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The map label for this gene is cysC

Identifier: 167625438

GI number: 167625438

Start: 4305362

End: 4305979

Strand: Reverse

Name: cysC

Synonym: Shal_3530

Alternate gene names: 167625438

Gene position: 4305979-4305362 (Counterclockwise)

Preceding gene: 167625439

Following gene: 167625436

Centisome position: 82.38

GC content: 49.68

Gene sequence:

>618_bases
ATGTCTGATATCGTTTGGCACCAGCATAGTATTGATAAGCAGTCTCGGGCAGATCAGAAAGGACAGAAGCCTATCTTATT
GTGGTTCACCGGCCTGTCAGGTTCTGGTAAATCCACCTTAGCGGGTGCGCTTGAGCGTGCATTATTTGATGCCGGTTTTC
ACACTTACCTGCTTGATGGCGACAATGTGCGCCATGGTCTATGCAAAGATCTCGGCTTTAGCTTGGATGATCGCGATGAG
AATCTTCGCCGCGTCGGCGAGGTTGCCAAACTCATGGTTGATGCAGGTCTTGTGGTGCTGTCGGCCTTTATCTCACCAAC
GCGAGCAGAGCGCGAACGTGTGCGAGCCCTGTTCGATGATGGCCAGTTTATTGAAGTGCATGTATCGACGCCAATAGAGG
TGTGTGAAGCCCGAGATCCTAAAGGCTTGTACAGCAAGGCGCGCGCAGGAGAGATTAAAAACTTTACCGGGATCTCGGCG
TCTTATGAAGTGCCAACTGCTGCCGAGTTAATCATAGATACCAGCAAGGGCGACTTGGCAACGCAAGTGAGTGCACTGCT
AGATTATTTAGCGGCGATTCAAGTTATTGACTCCGAAAAGCTTAAAAAAGCGATTTAA

Upstream 100 bases:

>100_bases
TTGTGCAGTTCTTTTATGTACAGTTCTTTTATTTACAGTTCTTTTATGTGTGCCTCTAAGTTGGCTACGTATTGTATAGA
TTAAGTTTTTTGGAGTTTTT

Downstream 100 bases:

>100_bases
TCAATCTTAAAGTCATGTGAAAACAGGGCTTTCATCGCCTTGATATAGCTTTTGTCGGTATTGAAGTGAATCAACTGTGC
CAACTCATCACCTGTGGGAG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSDIVWHQHSIDKQSRADQKGQKPILLWFTGLSGSGKSTLAGALERALFDAGFHTYLLDGDNVRHGLCKDLGFSLDDRDE
NLRRVGEVAKLMVDAGLVVLSAFISPTRAERERVRALFDDGQFIEVHVSTPIEVCEARDPKGLYSKARAGEIKNFTGISA
SYEVPTAAELIIDTSKGDLATQVSALLDYLAAIQVIDSEKLKKAI

Sequences:

>Translated_205_residues
MSDIVWHQHSIDKQSRADQKGQKPILLWFTGLSGSGKSTLAGALERALFDAGFHTYLLDGDNVRHGLCKDLGFSLDDRDE
NLRRVGEVAKLMVDAGLVVLSAFISPTRAERERVRALFDDGQFIEVHVSTPIEVCEARDPKGLYSKARAGEIKNFTGISA
SYEVPTAAELIIDTSKGDLATQVSALLDYLAAIQVIDSEKLKKAI
>Mature_204_residues
SDIVWHQHSIDKQSRADQKGQKPILLWFTGLSGSGKSTLAGALERALFDAGFHTYLLDGDNVRHGLCKDLGFSLDDRDEN
LRRVGEVAKLMVDAGLVVLSAFISPTRAERERVRALFDDGQFIEVHVSTPIEVCEARDPKGLYSKARAGEIKNFTGISAS
YEVPTAAELIIDTSKGDLATQVSALLDYLAAIQVIDSEKLKKAI

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=201, Percent_Identity=44.2786069651741, Blast_Score=177, Evalue=4e-45,
Organism=Homo sapiens, GI34447231, Length=207, Percent_Identity=41.5458937198068, Blast_Score=174, Evalue=5e-44,
Organism=Homo sapiens, GI62912492, Length=207, Percent_Identity=41.5458937198068, Blast_Score=174, Evalue=6e-44,
Organism=Escherichia coli, GI1789107, Length=197, Percent_Identity=61.4213197969543, Blast_Score=243, Evalue=4e-66,
Organism=Caenorhabditis elegans, GI17542422, Length=197, Percent_Identity=50.761421319797, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6322852, Length=197, Percent_Identity=47.2081218274112, Blast_Score=184, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24667032, Length=179, Percent_Identity=45.8100558659218, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24667028, Length=179, Percent_Identity=45.8100558659218, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24667036, Length=179, Percent_Identity=45.8100558659218, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24667040, Length=179, Percent_Identity=45.8100558659218, Blast_Score=168, Evalue=3e-42,
Organism=Drosophila melanogaster, GI116007838, Length=179, Percent_Identity=45.8100558659218, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24667044, Length=179, Percent_Identity=45.8100558659218, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_SHEHH (B0TTD2)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001675732.1
- ProteinModelPortal:   B0TTD2
- SMR:   B0TTD2
- GeneID:   5905344
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_3530
- HOGENOM:   HBG309946
- OMA:   IVWHQHS
- ProtClustDB:   PRK03846
- BioCyc:   SHAL458817:SHAL_3530-MONOMER
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 22432; Mature: 22301

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: ACT_SITE 105-105

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIVWHQHSIDKQSRADQKGQKPILLWFTGLSGSGKSTLAGALERALFDAGFHTYLLDG
CCCCCCCHHCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECC
DNVRHGLCKDLGFSLDDRDENLRRVGEVAKLMVDAGLVVLSAFISPTRAERERVRALFDD
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GQFIEVHVSTPIEVCEARDPKGLYSKARAGEIKNFTGISASYEVPTAAELIIDTSKGDLA
CCEEEEEECCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHH
TQVSALLDYLAAIQVIDSEKLKKAI
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDIVWHQHSIDKQSRADQKGQKPILLWFTGLSGSGKSTLAGALERALFDAGFHTYLLDG
CCCCCCHHCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECC
DNVRHGLCKDLGFSLDDRDENLRRVGEVAKLMVDAGLVVLSAFISPTRAERERVRALFDD
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
GQFIEVHVSTPIEVCEARDPKGLYSKARAGEIKNFTGISASYEVPTAAELIIDTSKGDLA
CCEEEEEECCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHH
TQVSALLDYLAAIQVIDSEKLKKAI
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA