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The map label for this gene is frr

Identifier: 167624892

GI number: 167624892

Start: 3622813

End: 3623370

Strand: Reverse

Name: frr

Synonym: Shal_2978

Alternate gene names: 167624892

Gene position: 3623370-3622813 (Counterclockwise)

Preceding gene: 167624893

Following gene: 167624891

Centisome position: 69.32

GC content: 45.16

Gene sequence:

>558_bases
GTGATAAACGAAATTAAAAGCGATGCGCAAACTCGCATGGACAAGTGTGTTGAGTCGACAAAAACTCAAATGGCTAAAGT
TCGTACCGGCCGTGCACACCCAAGCTTATTGGATACCATCCAAGTACCTTACTACGGTTCGCTGACTCCACTTAAGCAAG
TTGCAAGTGTATCTATTGGCGATGCGCGCACATTAACGGTATCAGTATTTGACCGTACTATGATTGCAGCTGTTGAAAAG
GCAATCATGAGCTCAGACCTTGGTCTGAACCCAATGTCAGCGGGTGCGACAATTCGCATTCCATTACCTGCATTGACAGA
AGAGCGTCGTAAAGATCTTATCAAGGTTGTTCGTGCTGAAGCCGAGAACGGCCGTATTGCGATTCGTAACGTTCGCCGTG
ATGCTAACTCAAACGTTAAAGAGTTAGAGAAAGAAAAAGAGTGTACGGAAGATGACGTTCGCCGTAGTGAAGATGATGTG
CAGAAGCTAACTGATGCGCACATTAAGCTAGTCGATGACGTTTTAGCTGCAAAAGAAAAGGAACTGATGGAGTTCTAA

Upstream 100 bases:

>100_bases
ATAAACCAGGTGCACTGCGCCGTGTTATCATGGGCGAGCAAGAAGGCACAATGATTAAAGCTGTTTAAGCTATATTTAGT
GACTTAAAAGGACATATAAC

Downstream 100 bases:

>100_bases
ATAGCACTCCTCAGCATAGGGGAGTGTTGACTATTTAGGTTGATTTATAATTAAGCTATATGTGTGTTTCTTGGTTTTTC
GTGAGATATCACGAACTTTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIGDARTLTVSVFDRTMIAAVEK
AIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDV
QKLTDAHIKLVDDVLAAKEKELMEF

Sequences:

>Translated_185_residues
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIGDARTLTVSVFDRTMIAAVEK
AIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDV
QKLTDAHIKLVDDVLAAKEKELMEF
>Mature_185_residues
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIGDARTLTVSVFDRTMIAAVEK
AIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAEAENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDV
QKLTDAHIKLVDDVLAAKEKELMEF

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=29.8850574712644, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=30.6666666666667, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=67.5675675675676, Blast_Score=258, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=32.5714285714286, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_SHEHH (B0TP80)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001675186.1
- ProteinModelPortal:   B0TP80
- SMR:   B0TP80
- GeneID:   5906458
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2978
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   SHAL458817:SHAL_2978-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20626; Mature: 20626

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCC
DARTLTVSVFDRTMIAAVEKAIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAE
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
AENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDVQKLTDAHIKLVDDVLAAKEK
CCCCCEEEHHHHHCCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMEF
HHHCC
>Mature Secondary Structure
MINEIKSDAQTRMDKCVESTKTQMAKVRTGRAHPSLLDTIQVPYYGSLTPLKQVASVSIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCC
DARTLTVSVFDRTMIAAVEKAIMSSDLGLNPMSAGATIRIPLPALTEERRKDLIKVVRAE
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHH
AENGRIAIRNVRRDANSNVKELEKEKECTEDDVRRSEDDVQKLTDAHIKLVDDVLAAKEK
CCCCCEEEHHHHHCCCCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELMEF
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA