTAGCGCGCTTTGAGCGTGCAGTCGCT
AAAGTTGTCGAAGCCTAA

Upstream 100 bases:

>100_bases
CCTAGTTAGACAAACAATCGCCATGTCACCTACAAAAAATAAAGACATTGAGCGGAATACGACCGGCTAAAAGGTCGATA
ATGACAAAGGATGAGAAGGA

Downstream 100 bases:

>100_bases
AAGGCATACGGAGTGTTATCACTGATAGCGCTCCTTTTTTGTCTTTAGGATAACTTGACCGTTTATTGAGCAGTGCTTGT
CATATATTGGTAAGGCTGAC

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSVNMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHPALVGALKTQGEKLWHLSNVM
TNEPALELATKLVEATFAERVYFANSGAEANEAALKLVRRYAMDKFGAEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPQSITHVPFNDIEALEAVFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIAAHLKIGTHGSTYGGNPLACAVGNAVMDVVNTPEVLNGVKHREQLFRDG
LNKINDKYDVFSEIRGQGLLIGAVVNSKYQGRAKEFLVAGINEGVMSLVAGANVVRFTPSLVIPETDIAEGLARFERAVA
KVVEA

Sequences:

>Translated_405_residues
MSVNMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHPALVGALKTQGEKLWHLSNVM
TNEPALELATKLVEATFAERVYFANSGAEANEAALKLVRRYAMDKFGAEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGF
GPKPQSITHVPFNDIEALEAVFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIAAHLKIGTHGSTYGGNPLACAVGNAVMDVVNTPEVLNGVKHREQLFRDG
LNKINDKYDVFSEIRGQGLLIGAVVNSKYQGRAKEFLVAGINEGVMSLVAGANVVRFTPSLVIPETDIAEGLARFERAVA
KVVEA
>Mature_404_residues
SVNMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHPALVGALKTQGEKLWHLSNVMT
NEPALELATKLVEATFAERVYFANSGAEANEAALKLVRRYAMDKFGAEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGFG
PKPQSITHVPFNDIEALEAVFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAYM
RGDVVPDVLTTAKALGGGFPIAAMLTTKEIAAHLKIGTHGSTYGGNPLACAVGNAVMDVVNTPEVLNGVKHREQLFRDGL
NKINDKYDVFSEIRGQGLLIGAVVNSKYQGRAKEFLVAGINEGVMSLVAGANVVRFTPSLVIPETDIAEGLARFERAVAK
VVEA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=34.5454545454545, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI284507298, Length=299, Percent_Identity=34.4481605351171, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI13994255, Length=415, Percent_Identity=30.3614457831325, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=27.7647058823529, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI226442709, Length=390, Percent_Identity=28.2051282051282, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=26.5882352941176, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI24119277, Length=406, Percent_Identity=27.3399014778325, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=23.1884057971014, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=23.1884057971014, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=23.1884057971014, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789759, Length=399, Percent_Identity=65.9147869674186, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI1788044, Length=397, Percent_Identity=59.9496221662469, Blast_Score=506, Evalue=1e-144,
Organism=Escherichia coli, GI1789016, Length=392, Percent_Identity=34.9489795918367, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI145693181, Length=324, Percent_Identity=36.7283950617284, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=32.4937027707809, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786991, Length=410, Percent_Identity=30.2439024390244, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=29.3159609120521, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=377, Percent_Identity=34.7480106100796, Blast_Score=231, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=29.4520547945205, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=269, Percent_Identity=33.8289962825279, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=26.3403263403263, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71981843, Length=160, Percent_Identity=32.5, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=414, Percent_Identity=23.9130434782609, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=36.6161616161616, Blast_Score=264, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.8308457711443, Blast_Score=217, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6324386, Length=359, Percent_Identity=27.8551532033426, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=35.8441558441558, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI161085790, Length=424, Percent_Identity=31.3679245283019, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI28574759, Length=413, Percent_Identity=31.7191283292978, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI21356575, Length=423, Percent_Identity=28.1323877068558, Blast_Score=144, Evalue=9e-35,
Organism=Drosophila melanogaster, GI281366494, Length=428, Percent_Identity=23.1308411214953, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667139, Length=428, Percent_Identity=23.1308411214953, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667143, Length=428, Percent_Identity=23.1308411214953, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43523; Mature: 43392

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHP
CCCCCCCHHHHHHHEECCCCCCCCEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHHHHH
ALVGALKTQGEKLWHLSNVMTNEPALELATKLVEATFAERVYFANSGAEANEAALKLVRR
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
YAMDKFGAEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPQSITHVPFNDIEALEA
HHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCHHHHHHHH
VFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
HHCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIAAHLKIGTHGSTYGGNPLACAVGNAVMDV
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCEEEHHHHHHHHH
VNTPEVLNGVKHREQLFRDGLNKINDKYDVFSEIRGQGLLIGAVVNSKYQGRAKEFLVAG
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHC
INEGVMSLVAGANVVRFTPSLVIPETDIAEGLARFERAVAKVVEA
CCHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVNMNLTRAQFDEVMVPNYAPSAVIPVRGEGSRVWDQEGKEYIDFAGGIAVNCLGHCHP
CCCCCCHHHHHHHEECCCCCCCCEEEECCCCCCCHHHCCCHHHHHCCCHHHHHHHHHHH
ALVGALKTQGEKLWHLSNVMTNEPALELATKLVEATFAERVYFANSGAEANEAALKLVRR
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
YAMDKFGAEKDQIIAFDKAFHGRTFFTVSVGGQAAYSDGFGPKPQSITHVPFNDIEALEA
HHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCEECCCCCCCCCCCEEECCCHHHHHHHH
VFSDKTCAVMMEPLQGEGGIIDADPEFLKAVRALCDKHNALLVFDEVQTGVGRLGELYAY
HHCCCCEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHH
MRGDVVPDVLTTAKALGGGFPIAAMLTTKEIAAHLKIGTHGSTYGGNPLACAVGNAVMDV
HHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCEEEHHHHHHHHH
VNTPEVLNGVKHREQLFRDGLNKINDKYDVFSEIRGQGLLIGAVVNSKYQGRAKEFLVAG
CCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHC
INEGVMSLVAGANVVRFTPSLVIPETDIAEGLARFERAVAKVVEA
CCHHHHHHHHCCCEEEECCCEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]