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The map label for this gene is yybE [H]

Identifier: 167624867

GI number: 167624867

Start: 3590045

End: 3590884

Strand: Reverse

Name: yybE [H]

Synonym: Shal_2953

Alternate gene names: 167624867

Gene position: 3590884-3590045 (Counterclockwise)

Preceding gene: 167624873

Following gene: 167624859

Centisome position: 68.7

GC content: 50.6

Gene sequence:

>840_bases
ATGAAACTCAGATCACTGAAATATTTTCAATCAGTCTATGAGCTGGGCAGTATCACTGCCGCGGCAAAGGCCTGTTTTGT
GTCTCAGCCCTCTATCACCGCTGCGATTTCACAGCTGGAACAGTTACTTAATATTGAGTTATTTATCCGTCATGCCGGTG
GCGTCAGACCCACCTCAGCCGCCGATAAACTTTATCCCCTAGCGCGTTCTATGAGTGACAATGAGCAGTCGATTTTGCAC
CTGTTTAGCGACGGTCCGGCTCCCATTCCCTTGAAGCTGGGCCTGATGCGCTCCTTAGGCGCCGAGCGCATGAGTTCCTT
GCTTAATGACCTATCGAAACGGATTGATAATCTAGAGCTGACCCTAGTCGATCCCGATGAAGCCTGTGATGCCAGGGTGG
TGCTATCTCAATCGGTTAACAGCGGTGAAGAGTTCTTACCGATCTGGCAAGACAGATACCAACTGGCGATACCAAAGAGT
TGGTCGCTGGCCACCAAACCTGTCATCACGCTTAGCGATCTCGATGGCATCGCGTTTATTAATCGCACCCCCTGTGATGC
GCTGGAGAAGTTAAAGCAGGCGATGGCTGCCAAAGGGGTACAGTTTCAGAATCGAGCCAATATCAGAACTGTCGAATATG
CGTGGCCATTGGTAAACGCCGGAGTGGGTGTAGCACTACTACCTGACTGGGAGGAGATACGCCATAGTGATGGCTTGGTA
TTGAGACCTTTCGAAGGGATAGAGCTGATAAAGAAAATAGGGCTGGCATACACGAGTGGCAGGCAGAGCGAGTCGCTTAT
TACGGCGATTATCTCGGTATGTAAGGCCTGTGCGACTTAG

Upstream 100 bases:

>100_bases
GCTATAGCTGCCAGTTGAGGTCATAGGTAAGTGTGCGTAGACTAGAAAGCAGGCAAAGCGTAAGTCTTTAACACTTAGCT
GCAGCTAAATAGGATGTTTA

Downstream 100 bases:

>100_bases
TGATATGTTTTAATTTTAAAGAAAGCCACTACAAGTTAGTGGCTTTTTAAGATAACGACGGCATTGAGTTCAATAGAGAA
GAGAGAACTCACTTCACTCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKLRSLKYFQSVYELGSITAAAKACFVSQPSITAAISQLEQLLNIELFIRHAGGVRPTSAADKLYPLARSMSDNEQSILH
LFSDGPAPIPLKLGLMRSLGAERMSSLLNDLSKRIDNLELTLVDPDEACDARVVLSQSVNSGEEFLPIWQDRYQLAIPKS
WSLATKPVITLSDLDGIAFINRTPCDALEKLKQAMAAKGVQFQNRANIRTVEYAWPLVNAGVGVALLPDWEEIRHSDGLV
LRPFEGIELIKKIGLAYTSGRQSESLITAIISVCKACAT

Sequences:

>Translated_279_residues
MKLRSLKYFQSVYELGSITAAAKACFVSQPSITAAISQLEQLLNIELFIRHAGGVRPTSAADKLYPLARSMSDNEQSILH
LFSDGPAPIPLKLGLMRSLGAERMSSLLNDLSKRIDNLELTLVDPDEACDARVVLSQSVNSGEEFLPIWQDRYQLAIPKS
WSLATKPVITLSDLDGIAFINRTPCDALEKLKQAMAAKGVQFQNRANIRTVEYAWPLVNAGVGVALLPDWEEIRHSDGLV
LRPFEGIELIKKIGLAYTSGRQSESLITAIISVCKACAT
>Mature_279_residues
MKLRSLKYFQSVYELGSITAAAKACFVSQPSITAAISQLEQLLNIELFIRHAGGVRPTSAADKLYPLARSMSDNEQSILH
LFSDGPAPIPLKLGLMRSLGAERMSSLLNDLSKRIDNLELTLVDPDEACDARVVLSQSVNSGEEFLPIWQDRYQLAIPKS
WSLATKPVITLSDLDGIAFINRTPCDALEKLKQAMAAKGVQFQNRANIRTVEYAWPLVNAGVGVALLPDWEEIRHSDGLV
LRPFEGIELIKKIGLAYTSGRQSESLITAIISVCKACAT

Specific function: Transcriptional Activator For The Hut, Put And Ure Operons And Repressor For The Gdh And Gltb Operons In Response To Nitrogen Limitation. Negative Regulator Of Its Own Expression (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=88, Percent_Identity=38.6363636363636, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI145693105, Length=243, Percent_Identity=25.1028806584362, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30585; Mature: 30585

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRSLKYFQSVYELGSITAAAKACFVSQPSITAAISQLEQLLNIELFIRHAGGVRPTSA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCH
ADKLYPLARSMSDNEQSILHLFSDGPAPIPLKLGLMRSLGAERMSSLLNDLSKRIDNLEL
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
TLVDPDEACDARVVLSQSVNSGEEFLPIWQDRYQLAIPKSWSLATKPVITLSDLDGIAFI
EEECCCCCCCHHHHHHHCCCCCCCCCCCHHCCEEEECCCCCCCCCCCEEEEECCCCEEEE
NRTPCDALEKLKQAMAAKGVQFQNRANIRTVEYAWPLVNAGVGVALLPDWEEIRHSDGLV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCCCCEEECCCHHHHHCCCCEE
LRPFEGIELIKKIGLAYTSGRQSESLITAIISVCKACAT
ECCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKLRSLKYFQSVYELGSITAAAKACFVSQPSITAAISQLEQLLNIELFIRHAGGVRPTSA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCH
ADKLYPLARSMSDNEQSILHLFSDGPAPIPLKLGLMRSLGAERMSSLLNDLSKRIDNLEL
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
TLVDPDEACDARVVLSQSVNSGEEFLPIWQDRYQLAIPKSWSLATKPVITLSDLDGIAFI
EEECCCCCCCHHHHHHHCCCCCCCCCCCHHCCEEEECCCCCCCCCCCEEEEECCCCEEEE
NRTPCDALEKLKQAMAAKGVQFQNRANIRTVEYAWPLVNAGVGVALLPDWEEIRHSDGLV
CCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHCCCCEEECCCHHHHHCCCCEE
LRPFEGIELIKKIGLAYTSGRQSESLITAIISVCKACAT
ECCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]